Deletion of Dclk1 exacerbates colonic barrier dysfunction following DSS treatment. by Dongfeng Qu (455807)

“…Western blot analysis of tight junction and adherens junction proteins demonstrated a decrease in Claudin-1, Claudin-7, and E-cadherin in the Villin^Cre;Dclk1^f/f mice after DSS treatment; <b>D.…”

Cryopreservation Causes Genetic and Epigenetic Changes in Zebrafish Genital Ridges by Marta F. Riesco (425309)

“…Our results indicated that cryopreservation produced a decrease in most of the zebrafish studied transcripts (<i>cxcr4b, pou5f1, vasa</i> and <i>sox2</i>) and upregulation of heat shock proteins (<i>hsp70, hsp90</i>). …”

Figure 7 by Ana Carmena (274350)

“…</p> <p>Lane 4, 5 and 6: The addition of increasing amounts of Dsh leads to a decrease in the amount of *Ras^V12 co-IP with Cno.…”

Chromosome Segregation Analysis in Human Embryos Obtained from Couples Involving Male Carriers of Reciprocal or Robertsonian Translocation by Ahmet Yilmaz (132195)

“…Involvement of non-acrocentric chromosome(s) or terminal breakpoint(s) in reciprocal translocations was associated with an increase in the percent of embryos consistent with adjacent 1 but with a decrease in 3∶1 segregation. Similar results were obtained in the analysis of nontransferred embryos donated for research. 3∶1 segregation was the most frequent segregation type in both day 3 (31%) and spare (35%) embryos obtained from carriers of t(11;22)(q23;q11), the only non-random REC with the same breakpoint reported in a large number of unrelated families mainly identified by the birth of a child with derivative chromosome 22. …”

Comparison of mutp53 binding to scDNA and linDNA by EMSA. by Marie Brázdová (394463)

“…<p>Mutp53 proteins R175H, G245S, R248W, R249S, R273H, R273C, R282W and wtp53 were bound to scDNA (pBSK, 200 ng, A), linDNA (linBSK, 200 ng, B) and to linDNA with p53CON sequence (linPGM1, 200 ng, C) in p53/DNA molar ratios 1, 2, 3 and 5 (for R175H only) at 25°C; EMSA was performed at 4°C. …”

Image_1_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.JPEG by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Zooming in: Structural Investigations of Rheologically Characterized Hydrogen-Bonded Low-Methoxyl Pectin Networks by Bradley W. Mansel (1514149)

Image_2_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.png by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Incidence of stalk rots in corn hybrids influenced by sowing time and nitrogen rates by Juliano Berghetti (6515036)

“…A decrease in the incidence of stalk rot was observed in the hybrid AG9025 PRO3 as nitrogen rates increased, but this behavior was not clearly observed in the hybrid 30F53 VYH.…”

Chronic intermittent ethanol (CIE) exposure alters the time course of STDP. by Sven Kroener (321008)

“…<p>EPSPs were induced by focal stimulation close to basal dendrites of the recorded neuron in layers V/VI. Pairing an EPSP with a burst of postsynaptic action potentials lead to consistent increases in all 3 treatment groups (control, CIE no withdrawal, and CIE followed by 7 days of withdrawal) at 20–30 minutes post pairing. …”

Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2DM and NGT Subjects by Xi Chen (35903)

“…Following DAPA, EGP increased in both T2D and NGT from baseline to 240 minutes, while there was a significant time-related decrease after placebo in T2D. …”

Effects of Light Intensity on Growth, Anti-Stress Ability and Immune Function in Yellow Feathered Broilers by YL Guo (5160098)

“…There was a linear effect for T-AOC(p=0.002), GSH-Px(p≤0.047), MDA (p=0.003), H/L(p≤0.014), ANAE+ (p≤0.044), and antibody titer (p≤0.021) with T-AOC, GSH-Px, ANAE+, and antibody titer increased significantly as light intensity decreased, whereas MDA and H/L were decreased with the decrease in light intensity. …”

Clinical and virological profiles of chimeric strain pony infections. by Jodi K. Craigo (421284)

“…Febrile episodes are defined by achieving a combination of two-three features such as: rectal temperature above 39°C in conjunction with thrombocytopenia (platelet decrease of ≥70,000/µl of whole blood), EIAV viral load ≥10⁵ as well as other clinical signs of EIA. …”

Different cell fate in aortic valves between male and female RHD patients. by Feng Xiao (27219)

“…GAPDH expression is used to normalize the expression level. (H): Decreased expression of autophagy genes, BECN1 and LC3A, in aortic valves of female patients. n = 8 patients/group for TUNEL assay and Ki67 staining, n = 5 for RT-qPCR, *<i>p</i> < 0.05, **<i>p</i> < 0.01, scale bar = 100μm.…”

Aquaponic Systems for Sustainable Resource Recovery: Linking Nitrogen Transformations to Microbial Communities by Sumeth Wongkiew (5851964)

“…Here, we employed quantitative polymerase chain reactions and next-generation sequencing to evaluate the bacterial communities and their links to nitrogen transformations for improving NUEs in four bench-scale plant-based floating-raft aquaponics (pak choi, lettuce, chive, and tomato) and three pH levels (7.0, 6.0, and 5.2). Low relative abundance of nitrifiers in plant roots and biofilters suggested nitrogen loss, which decreased NUE in aquaponics. …”

Bidirectional “switch” in TRIM29 regulation from normal epithelium to the respective carcinomas. by Ayelet Avraham (539937)

“…<p>TCGA data analysis: (<b>A</b>) TRIM29 promoter methylation (average of 5 Illumina probes, <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091805#pone.0091805.s005" target="_blank">Table S4B</a></b>) in normal and in cancer tissues. …”

Data_Sheet_2_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications by Matthew Courtney (3396641)

“…This work demonstrates a droplet microfluidic platform that has the potential to significantly reduce the reagent consumption and shorten the reaction and analysis time by utilizing nanoliter-sized droplets as a replacement of wells. …”

Image 1_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Rapid Global Expansion of Invertebrate Fisheries: Trends, Drivers, and Ecosystem Effects by Sean C. Anderson (228180)

“…New fisheries have developed increasingly rapidly, with a decrease of 6 years (3 years) in time to peak from the 1950s to 1990s. …”