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621
Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter...
Published 2022“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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622
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623
Quercetin Loaded Silica and Gold - Coated Silica Nanoparticles: Characterization, Evaluation and Comparison of Their in vitro Characteristics
Published 2023“…The mean particle size increased after coating and QC loading with a polydispersity index (PDI) between (∼ 0.2 - 0.6) and negative zeta potential (-13 to - 15 mV). …”
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624
Barriers and Motivators of Appropriate Antibiotic Prescription at PHCC in Qatar: Perspective of Physicians and Pharmacists
Published 2020“…Antimicrobial resistance (AMR) is a serious public health problem of global concern. …”
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625
Barriers and motivators of appropriate antibiotic prescription at PHCC in Qatar: perspective of physicians and pharmacists
Published 2020“…Antimicrobial resistance (AMR) is a serious public health problem of global concern. …”
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626
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells.
Published 2020“…Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. …”
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627
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629
Effect of bond enhancement using carbon nanotubes on flexural behavior of RC beams strengthened with externally bonded CFRP sheets
Published 2022“…A nonlinear finite element (FE) model was built, validated, and used to study the effect of various parameters on the strengthening efficiency of CNTs-modified CFRP. …”
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630
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631
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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632
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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633
Warming up for athletic events
Published 1985“…If the results of the research in our field seem to be controversial at this time, that probably is due to the fact that each study has tried to find the answer to the question from a different point of view with different factors involved (24).…”
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634
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635
Repositioning of the global epicentre of non-optimal cholesterol
Published 2020“…These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. …”
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636
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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Published 2017“…Study quality was assessed using a National Institutes of Health assessment tool. …”
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639
The influence of aeration scheme and aeration rate on the permeate flux for wastewater treatment using membrane bioreactors: Experimental and artificial neural network modeling
Published 2021“…Furthermore, a continuous and pulsed aeration scheme (5 min on and 5 min off) was tested. …”
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640
An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH4-CO2-H2S
Published 2021“…The model predictions for the solidification points of 5 different mixtures were within the acceptable error when compared to the experimental data available in the literature. …”
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