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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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Tribo-Mechanical, Biocompatibility, and Corrosion Properties Investigation of Zirconium and SST 304 by Application of Hydroxyapatite/Reduced Graphene Oxide/Palladium-Platinium Nano...
Published 2020“…In addition, the HA/rGO/Pd-coated SST 304 and the HA/rGO/Pt-coated zirconium substrates were annealed at different temperatures (200, 300, 400, and 600 oC) to investigate their corrosion and wear behaviors. …”
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Thermal and mechanical stability of microwave sintered cold compact bismuth telluride thermoelectric material
Published 2022“…The compacted pellets were sintered in a microwave at 250 °C and 300 °C. Thermogravimetric analysis (TGA), and differential scanning calorimeter (DSC) analysis were performed to study the thermal stability, and nanoindentation, compression test, and microhardness tests were done for mechanical stability. …”
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646
Hydrogen Production via Ethanol Decomposition over Bimetallic Catalyst
Published 2016“…Ethanol decomposition over bimetallic CuCo were conducted using in situ diffuse reflectance infrared fourier transform spectroscopy (DRIFT) study under N2 flow at different temperatures (50, 100, 200, 300, 400°C). Temperature-time profile of CuCo shows an increase in combustion temperature with increase in fuel ratio with maximum temperature at φ = 1 (stoichiometric ratio) and after that it decreases. …”
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Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey
Published 2013“…Univariate sensitivity analysis highlighted that increasing the duration of voriconazole by >1.2 days or decreasing LAmB by >1.0 days changes the result. Monte Carlo Simulation resulted in 69.4% of simulations favouring voriconazole per patient treated.Conclusion: There is a strong likelihood that voriconazole is economically more favourable than LAmB in the empiric treatment of IFI in Turkey.…”
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648
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Investigation of the rheological properties of nanosilica-reinforced polyacrylamide/polyethyleneimine gels for wellbore strengthening at high reservoir temperatures
Published 2019“…Gel strength was observed to increase upon increasing the size of nanosilica initially, and then, it has decreased which gave an optimum nanosilica size of 50 nm. …”
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The association between serum cortisol, thyroid profile, paraoxonase activity, arylesterase activity and anthropometric parameters of undergraduate students under examination stres...
Published 2021“…Fifty-four volunteers were divided into three groups, (n = 18), according to their academic performance, that is, Group A with low CGPA (⩽2.99), Group B with average CGPA (⩾3.00–3.59) and Group C with high CGPA (⩾3.60) and blood samples (3 ml) were taken at three-time intervals, that is, pre-examination, during examination and post examination time interval, at the Department of Physiology, Government College University, Faisalabad. …”
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