Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Here, we synthesized a newseries of <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Here, we synthesized a newseries of <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives. …”

Osy is a half-type ABC transporter. by Yiwen Wang (666361)

Impaired Ubr5 function results in increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

Conditional depletion of RPS0A significantly decreases translation initiation rates. by Tomáš Kouba (153719)

Average velocity per 5% of the distance during normal and 3, 4, and 5 kg assisted 60 m sprints for men and women. by Roland van den Tillaar (6407390)

Higher concentrations of HDACi LBH589 further increase PR and decrease Myc expression in endometrial cancer cells. by Tamar Kavlashvili (849072)

Inhibition of ALK4/5/7 decreases Sertoli cell proliferation in E12.5 fetal testes. by Denise C. Miles (218867)

Administration of APB5, but not APA5, decreases the hyperplasia of alveolar type 2 epithelial cells induced by BLM. by Masami Kishi (6167105)

“…The administration of APB5 markedly decreased the hyperplasia of type 2 epithelial cells induced by BLM. …”

Activation of ERα with estrogen simultaneously increases PR expression and decreases Myc expression in endometrial cancer cells. by Tamar Kavlashvili (849072)

Effects of decreased NSUN2 and METTL1 expression on 5-FU-treatment and heat stress and 5-FU. by Mayumi Okamoto (280005)

Decreased ratio of GSH/GSSG in <i>Slc1a1-</i>HET mice. by Parisa Afshari (4423141)

DOM assembly monitored with temperature and pH reveals that, as either pH decreases or temperature increases, microgel equilibrium size and assembly rates decrease at a non-linear... by Chi-Shuo Chen (234719)

Attenuation of spheroid size decrease or MUC5AC increase by hit compounds. by Pranjali Beri (14945400)

“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”

Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain. by Caio Maximino (100467)

“…<p>(A) Turnover rates, as measured by 5-HIAA:5-HT ratios, normalized to the values of vehicle-treated animals, for the following drugs: fluoxetine (FLX; chronic treatment with 10 mg/kg); chlordiazepoxide (CDZ; 0.02 mg/kg); clonazepam (CLZ; 0.05 mg/kg); diazepam (DZP; 1.25 mg/kg); buspirone (BUS; 50 mg/kg); ethanol (EtOH, 2.5%); dizocilpine (MK; 0.005 mg/kg); verapamil (VER; 5 mg/kg); WAY 100,635 (WAY; 0.03 mg/kg); and SB 224,289 (SB; 2.5 mg/kg). …”

Five compounds significantly decrease MAPK1 phosphorylation in K562 cells. by Pamela Y. Ting (713174)

Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice. by Katherine R. Sadleir (12035242)

“…<p><b>(</b>A and F) Representative immunoblots of hippocampal (A) and cortical (F) lysates of non-transgenic and 5XFAD mice treated with vehicle or nimodipine. …”

Diverse stress conditions trigger a rapid and dramatic decrease in miR-520b-3p and a corresponding increase in ATF5 mRNA over time in HeLa cells. by Kari A. Gaither (9046190)

Thalidomide treatment inhibits growth in RAMEC but not in RAMEC transfected with a dominant negative mutant of CUL5 (^S730ACUL5) cDNA. by Bryan Kunkler (5204327)

Effect of vitamin D derivatives on the proliferation and the differentiation of ATDC5 cells. by Yoshihisa Hirota (616015)