Summary of five key points guiding the Safe Steps evaluation and implementation. by Esario IV Daguman (21474116)

K-fold cross validation accuracy of different models. by Shayla Naznin (13014015)

Subjects:

Fig 5 - by Lingru Ruan (18995544)

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

Efficacy end points. by Youngmin Ko (3333819)

Subjects:

The intensity of thioflavin-T binding-dependent fluorescence of native GAPDH, GAPDH treated with piceatannol (50 μM), GAPDH treated with hydrogen peroxide (3 mM) and GAPDH preincub... by Joanna Gerszon (4732971)

Mutations in p38 MAP kinase components and the mucolipin ortholog CUP-5 suppress the decrease in abundance of RAB-7 in <i>madd-3</i> mutants. by Serena A. D’Souza (2635801)

Distribution of miRs with a greater than two fold-change. by Stephanie L. Samani (17896610)

Subjects:

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing for the iliocostalis muscle. by Christoph Anders (4068499)

Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor by Beatrice Noce (16540800)

Subjects:

Average giving in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

The 5-point summary of CPM dataset. by Gaurav Sandeep Dave (21519884)

Validation accuracy of our custom CNN model with the directional filters over 5 folds. by Salih Furkan Atici (12988243)

Inactivation of one allele of FT5. by Sophia Bigot (16469992)

Survivability is decreased in zebrafish embryos following exogenous treatment with an amino-terminal fragment of nApoE4_1-151. by Madyson M. McCarthy (9238322)

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. by Xiaowen Jiang (8291814)

Capzb2 coimmunoprecipitates with βIII-tubulin in brain lysates and decreases tubulin polymerization in vitro. by David A. Davis (239142)

“…Each point depicted represents the average of 20 OD readings obtained for each Capzb2 concentration examined (0, 0.1, 0.5, 1, and 10 µM) during the interval 180–750 s; <i>R</i>² (correlation coefficient) = 0.99. …”