Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

Subjects:

LOH unlinks 189R/R from a stop codon with masking effects on phenotype. by Pétra Vande Zande (17628246)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

VPA decreases cell proliferation. by Muriel Rhinn (406515)

TUDCA decreases ER stress in HOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”

FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma. by Laura L. Stafman (6577184)

“…<p>(A) HuH6 cells (2.5 x 10⁶ cells in 25% Matrigel) were injected subcutaneously into the right flank of 6-week-old female athymic nude mice. …”

Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

Subjects:

Ce6 decreases the amount of TMV PQS5 upon photo-irradiation. by Congbao Xie (17599247)

A nonsense mutation in <i>anmK</i> contributes to decreased growth of AC811 in Arabidopsis leaves. by Megan R. O’Malley (7485323)

Expression of <i>uvrC</i> is decreased in AC811 but not in Δ<i>gacA</i>-1. by Megan R. O’Malley (7485323)

Fold change with steady state myocardial mRNA levels for components of the inflammasome. by Stephanie L. Samani (17896610)

5-fluorouracil decreases rates of persistent and reappearing actinic keratoses: The VAKCC Trial by Moniyka Sachar (9399032)

Viral loads of CrPV and DCV across host species during single and coinfection. by Ryan M. Imrie (15810854)

L1 animals lacking <i>adr-2</i> have decreased expression of genes regulated by insulin signaling. by Ananya Mahapatra (17041557)

Viral loads of CrPV and DCV across DGRP lines during single and coinfection. by Ryan M. Imrie (15810854)

Genetic correlations in viral load between single and coinfections of CrPV and DCV. by Ryan M. Imrie (15810854)

Interspecific correlations in viral load between single and coinfections of CrPV and DCV. by Ryan M. Imrie (15810854)

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Inhibition of autophagic flux increases EtOH-induced oxidative stress, induces mitochondrial depolarization, and decreases cell viability. by Prasanna M. Chandramouleeswaran (3176268)