supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…<p dir="ltr">Supplementary Figure: Identification of osimertinib as an inhibitor of the MYLK4–CDKAL1–SALL2 axis a (left): RT‒qPCR and immunoblotting of RD cells treated with 40 ng/mL epidermal growth factor (EGF) and 2.5 µM osimertinib for 24 h revealed that osimertinib inhibits SALL2 expression in a translation-dependent manner. …”

Table_1_ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer.docx by FenFen Xie (9544523)

“…Emerging evidence has demonstrated that the circadian clock system regulates cell-signaling pathways critical to cancer cell proliferation, survival and metastasis, meaning that it could be a good candidate for TNBC treatment. …”

Sirt1 expression, deletion, and testing FAA in mice lacking Sirt1 in Pomc neurons. by Dina R. Assali (5447489)

“…<p>Immunostaining for Sirt1 in the adult mouse brain reveals a broad neuronal expression pattern: (A) CA1 region of the hippocampus (scale bar indicates 100 microns) and (B) low magnification image of the dorsal hypothalamus (scale bar indicates 500 microns), showing robust Sirt1 expression in the paraventricular nucleus. …”

Yeast glucose consumption, ethanol production and growth rates. by Arne Hagman (433637)

“…On the other hand, the growth rate (in green) is very similar among all <i>Saccharomycotina</i> yeasts (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068734#pone-0068734-g005" target="_blank">figure 5</a> C and D).…”

Data_Sheet_1_Ethanol Inhibits Aflatoxin B1 Biosynthesis in Aspergillus flavus by Up-Regulating Oxidative Stress-Related Genes.docx by Yaoyao Ren (8318712)

“…The suppression of several key aflatoxin genes including aflR, aflD, aflM, and aflP may also be associated with the decreased expression of the global regulator gene veA. …”

Cerebral activation patterns during movement execution in the affected hand for patients versus normal controls and patients versus feigners. by Marije van Beilen (5652724)

“…Note that this Figure also displays activity (not numbered) significant at an uncorrected threshold, to preserve explorative qualities of the study. A: Increased activation (red, t = 3.16 to yellow, t = 7) and decreased activation (blue t = 3.16 to green, t = 6.0) in patients versus normal controls. …”

Table 1_Dietary supplementation with soluble corn fiber improved fecal score, microbiota, and SCFAs in dogs.docx by Donghui Liang (8981447)

“…Microbial diversity analysis showed the addition of SCF to the diets increased the relative abundance of Bacteroidota and Blautia and decreased the relative abundance of Firmicutes, [Ruminococcus]_gnavus_group, and Prevotellaceae_Ga6A1_group; 1% SCF the relative abundance of Prevotella and Blautia (p < 0.05), and the content of acetic acid, valeric acid, and isobutyric acid (p < 0.05) and significantly decreased the content of butyric acid (p < 0.05).…”

Effects of 50 µM stearic acid, oleic acid and linoleic acid on cell death and apoptosis of 3T3L1 preadipocytes. by Ming-Che Shen (629982)

“…(B) Cytotoxicity was significantly increased after 24 hours of treatment with stearic acid (*, p<0.01, compared to control, n = 5). However, it was significantly decreased with 24 hours of oleic acid treatment (#, p<0.01, compared to control, n = 4). …”

Effects of Ananas comosus leaf powder on broiler performance, haematology, biochemistry, and gut microbial population by Md. Mahbubur Rahman (4068862)

“…One hundred male broiler chicks (aged one day) were divided into five groups consisting of four pens as replicates, which were treated with basal diet (normal control); basal diet supplemented with 1, 2, and 3% PLP; or 50 mg/kg of zinc bacitracin (ZnB) as a positive control for 35 days. …”

Astaxanthin protects against hearing impairment in diabetic rats by Serdar Ferit Toprak (14435233)

“…Level of evidence: The level of evidence of this article is 5. This article is an experimental animal and laboratory study.…”

Vascular and ventilatory mechanical responses in three different stages of pulmonary development in the rabbit model of congenital diaphragmatic hernia by Rebeca Lopes Figueira (6015872)

“…CRS and RRS of CDH and E27 were similar and were higher in E25 (p<0.05). MWT was decreased according to the gestational age, was increased in E27V and E30V (p<0.05) and decreased in CDHV (p<0.05), airspace was decreased in E25 and increased in all ventilated groups (p<0.05). …”

Lysine succinylation of <i>Mycobacterium tuberculosis</i> isocitrate lyase (ICL) fine-tunes the microbial resistance to antibiotics by Mingliang Zhou (172233)

“…For the <i>in vitro</i> activity of the purified isocitrate lyase, only K189E mutant showed significantly decreased activity. Crystal structure analysis showed that Lys189 Glu dramatically increased the pKa of Glu188 and decreased the pKa of Lys190, whereas had negligible effect on other residues within 5 Å as well as disruption of the electrostatic interaction between Lys189 and Glu182, which might prevent the closure of the active site loop and cause severe reduction of the enzyme activity. …”

Hypoxia-Induced Modulation of Apoptosis and BCL-2 Family Proteins in Different Cancer Cell Types by Audrey Sermeus (37122)

“…In HepG2 cells that are strongly protected against cell death by hypoxia, hypoxia decreased the abundance of nearly all the pro-apoptotic BCL-2 family proteins while none of them are decreased in A549 cells that are not protected against cell death by hypoxia. …”

Elucidating the Molecular Mechanisms of Hederagenin-Regulated Mitophagy in Cervical Cancer SiHa Cells through an Integrative Approach Combining Proteomics and Advanced Network Asso... by Hao Sun (14095)

Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition - Fig 2 by Ling Zhang (18071)

“…E) Fecal calprotectin is decreased in children to be discharged. Boxplots represent 25th and 75th quartiles, box-midline indicates median and whiskers define top and bottom values within 1.5 times the inter-quartile range (IQR). …”

Global positive effects of climate change on terrestrial soil methane emissions by Huili Feng (11658088)

“…These datasets were grouped into three separate files according to different types of climate manipulation: (i) increased temperature (Datasets S1), (ii) increased precipitation (Datasets S2), (iii) decreased precipitation (Datasets S3). The geographical scope of those research was between −37°25′ N and 69°45′ N latitude, with MAT between <a>−</a>11.5 °C and 26.4 °C and MAP between 158 mm and 2,539 mm. …”

Vertical zonation and functional diversity of fish assemblages revealed by ROV videos at oil platforms in The Gulf by Torquato, F.

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Effect of the support on physicochemical properties and catalytic performance of cobalt based nano-catalysts in Fischer-Tropsch reaction by Ali, Sardar

“…Fischer-Tropsch reaction (FTS) was carried out in a fixed-bed microreactor (220 �C and 1 atm and with H2/CO = 2 v/v, SV of 12 L/g h). …”
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Binding assays and secondary structure models for RNA molecules containing the Com binding sites. by Martyna Nowacka (6635225)

“…(B) EMSA confirmed that the Com binds RNA with </p><p>5ʹ-CC(N)_2-3GAG-3ʹ</p> motif. (C) Secondary structures of Com targets predicted by RNA structure [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0214481#pone.0214481.ref027" target="_blank">27</a>] using reactivity from the SHAPE experiment as pseudo-free-energy constraints for RNA molecule alone (first molecule of each pair) and for the same RNA in the presence of Com (second molecule of each pair). …”

original data.rar by Yongjian Xiong (12099560)

“…<p>Inhibition of ferroptosis in intestinal epithelial <a>cells ameliorates clinical symptom</a> and improves endoscopic presentations in inflammatory bowel disease (IBD). …”