HIV-1 Nef Inhibits Protease Activity and Its Absence Alters Protein Content of Mature Viral Particles by Luiza M. Mendonça (584366)

“…Collectively, our data support the hypothesis that the decreased infectivity typical of <i>nef</i>-deficient viruses is due to an abnormal function of the viral Protease, which is in turn associated with less mature particles being produced and the loss of Integrase content in these particles, and these results may characterize Nef as a regulator of viral Protease activity.…”

Supplementary figures 1-6 from Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling by Dhanya K. Nambiar (3901195)

“…This combination also decreased the expression of PCNA and survivin in DU145 and PC-3 cells. …”

Image 3_Cellulase over lactic acid bacteria in enhancing antioxidant capacity of mulberry silage via phenolic release.tif by Yaya Guo (12794291)

“…Antioxidant assays showed notably higher DPPH and ABTS radical scavenging activities in the C and C_LAB groups. 16S rRNA sequencing revealed reduced bacterial diversity and increased Lactobacillus abundance (96.51%) and decrease Enterobacter abundance (5.12%) in C_LAB. Metabolomics analysis indicated that both C and C_LAB markedly altered phenylpropanoid and polyketide profiles, upregulating antioxidants like Camelliaside B and Quercetin 3-O-xylosyl-rutinoside, and enriching pathways such as flavonoid biosynthesis. …”

Detection and quantitation of cholesterol 27-hydroxylase in THP-1 cells exposed to SC560 by Edwin SL Chan (28334)

“…COX, cyclooxygenase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; SC560, 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazol. ** < 0.01.…”

Aromatic Ring-Fused BODIPY-Based Conjugated Polymers Exhibiting Narrow Near-Infrared Emission Bands by Atsushi Nagai (36896)

“…The photostabilities of the polymers were examined by monitoring decrease of the PL spectra under continuous UV irradiation using a UV lamp under aerobic conditions. …”

Data_Sheet_1_Sex differences and the effect of female sex hormones on auditory function: a systematic review.DOCX by Nada Aloufi (15337069)

“…Finally, the systematic review highlights the need for well-designed and -controlled studies to evaluate the influence of estradiol and progesterone on hearing by consistently including control groups (e.g., age-matched man), using objective tests to measure hormonal levels (e.g., in saliva or blood), and by testing participants at different points across the menstrual cycle.…”

pPplA enhances bacterial aggregation in broth culture. by Bobbi Xayarath (209925)

“…The optical-density at 600nm was monitored at the indicated time points for 1 mL of an overnight culture initially grown in BHI with shaking at 37°C then left statically at RT, where bacterial aggregation is measured as the decrease in the optical-density of the culture supernatant as the bacterial aggregate out of solution. …”

Data_Sheet_1_Impact of Concomitant Impairments of the Left and Right Ventricular Myocardial Strain on the Prognoses of Patients With ST-Elevation Myocardial Infarction.docx by Wei Lai (601813)

“…</p><p>Conclusions: The concomitant decrease of LV and RV strain is associated with a worse long-term prognosis than impaired LV strain alone. …”

Characterization of the sexual development of deletion mutants for spore-enriched proteins. by Mingwei Huang (788799)

“…Panels show the periphery of a spot of a cross on V8 plate for 24h at 25°C. …”

Characterization of the two latent classes of problematic internet users obtained from the Latent Profile Analysis (N = 1,066). by Halley M. Pontes (10268297)

“…Problematic internet use symptom means for each item of the Problematic Internet Use Questionnaire Short-Form (PIUQ-SF-6). …”

Table_1_Enhancing the recovery of human-edible nutrients in milk and nitrogen efficiency throughout the lactation cycle by feeding fatty acid supplements.DOCX by Jonas de Souza (4662913)

“…Two experiments were conducted with grazing Jersey × Holstein dairy cows. In Experiment 1, five dairy cows were used in a 5 × 5 Latin Square design. …”

Dachsous, Fat, Four-jointed, and Hippo regulate <i>Drosophila</i> obesity. by Neha Agrawal (371176)

“…(C) Fly weight upon ubiquitous knockdown of <i>Drosophila dachsous</i>, <i>fat</i>, or <i>fj</i>. Each data point corresponds to the weight of 8 to 10 males normalised to number of flies. …”

Snail1 loss altered cytoskeletal organization and gene expressions in RMG1 cells. by Misako Haraguchi (768459)

“…Snail1 KO1 cells showed a complete loss of Snail1 expression and an increase in E-cadherin, occludin and claudin-1, beta-actin, alpha- tubulin, as well as a decreased in integrin alpha 5 expression. …”

Table_1_Meta-Analysis of the Effect of Exercise on Neuropathic Pain Induced by Peripheral Nerve Injury in Rat Models.DOC by Jia-bao Guo (6840998)

“…For the mechanical withdrawal threshold, rats in the exercised group exhibited significantly higher thresholds than those in the control group, with a MD of 0.91 (95% CI 0.11–1.71), 3.11 (95% CI 1.56–4.66), 3.48 (95% CI 2.70–4.26), 4.16 (95% CI 2.53–5.79), and 5.58 (95% CI 3.44–7.73) at 1, 2, 3, 4, and 5 weeks, respectively. …”

Table_2_Meta-Analysis of the Effect of Exercise on Neuropathic Pain Induced by Peripheral Nerve Injury in Rat Models.DOCX by Jia-bao Guo (6840998)

“…For the mechanical withdrawal threshold, rats in the exercised group exhibited significantly higher thresholds than those in the control group, with a MD of 0.91 (95% CI 0.11–1.71), 3.11 (95% CI 1.56–4.66), 3.48 (95% CI 2.70–4.26), 4.16 (95% CI 2.53–5.79), and 5.58 (95% CI 3.44–7.73) at 1, 2, 3, 4, and 5 weeks, respectively. …”

Diagrams. by Ana-Maria Buga (111779)

“…In control rats, there were only a few BrdU-positive cells, often in a duplex, mitosis-like state (<b>C, D, E</b>). …”

SPRC reduces inflammatory hepcidin activation by inhibiting IL-6/JAK2/STAT3 pathway. by Minjun Wang (508018)

“…<p>(A) SPRC and NaHS markedly decreased serum IL-6 levels induced by LPS (n = 5). …”

Cell proliferation of commercial CRC cell lines treatment combinations. by Heather F. Sinner (7541852)

“…Graphic representations are the mean ± SD plotted as a percentage relative to untreated control; each measurement was performed with 5 replicates. …”

Cell proliferation of PDX-derived CRC cell lines treatment combinations. by Heather F. Sinner (7541852)

“…Graphic representations are the mean ± SD plotted as a percentage relative to untreated control; each measurement was performed with 5 replicates. …”

Increased P-gp levels are associated with diminished drug uptake in drug-resistant MCF-7 cells. by Derek W. Edwardson (4439047)

“…<p>(A) Flow cytometry was used to assess P-gp levels [as expressed by mean fluorescence intensity (MFI) values] for MCF-7 cells at selection doses 8, 9, 10, 11, and 12. …”