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026 decrease » _ decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
ht decrease » _ decrease (Expand Search), we decrease (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
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Genetic deletion of P2rx7 leads to the alteration of NA and 5-HT levels (A, B), elevation of<sup>3</sup>H-Citalopram binding sites and 5-HT uptake (C) in the mouse hippocampus.
Published 2013“…<p>A, B/NA and 5-HT levels were analyzed using HPLC in the hippocampus of naive and LPS (1 mg/kg)-treated P2rx7+/+ and P2rx7−/− mice. …”
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5-HT treatment modulates TGFβ3 mediated gene expression.
Published 2012“…<p><b>A</b>) TGFβ3 mRNA transcripts increase with physiological 5-HT (470 nM, <i>5-HT</i>), but decrease at high dose (47 µM, <i>5-HT+</i>). αSMA, RhoA, and col1α2, were not affected by physiological 5-HT dose, but were significantly downregulated with high 5-HT treatment. …”
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Downstream molecular effects of knockdown of the expression of 5-HT<sub>1B</sub> and 5-HT<sub>1D</sub> receptors, on invasion and proliferation biomarkers in PaCa cells.
Published 2014“…<p>(<b>A–B</b>) The effect of siRNAs-mediated 5-HT<sub>1B</sub> and 5-HT<sub>1D</sub> receptors down-regulation on β1 integrin/ECM-mediated downstream signaling in PANC-1 (A) and MIAPaCa-2 cells (B). …”
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Myoendothelial and/or endothelial gap junctions participate to the calcium and contractile responses to 5-HT.
Published 2009“…<p>Typical traces of simultaneous recordings of intracellular calcium (top panel) and contraction (bottom panel) induced by 5HT 10 µM are shown in A. 300 µM <sup>37-43</sup>Gap 27 was introduced into the bath where indicated. …”
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(A) Activation maps contrasting the control group with the 5-HT- group showing a significant effect for aversive prediction error signals (PE) in the orbitofrontal cortex (left) an...
Published 2013“…(B) Peak voxel parameter estimates show decreased aversive PE signals for the 5-HT depleted group (TRP-) compared to the control group (TRP+). …”
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DataSheet_1_PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization.pdf
Published 2021“…In addition, the levels of endogenous 5-HT<sub>2A</sub> were decreased on the cell surface of primary cultured cortical neurons after PACAP stimulation and were increased in frontal cortex cell membranes of Pacap<sup>−/−</sup> mice. …”
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Table_1_Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT2A receptors in the ventral hippocampus.DOCX
Published 2023“…The results demonstrated that trait sensitivity to negative feedback is associated with increased mRNA expression of the 5-HT2A receptors in the rat ventral hippocampus (vHipp). …”
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Presentation_1_Constitutive Serotonin Tone Modulates Molecular and Behavioral Response to Chronic Fluoxetine Treatment: A Study on Genetic Rat Model.pdf
Published 2021“…Platelet 5HT levels, a recognized indicator of SSRI efficacy, were decreased by fluoxetine treatment in both 5HT-sublines. …”
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Rapid degeneration of 5-HT neurons in SERT-Cre<sup>cre/wt</sup> Munc18-1<sup>lox/lox</sup> mice.
Published 2013“…(O) Analysis of the number of 5-HT cell bodies in the sections showed that there is no difference at E16, but at E18 and P2 there is a decrease of 80% to 90% in the number of 5-HT cell bodies in SERT-Cre<sup>cre/wt</sup> Munc18-1<sup>lox/lox</sup> sections. …”
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In vivo assessment of 5-HT<sub>1A</sub> and 5-HT<sub>2</sub> post-synaptic receptor function using 8-OH-DPAT-induced change of corticosterone levels and DOI-induced head-twitches.
Published 2013“…<p>Compared to paired-saline injected animals, administration of the 5-HT<sub>1A</sub> agonist 8-OH-DPAT (0.3 mg/kg, s.c.) significantly increased corticosterone levels in both (A) male and (B) female mice, regardless of the genotype. …”
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SMNΔ7 NMJs display a decrease in synaptic efficacy.
Published 2010“…SMNΔ7 3.16±0.26 min<sup>−1</sup>, <i>p</i><0.0001;), EPP amplitude (control 7.27±0.34 mV vs. …”
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Change in levels of 5HT and its related substances in the brain of queen associated with early colony establishment.
Published 2013“…B: Change in level of 5HT in the brain of queen associated with early colony establishment. 5HT significantly decreased after queen started establishing a colony. …”
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Summary of the effect of maternal immune activation on serotonin and dopamine.
Published 2017“…The cerebral 5-HT levels were significantly decreased at 5 and 8 weeks old (solid arrow), whereas the DA levels exhibited a trend towards a decrease (dotted arrow). …”