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sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
026 decrease » _ decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a sizes » _ sizes (Expand Search)
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
026 decrease » _ decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a sizes » _ sizes (Expand Search)
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Attenuation of spheroid size decrease or MUC5AC increase by hit compounds.
Published 2023“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”
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<i>Trappc9</i> deficient mice show a decrease in brain weight and size.
Published 2020“…<p><b>(A)</b><i>Trappc9</i> deficient mice show a decrease in brain weight in a parent-of-origin manner. …”
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Primary small molecule screen to identify attenuators of CSE-induced decrease in size and increase in MUC5AC.
Published 2023“…Hit compounds at 1 and 10μM concentrations that <b>B)</b> increased spheroid size (swell) or <b>C)</b> decreased MUC5AC staining in the lumen relative to DMSO and CSE 3%-treated bronchospheres. …”
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Supplementary Material for: Decreases in Brain Size and Encephalization in Anatomically Modern Humans
Published 2021“…Over the past 50,000 years, however, both body size and brain mass have decreased but little is known about the scaling relationship between the two. …”
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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