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TRIM5 restriction of HIV-1 has decreased during evolution leading to humans.
Published 2013“…Original data is found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000301#pbio.1000301-Goldschmidt1" target="_blank">[30]</a> and shows that the antiviral gene TRIM5 restricted HIV-1 better at points in evolution earlier than the chimp–human common ancestor than it does after that. …”
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