Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner by Qian Zhao (217607)

“…The silk ligature was tied around the maxillary second molars for 14 days, during which the CpG+CD40L mixture or PBS was injected into palatal gingiva on days 3, 6, and 9. Results: For both WT and TLR9 KO mice, CpG significantly induced B cell proliferation, increased IL-10 mRNA expression and protein secretion of IL-10 but reduced CD1dhiCD5+ B cells population; local injection of CpG+CD40L mixture significantly decreased alveolar bone loss and the number of TRAP-positive cells adjacent to the alveolar bone surface, and significantly increased the gingival mRNA expression of IL-10 and decreased RANKL and IFN-γ mRNA expression. …”

S C-terminal mutations that decrease ezrin interaction enhance transduction by pseudotyped particles in Vero E6 cells. by Jean Kaoru Millet (117227)

Comparison of WT and mutant SHC014-CoV S ectodomains. by Alexandra L. Tse (20235212)

“…Area under the curve represents protein expression. A835D-containing variants exhibit a large decrease in protein expression relative to the WT and F294L SHC014-CoV spikes. …”

(A) The proportion of fast MyHC myotubes is decreased in Igf-2 deficient mice (maternal disomy Chromosome 7 - MatDi) at E14 by Deborah Merrick (54928)

“…(B) Embryo immunoblotting for Igf-2 demonstrates a stage related increase in Igf-2 protein between E10.5 and E15.5 in WT and absence of Igf-2 in MatDi embryos at E14.5 and E15.5 Tracks 1–4 E10.5, E13.5, E14.5 and E15.5 WT embryos respectively, Track 5 E14.5 MatDi, Track 6 E15.5 MatDi and Track 7 E15.5 WT. …”

Enhanced Nrf2 activity decreases lipid clearance rate and VLDL secretion in Keap1-KD mice. by Jialin Xu (40952)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

HENMT1 loss results in decreased piRNA bulk and the absence of 3’ 2’-O-methylation and stability. by Shu Ly Lim (578590)

Decreased <i>Pax2</i> expression in <i>p53^−/−</i> embryonic kidneys. by Zubaida Saifudeen (135684)

“…<b>B</b>) In situ hybridization. Decreased expression of <i>Pax2</i> mRNA at E12.5. …”

Example of calculating the area under the threshold of the serum albumin curve up to postoperative day 5 (preset threshold = 3.0 g/dL). by Yoonjee Cho (15453454)

The inflammatory process resulting from TIN is decreased in TLR 2, -4, and MyD88 KO mice. by Matheus Correa-Costa (119464)

Microbiocidal activity and limited bacteria-cell contact does not provide for decreased phagocytic clearance of non-swimming bacteria. by Rustin R. Lovewell (205423)

Mutations in the QseE N-terminus impairing interaction with QseG concomitantly decrease QseE activity. by Yvonne Göpel (5549291)

<i>Furin</i> mutant hearts show a decreased in the number of phospo-Smad positive cells at the AV junction. by Laurent Dupays (2940330)

Decreased LysoTracker-positive vacuoles containing <i>S. aureus</i> in <i>PRIP</i>-DKO MEFs. by Kae Harada-Hada (568788)

Neutrophil recruitment into the infected mucosa is decreased in absence of IL-18 but neutrophil depletion does not seem to be a main driver during the initiation of mucosal inflamm... by Anna A. Müller (2853470)

E2-induced PKCδ activation is responsible for the ASL height decrease in CuFi-1 cells. by Vinciane Saint-Criq (479729)

Pdl1 and Orf53 expression in strain W14 increases and decreases Tc toxin release respectively. by Guowei Yang (163967)

Rac1 activity decreases in the presence of DECMA-1 and E-cadherin:Fc in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…Blocking E-cadherin or addition of exogenous E-cadherin:Fc decreased Rac1 activity levels. Fc protein did not affect Rac1 active levels. …”

Elevated cholesterol level in CHO PS1 ΔE9 cells was decreased by the inhibition of cholesterol biosynthesis. by Yoon Young Cho (838272)

Over-expression of ANX RLKs inhibits pollen germination, pollen tube growth, and decreases male transmission efficiency. by Aurélien Boisson-Dernier (490023)