Molecular regulation of miR-378 on the development of mouse follicle and the maturation of oocyte in vivo by Xiao-Feng Sun (149119)

“…The results showed that CMV-miR-378 lentivirus transduction in the mouse ovaries resulted in reduced ovary size, extended oestrous cycle (6-7 d in miR-378 overexpression group and 4–5 dyas in GFP control group) due to continuous oestrum, decreased percentage of oocytes in vitro maturation rate (IVM 60.8% vs. 89.4% in GFP control), increased apoptosis rate (Bax/Bcl2 in mRNA and protein level), decreased expression of genes associated with gap junction, such as connexin 43 (Cx-43) and connexin (Cx-37) and decreased expression of genes associated with follicular development, such as BMP15 and GDF9. …”

Constitutive heterochromatin controls nuclear mechanics, morphology, and integrity through H3K9me3 mediated chromocenter compaction, Manning et al raw data by Gianna Manning (19858309)

“…Nuclear stiffness increases upon loss of H3K9me2 and decreases upon loss of H3K9me3.</b></p><p dir="ltr"><b>Figure 5. …”

Palmitate-induced loss of caveolin-3 from the T-tubule system in the heart. by Catherine J. Knowles (400844)

“…<p><b>A</b>) Localization of caveolin-1 and -3 in confocal images of isolated cardiomyocytes from mice fed standard, MCT or palmitate diet for 12 weeks. …”

Alternative splicing events affecting PTPRC exons 4 to 7. by Charlotte Vandermeulen (11457794)

“…(B) Increased inclusion of exon 4. Decreased inclusion of exon 5 (C), 6 (D) and 7 (E). …”

DataSheet_1_Characterization of 3D heterocellular spheroids of pancreatic ductal adenocarcinoma for the study of cell interactions in the tumor immune microenvironment.docx by Giulio Giustarini (16544991)

“…Further, 4-culture tumor spheroids decreased the concentrations of T-cell chemoattracting cytokines, i.e., CCL4, CCL5, and CXCL9, when compared with the non-cancerous spheroids, revealing a critical immunosuppressive feature of the different types of cells forming the tumor spheroids. …”

Video_7_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Application of Ion Torrent Sequencing to the Assessment of the Effect of Alkali Ballast Water Treatment on Microbial Community Diversity by Masanori Fujimoto (629927)

“…<div><p>The impact of NaOH as a ballast water treatment (BWT) on microbial community diversity was assessed using the 16S rRNA gene based Ion Torrent sequencing with its new 400 base chemistry. …”

Video_3_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Video_1_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Supplementary Figures from Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors by Damir Varešlija (7954046)

“…Images were captured from UCSC Genome Browser. V, vehicle; E, estrogen; A, androstenedione. Figure S9. …”

Image 1_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.tif by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

Video_10_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

DataSheet6_Cost-Effective Transcriptome-Wide Profiling of Circular RNAs by the Improved-tdMDA-NGS Method.pdf by Ashirbad Guria (12539992)

“…<p>Covalently closed circular RNAs are neoteric to the eukaryotic family of long non-coding RNAs emerging as a result of 5′–3′ backsplicing from exonic, intronic, or intergenic regions spanning the parental gene. …”

Widespread cDNA synthesis artifact in long reads. by Amoldeep S. Kainth (17291225)

“…<p><b>A.</b> Plot showing enrichment of primer 1 at the 5’ end and the reverse complement of primer 1 at the 3’ end of artifactual reads. …”

Table 3_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.xlsx by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

DataSheet1_Cost-Effective Transcriptome-Wide Profiling of Circular RNAs by the Improved-tdMDA-NGS Method.PDF by Ashirbad Guria (12539992)

“…<p>Covalently closed circular RNAs are neoteric to the eukaryotic family of long non-coding RNAs emerging as a result of 5′–3′ backsplicing from exonic, intronic, or intergenic regions spanning the parental gene. …”

DataSheet2_Cost-Effective Transcriptome-Wide Profiling of Circular RNAs by the Improved-tdMDA-NGS Method.PDF by Ashirbad Guria (12539992)

“…<p>Covalently closed circular RNAs are neoteric to the eukaryotic family of long non-coding RNAs emerging as a result of 5′–3′ backsplicing from exonic, intronic, or intergenic regions spanning the parental gene. …”

Table_2_Preliminary study based on methylation and transcriptome gene sequencing of lncRNAs and immune infiltration in hypopharyngeal carcinoma.xlsx by Kainan Wu (15353437)

“…In the immune cell infiltration analysis, B cell memory was significantly elevated in cancer tissue, while γδT cell amount was significantly decreased.</p>Conclusion<p>m6A modification of lncRNAs might be involved in HSCC pathogenesis. …”

Table_4_Preliminary study based on methylation and transcriptome gene sequencing of lncRNAs and immune infiltration in hypopharyngeal carcinoma.xlsx by Kainan Wu (15353437)

“…In the immune cell infiltration analysis, B cell memory was significantly elevated in cancer tissue, while γδT cell amount was significantly decreased.</p>Conclusion<p>m6A modification of lncRNAs might be involved in HSCC pathogenesis. …”

Video_2_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”