Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…As oncogenic transcriptomic downregulation is often driven by methylation of the promotor region, we explore the demethylation effect of 5-aza-2′-deoxycytidine (decitabine), on the SLFN11 gene. …”

Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism by Tarek Fouda (18472476)

“…</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …”

Wales’ tourists not a burden for local healthcare by Nature Research (16552612)

“…<p>Researchers in southern Wales reviewed nine-years-worth of hospital data and found non-Welsh residents accounted for only 0.5% of unintentional injuries presenting to an emergency department.…”

Low-Dose Eltrombopag in a Patient with Chronic Idiopathic Thrombocytopenic Purpura Post Sleeve Gastrectomy by Mohanad A. Ahmed (14777299)

“…Here we are reporting a 46-year-old female with ITP and sleeve gastrectomy who responded to low-dose eltrombopag 25 mg every other day, which is equivalent to 12.5 mg daily, and maintained adequate platelet counts on this dose.…”

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In addition, treated tumors showed significant dose-dependent decrease in mitotic activity index by 36.5% and 51% in comparison with the control group. …”

Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy by Samson Mathews Samuel (18808246)

“…Assays for cell proliferation, migration and tubulogenesis were also performed. We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …”

Microbiota and sensorial attributes of buffalo meat stored under vacuum packaging: combined impact of marination, citrox and oregano essential oil by Tareq Osaili (11550286)

“…This study aimed to examine the antimicrobial and sensorial effects of natural citrox (0.2% v/w) and oregano essential oil (0.1% v/w) or their combination on marinated buffalo meat stored under vacuum at two storage conditions of 4°C and 12°C. In the control (without marinade), the population of all the spoilage microorganisms increased by 3.8–6.3 and 4.5–6.3 log cfu/g, at 4 and 12°C, respectively, during storage. …”

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Hmwe Hmwe Kyu (8674014)

“…PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. …”

Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…ResultsThe course included 18 participants (10 female, 8 males; average age 40.18 ± 8.46 years) categorized as novice (n = 10, <3 years’ experience), intermediate (n = 5, 3-5 years), and expert (n = 3, >5 years). Video evaluations did not reveal significant differences due to short-term training. …”
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Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India? by Habib Hasan Farooqui (7861166)

“…We conducted interrupted time series analyses by fitting a Poisson regression model. …”

Simultaneous Bilateral Neck of Femur Fracture in a Young Adult with Underlying Metabolic Disturbances by Eslam Alkaramani (14570439)

“…<em>Conclusion</em>. We report this rare case of bilateral neck of femur fracture in a young adult after a generalized seizure attack with underlying metabolic disturbances. …”

Characterizing the dynamics of climate and native desert plants in Qatar by Meshal Abdullah (17746950)

“…By analyzing Landsat satellite images from 1985 to 2022 and their relation to rainfall patterns, we found significant impacts of climatic variables on vegetation coverage, particularly after 1990. …”

BRET-Based Biosensors for Nucleic Acid Detection and Impact of Molecular Crowding Monitoring by Asfia Sultana (19170880)

“…</p><p dir="ltr">We observed the structural fluctuation of flexible linker compared to rigid linker. …”

The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention by Almonzer Al-Qiami (22393303)

“…This leads to a rapid increase in parasympathetic activity, resulting in a decrease in heart rate (HR) and blood pressure, which can potentially lead to bradycardia, and cardiac arrest, with a prevalence of 14.5% during neurointerventional procedures (8). …”

Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 by Sarah Naja (9954737)

“…Furthermore, we conducted a Confirmatory Factor Analysis for the utilized scales.…”

Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows by Tohid, Adibi

“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia by Haitham Elbardisi (14058048)

“…<p dir="ltr">In this study, we investigated the prevalence of sexual dysfunction among males with advanced chronic kidney disease and the effect of treating hyperprolactinemia among these patients. …”

Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters by Lina Majed (7485380)

“…While metabolic, perceptual and spatiotemporal values were sensitive to the smallest change in speed (i.e., 0.5 km·h⁻¹⁾, a significant increase in the rate of carbohydrate oxidation and decrease in % fat oxidation were only observed at speeds above PWS. …”

Dispatchable capacity optimization strategy for battery swapping and charging station aggregators to participate in grid operations by Mingze Zhang (9947863)

“…Also, the aggregator does not worsen the original power load while meeting the EV swapping demand and can decrease the daily load fluctuations by 0.65% and 12.89%, reduce the peak–valley difference by 5.81% and 7.80%, and increase the load rate by 3.67% and 4.08% in working and non-working day situations through providing the dynamic dispatchable capacity for the grid.…”

Dispatchable capacity optimization strategy for battery swapping and charging station aggregators to participate in grid operations by Mingze, Zhang

“…Also, the aggregator does not worsen the original power load while meeting the EV swapping demand and can decrease the daily load fluctuations by 0.65% and 12.89%, reduce the peak–valley difference by 5.81% and 7.80%, and increase the load rate by 3.67% and 4.08% in working and non-working day situations through providing the dynamic dispatchable capacity for the grid.…”
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