Search alternatives:
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
4 wt » _ wt (Expand Search), i wt (Expand Search), 5 wt (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
4 wt » _ wt (Expand Search), i wt (Expand Search), 5 wt (Expand Search)
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GluN2A(D731N) decreases channel open probability.
Published 2017“…The receptors were activated by EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine at holding potential of -40 mV. The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”
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Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice
Published 2017“…MMP-2 and 9 activity levels in the infarcted myocardium were significantly lower in AIM<sup><b>‒/‒</b></sup> mice than in WT mice.</p><p>Conclusions</p><p>These findings suggest that AIM depletion decreases the levels of M1 macrophages, which are a potent source of MMP-2 and 9, in the infarcted myocardium in the acute phase after MI by promoting macrophage apoptosis, and leads to a decrease in the incidence of cardiac rupture and improvements in survival rates.…”
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CD43<sup>-/-</sup> septic mice exhibit decreased frequencies of apoptotic CD8<sup>+</sup> T<sub>EM</sub> as compared to WT septic mice.
Published 2018“…D) There was a significant decrease in apoptosis of CD44<sup>HI</sup> CD62L<sup>LO</sup> CD8<sup>+</sup> T<sub>EM</sub> in CD43<sup>-/-</sup> septic mice compared to WT septic mice (10.3±1.1 vs 17.9±1.9, p = 0.006). …”
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