Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Inhibition of G9a decreases the tumorigenicity of neuroblastoma cells. by Xiao-Xue Ke (626989)

Gene deletion on chromosome 10. by Sophia Bigot (16469992)

Subjects:

Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe‑dPro] Decreases M... by Zoe M. Koerperich (8231850)

Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe‑dPro] Decreases M... by Zoe M. Koerperich (8231850)

Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe‑dPro] Decreases M... by Zoe M. Koerperich (8231850)

Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe‑dPro] Decreases M... by Zoe M. Koerperich (8231850)

Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe‑dPro] Decreases M... by Zoe M. Koerperich (8231850)

Proteome analysis of plasma from ATTR individuals. by Gonçalo da Costa (198731)

Selection of the 25 candidate unigenes most up-regulated and the 25 candidate unigenes most down-regulated of IAC Imperador (decreasing order of log2FoldChange). by Daiana Alves da Silva (5529677)

Infection decreases short chain phospholipids in the intestines of <i>V</i>. <i>cholerae</i>-infected flies. by Audrey S. Vanhove (4090594)

Image_2_ACEI/ARB Medication During ICU Stay Decrease All-Cause In-hospital Mortality in Critically Ill Patients With Hypertension: A Retrospective Cohort Study Based on Machine Lea... by Boshen Yang (11935403)

Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Homozygous deletion of <i>ERG251</i> leads to increased sensitivity to cell membrane and osmotic stress but decreased sensitivity to oxidative stress. by Xin Zhou (54275)

“…Volcano plot for differentially expressed genes (log₂ fold change ≥ 1 or ≤-1 and adjusted <i>p</i>-value < 0.05) in the <i>erg251Δ/Δ</i> mutant compared to <i>ERG251/ERG251</i> in YPAD. …”

Complete data. by Jan Víteček (11434774)

“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”

Fig 4 - by Jan Víteček (11434774)

“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”

AgLDL induce the decrease of ΔΨm and ATP in THP-1 macrophages, without mtROS or apoptosis. by Gabriela M. Sanda (10031559)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

Image_2_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri... by Shirin Hasan (7894118)

“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”

<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron. by Diane E. Brown (160264)

“…The infected mouse had 11.5-fold more TER119^med pro-erythroblasts and 5.5-fold more TER119^high erythroblasts than the mock-infected mouse. …”