Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity by Kaytee L. Pokrzywinski (3605435)

“…Mitochondrial status was evaluated by measuring superoxide production, mitochondrial membrane depolarization, oxygen consumption, extracellular acidification and mRNA or protein levels of the RC complexes along with TCA cycle activity. In this study, we demonstrated that all investigated MTAs impair mitochondrial health and decrease mtDNA integrity in MDA-MB-231 and H23 cells. …”

DataSheet_1_PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization.pdf by Atsuko Hayata-Takano (525514)

“…Here, we examined whether PACAP modulates 5-HT_2A signaling by addressing cellular protein localization. …”

Image_5.TIF by Lorena Pizarro (396472)

“…Overexpression of SlPRA1A strongly decreases LeEIX2 endosomal localization, as well as LeEIX2 protein levels. …”

Gibberellic acid in <i>Citrus</i> spp. flowering and fruiting: A systematic review by Alfonso Garmendia (814091)

“…The results on yield were highly erratic as we found increases, decreases, no effects or variable effects.…”

Phlorizin decreased renal GTTR uptake, and increased serum drug levels <i>in vivo</i>. by Meiyan Jiang (438439)

Klf5 activates the transcription of the eIF5a gene through direct binding to its promoter. by Dong Ma (584680)

Subjects:

Klf5 and eIF5a suppress Ang II–induced expression of NOX1 in VSMCs. by Dong Ma (584680)

Subjects:

Image 5_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif by Chen Wang (88408)

“…</p>Methods<p>To identify potential regulators of immunotherapy response, we conducted a comprehensive analysis of colorectal cancer datasets from The Cancer Genome Atlas (TCGA). …”

<i>prx-5/6</i> mutations likely cause a decrease in mmBCFA degradation. by Rencheng Wang (463927)

“…<i>elo-5</i>(<i>lf</i>)<i>; Ex</i>[<i>elo-6</i>] is a transgenic strain that significantly overexpressed the <i>elo-6</i> gene and was not sufficient to suppress the L1 arrest phenotype of <i>elo-5</i>(<i>lf</i>). …”

HAstV-1 infection leads to a decrease in epithelial markers while increasing mesenchymal markers. by Virginia Hargest (12447014)

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…Treatment of 4,4-difluoro-8-(2,5-dibromo-3-thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene with Br₂ gave red-shifted UV−vis absorption band features that grow with increasing dipyrrin bromination. …”

The effect of STOX1A on cell proliferation in the neuroblastoma cell-line SH-SY5Y. by Daan van Abel (214754)

“…<p>(A) The proliferation curve shows significantly decreased cell proliferation for STOX1A siRNA transfected SH-SY5Y cells compared to scrambled controls after 1, 2, and 3 days in culture. …”

CYP3A94 activity is significantly increased in V79-CYP3A94/DD-POR cells, but decreases after incubation with Shield-1. by Ramona Dettwiler (664360)