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Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…The three compounds could inhibit AR activity up to 90 % at 12.5 μM of phloretin, EGCG and [6]-gingerol with IC50 values of 4.1 μM, 3.7 μM, and 2.4 μM, respectively. The enzyme inhibition kinetics showed non-competitive mode of inhibition for phloretin and EGCG, since it did not alter the Km but the maximum velocity (Vmax) decreased in the presence of the compounds, whereas [6]-gingerol indicated uncompetitive type of inhibition against AR, where it decreased both Km and Vmax upon binding. …”
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Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
Published 2022“…Resilience was assessed using the Connor-Davidson Resilience Scale-10 (CD-RISC-10). Depression, anxiety, and stress were measured by the Depression, Anxiety, and Stress Scale (DASS-21). …”
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Morphology and property changes in PLA/PHBV blends as function of blend composition
Published 2018“…Both the tensile strength and Young?s modulus decreased with increasing PHBV content for the sequence of blends, and both parameters exhibited maximum values for 10?…”
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Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy
Published 2024“…Results: STZ rats exhibited behavioral signs of mechanical and heat hypersensitivity as indicated by significant decreases in the mean paw withdrawal threshold (PWT) and mean paw withdrawal latency (PWL), respectively, at 35 days post-STZ treatment. …”
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Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
Published 2022“…Resilience was assessed using the Connor-Davidson Resilience Scale-10 (CD-RISC-10). Depression, anxiety, and stress were measured by the Depression, Anxiety, and Stress Scale (DASS-21). …”
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