The VPS C846G mutation decreases the stability of VPS11 protein. by Jinglan Zhang (401545)

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

Decreased projections to LP in <i>Brn3b</i> mutants occur postnatally. by Hyoseo Lee (17419987)

“…(<b>H</b>) Quantification (1.00 ± 0.09 for control, 0.45 ± 0.03 for cKO); unpaired two-tailed Student’s <i>t</i> test (mean ± SEM; <i>p</i> < 0.0001 [****] at P4/P5; <i>p</i> = 0.0004 [***] at P8/P9; <i>p</i> = 0.0012 [**] at P12/P13). …”

Inhibition of NFAT activity with CsA and INCA-6 decreases CASQ2 mRNA synthesis in neonatal cardiomyocytes. by Rafael Estrada-Avilés (4424278)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

Y-27632 collaborated with BA to attenuate the increase in the integrity and decrease in the permeability of epithelial barrier injury induced by LPS in Caco2 monolayers. by Luqiong Liu (11537092)

D-4F and L-5F improves blood glucose. by Kristine C. McGrath (8269155)

CD5-2 decreases established CCM lesions in the hindbrain of <i>Ccm2</i>^<i>ECKO</i> mice and lesions in the retina of <i>Ccm2</i>^<i>ECKO</i> mice. by Jia Li (160557)

M2 macrophages decrease alkaline phosphatase activity through Wnt signalling pathways. by Jesús Cosín-Roger (123861)

Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver. by Nicole K. Polinski (10947787)

“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”

PGC-1β KO mice show a specific decrease in Mfn2 expression in skeletal muscle. by Marc Liesa (35879)

AS021 activity and Satb2 expression decrease within deep layers at postnatal stages. by Kensuke Tashiro (193459)

“…(E–G″′) Immunostaining for Satb2 (red), Ctip2 (blue), and βgal (green) in coronal sections of P2 AS021-lacZ brains reveals a strong decrease of Satb2 staining specifically in deep layers. …”

I348T increases H77 entry dependency on SR-BI, while T385P decreases H77 entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

Parkin decreases total and cell surface expressed Ca_V2.2 channels. by Lizbeth Grimaldo (4476871)

Ex vivo exposure with different genotypes of HCV strains induced genotype-specific decrease of NKG2D expression on CD56+CD3+ lymphocytes. by Po-sung Chu (549427)

Subjects:

Suppression of APN/CD13 expression by siRNA induced a marked decrease in migratory potential of ES-2 cells by Mikio Terauchi (35139)

“…D; The level of migration of ES-2 cells transfected with si-CD13 relative to the control was 33%. …”

Chronic FIV infection is associated with decreased lymphocyte numbers in Lm challenged LN. by Rita D. Simões (160722)

MEK1/2 inhibition promotes invasive-opposing leading edge lamellipodial structures in 3-D by increasing localised Rac1 activity and decreasing localised RhoA activity. by Joseph H. R. Hetmanski (2656735)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Casein kinase 1.2 depletion decreases ZC3H11 phosphorylation. by Igor Minia (399074)

“…Procyclic cells expressing in situ tagged V5-CK1.2, with a tetracycline-inducible stem-loop RNAi construct, were induced with tetracycline (200g/ml). …”