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026 decrease » _ decrease (Expand Search)
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ht decrease » _ decrease (Expand Search), we decrease (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
026 decrease » _ decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
ht decrease » _ decrease (Expand Search), we decrease (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
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Respiratory network responses to systemic 5-HT<sub>2A</sub>R and 5-HT<sub>2B</sub>R activation.
Published 2013“…Statistical analysis (paired t-test) is denoted in the panels on the right side. (<b>A</b>–<b>C</b>) Action of 5-HT<sub>2A</sub>R and 5-HT<sub>2B</sub>R ligands in the perfused brainstem preparation. …”
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Effect of 2%, 4%, and 6% HQ cream on hippocampal 5-HT level and 5-HT<sub>1A /1B</sub> receptor expression.
Published 2016“…<p>(A) HQ decreases hippocampus 5-HT level in a dose-dependent manner. …”
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Additional Analysis of visually induced calcium transients in Fig 5.
Published 2020“…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Comparison of the effects of several 5-HT receptor antagonists on the plasma concentrations of metabolites and insulin, following 5-HT injection in sheep and mice.
Published 2014“…</p>b<p>5-HT: serotonin; Me: methysergide; Ke: ketanserin; SB-26: SB-269970; SB-20: SB-204070; Ro: Ro 04-6790; I: increase; D: decrease; N: no change; +: effective in blocking the effect of 5-HT; −: ineffective in blocking the effect of 5-HT.…”
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Schematic representation of possible intracellular 5-HT signaling pathways in chondrocytes.
Published 2017“…Then, the phosphorylated ERK1/2 level is increased through both activation of PKCε and PKCζ; as a result, CCN2 production is decreased. Furthermore, independent of PKC, 5-HT may transmit a certain unknown signal to JNK, which also inhibits the CCN2 production in chondrocytes.…”
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Additional Analysis of visually induced calcium transients in Fig 6.
Published 2020“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”
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Serotonin modulates L2 neuron visually induced calcium transient kinetics.
Published 2020“…Light or dark stimuli (A, middle panel, white and black vertical bars respectively) were flashed at random every 5 s for 6 min. …”
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RhoA gene expression and activity are impacted with increased intracellular 5HT.
Published 2020“…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …”
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Respiratory network responses to systemic 5-HT<sub>2A</sub>R and 5-HT<sub>2B</sub>R antagonist applications of in situ rats.
Published 2013“…(<b>A</b>) Application of the specific 5-HT<sub>2A</sub>R antagonist Altanserin (blue trace) significantly decreased phrenic nerve activity (PNA) by decreasing the amplitude. …”
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Effect of 2% HQ, 0.05% INN and 0.1% TAC on hippocampal 5-HT level and 5-HT<sub>1A /1B</sub> receptor expression.
Published 2016“…Scale bar = 100μm. (E) The expression of 5-HT<sub>1A</sub> and 5-HT<sub>1B</sub> receptors was decreased in INN and TAC-treated mice. …”