Raw data used to generate the graphs shown in Figs 1B, 1E, 2B, 3B, 4B and 5A–5C of representative experiments from three independent biological repeats. by Timilehin Faboro (20175963)

Subjects:

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

scSOX9 induced increased expression of SOX5, SOX9 and collagen II but decreased expression of collagen I and X. by Xiaowei Zhang (6505)

Overexpression of miR-219-5p in glioma cell lines decreased proliferation, anchorage independent growth and migration of glioma cells. by Soumya Alige Mahabala Rao (413479)

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Three Ca_V3.3 variants left-shift the window current, while the A398V completely abolishes the window current. by Yousra El Ghaleb (22075892)

Subjects:

Fig 5 - by Andrea R. Thurman (5286005)

Glu58 and Arg87 minimal distance decreases upon activation. by Maxime Louet (150102)

Resveratrol decreased tumor latency in <i>Sirt1^Y/+</i> mice. by Katherine V. Clark-Knowles (368164)

M344 decreases orthotopic pancreatic tumor growth when used as a treatment alone or in combination with gemcitabine. by Shelby M. Knoche (13833807)

The Karolinska Sleepiness Scale (KSS) is a 9-point Likert scale, ranging from “extremely 1 = alert” to “9 = extremely sleepy–fighting sleep” [44]. by Marcel F. Hinss (14675457)

Compared to vorinostat, M344 decreases pancreatic cancer cell proliferation more effectively for a longer duration. by Shelby M. Knoche (13833807)

Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover by Naoto Hori (767562)

“…In the high-friction regime (η ≳ 10^–5 Pa·s), for both HP and PK, <i>k</i>_F values decrease as 1/η, whereas in the low friction regime, <i>k</i>_F values increase as η increases, leading to a maximum folding rate at a moderate viscosity (∼10^–6 Pa·s), which is the Kramers turnover. …”

PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Inhibition of the V-ATPase by SidK. by Jianhua Zhao (531939)

Subjects:

Predicted steady state distribution of the percent of TDLs in a 1) control animal, 2) following increased in the average residence time of lymphocytes in the lung (20 fold, from 26 seconds to 9 minutes) due to, for example, inflammation in the lung; 3) following a decreased entrance rate of TDLs into lymph nodes and Peyer's patches (20 fold, e.g., by using anti CD62L antibody); 4) following a decreased exit rate of TDLs from lymph nodes and Peyer's patches (5 fold, e.g., using FTY720). by Vitaly V. Ganusov (142019)

Average self-reported physical health ratings before or during the COVID-19 pandemic among individuals who engaged during the pandemic in more than 3 (A), 4 (B), or 5 (C) positive... by Elie Mulhem (22537863)

Determinants of decrease in COVID-19 immunity among vaccinated patients over a 6-month period using univariate analysis and multivariable logistic regression models. by Dalal Nour (18530615)

The shortened version of the Edinburgh Handedness Inventory encompasses 4 items (e.g. writing) scored on a 5-point scale ranging from:” Always right; usually right; both equally; u... by Marcel F. Hinss (14675457)

A R13A point mutation in C4 attenuates CLCuMuV infection. by Asigul Ismayil (5698946)

“…<b>(C)</b> The mutant CLCuMuV carrying C4^R13A (CLCuMuV-C4^R13A), which contains a R13A mutation in <i>C4</i>, showed the decreased viral symptom compared to wild type CLCuMuV. …”