Dephosphorylation of AMPK substrate i.e. acetyl CoA carboxylase (ACC) initiates neuritogenic effect of SIM. by Varshiesh Raina (457377)

“…SIM led to a significant (<i>p</i> < 0.05^*) increase in pACC (Ser-79) levels at 2 hrs which was followed by a gradual decrease. …”

Schematic of Unstable Multiple-Peak Solution in a Mass Conserved Reaction–Diffusion System by Mikiya Otsuji (75660)

“…The u-form molecules convert v-form molecules into u-form, and this positive feedback is so strong under the condition where ∂<i>P_e</i>/∂<i> N̄</i> < 0 [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030108#pcbi-0030108-b048" target="_blank">48</a>] that infusion of molecules into the space causes a decrease in v-form molecules. …”

Pulmonary function tests – an easy selection method for respiratory-gated radiotherapy in patients with left-sided breast cancer by Mari H. B. Hjelstuen (3642640)

“…</b> Dose to the heart (V25Gy and D_mean) decreased with increasing TLV-CT. …”

Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review by Stephanie Zakhour (8527005)

Depth distribution of exchangeable aluminum in acid soils: A study from subtropical Brazil by Diego Oliveira Rabel (5527358)

Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review by Stephanie Zakhour (8527005)

Data_Sheet_1_Hurricane Risk Assessment of Petroleum Infrastructure in a Changing Climate.pdf by Majid Ebad Sichani (9130160)

“…The results reveal that either an increase in mean sea level or a decrease in storm forward speed increases the maximum water elevations in the HSC for storms that produce maximum wind setup in Galveston Bay (FEMA 33 and FEMA 36), resulting in larger economic loss estimates. …”

Table_1_Safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of WBP216, a novel IL-6 monoclonal antibody, in patients with rheumatoid arthritis: A phase Ia random... by Xiaomei Leng (614420)

“…</p>Methods<p>In this double-blind, placebo-controlled, SAD, phase Ia study, patients with RA were randomized in a 3:1 (Group A1, 10 mg) and 6:2 (Group A2, 30 mg; Group A3, 75 mg; Group A4, 150 mg; Group A5, 300 mg) ratios to receive either ascending doses of WBP216 or placebo subcutaneously. …”

EHV-1 induces platelet activation in equine platelet-rich plasma in a concentration-dependent manner. by Tracy Stokol (718195)

“…RacL11 induced slightly stronger microvesiculation than Ab4, with a decrease in P-selectin expression at the higher PFU/cell of 1 and 5. * p < 0.001 for P-selectin and p = 0.002 for PDMP versus RK, 0.01 and 0.1 PFU/cell for each virus strain (except Ab4 at 0.5 PFU/cell was not significantly different from RK). ** p < 0.001 versus Ab4.…”

The optimal asset allocation between the S&P500 index and a risk-free asset as a function of the risk-free interest rate <i>r</i>_<i>f</i>. by Haim Levy (252011)

“…The bold line shows the optimal allocation to the stock index for a PT investor with the parameters in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0248904#pone.0248904.ref023" target="_blank">23</a>]: <i>α</i> = <i>β</i> = 0.88, <i>λ</i> = 2.25 given by <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0248904#pone.0248904.e007" target="_blank">Eq 5</a>. …”

KDM1 revealed typical electrophysiological features of the K_in-a subclade. by Anda L. Iosip (9749747)

“…The measured I_SS were normalized to −150 mV and 100 mM K⁺ at pH 4 (<i>n</i> = 4; mean ± SD). …”

A novel second-generation platinum derivative and evaluation of its anti-cancer potential by Habibe Yilmaz (4865200)

Intrinsic and extrinsic fluorescence spectroscopy of the protease 1147. by Hossein Tarrahimofrad (9016994)

Pulmonary function tests of mutant mice with reduced bioavailable VEGF indicate a restrictive lung disease. by Minna M. Wieck (849372)

“…Data are expressed as mean ± SEM. (B, C) Mutant mice also demonstrated a 30% decrease in hysteresis and compliance. …”

Heart graft rejection in Lew.1a recipients is significantly influenced by the presence of NK cells. by Oliver Beetz (6786137)

“…Of note, NK cell depletion caused a decrease of NKR-P1A⁺ (NK cells and NKT cells) cells below the baseline of syngeneic controls whereas the NKR-P1A/B⁺ (NK cells, NKT cells and Monocytes) cells were unaffected by the depletion (grey arrows), indicating abundant infiltration of NKR-P1B⁺ monocytes. …”

Inequalities in Alcohol-Related Mortality in 17 European Countries: A Retrospective Analysis of Mortality Registers by Johan P. Mackenbach (147412)

“…<div><p>Background</p><p>Socioeconomic inequalities in alcohol-related mortality have been documented in several European countries, but it is unknown whether the magnitude of these inequalities differs between countries and whether these inequalities increase or decrease over time.</p><p>Methods and Findings</p><p>We collected and harmonized data on mortality from four alcohol-related causes (alcoholic psychosis, dependence, and abuse; alcoholic cardiomyopathy; alcoholic liver cirrhosis; and accidental poisoning by alcohol) by age, sex, education level, and occupational class in 20 European populations from 17 different countries, both for a recent period and for previous points in time, using data from mortality registers. …”

The interaction between tonic GABA_AR signaling and glutamatergic activity. by Michelle Day (11617621)

“…Increasing depolarization (2–3 mV to 10⁻⁵ S/cm² density) was accompanied by a dendritic spike in response to a glutamatergic input that was subthreshold in the absence of tonic GABA activation. …”

Personalized Prediction of Lifetime Benefits with Statin Therapy for Asymptomatic Individuals: A Modeling Study by Bart S. Ferket (107294)

“…In 2,428 participants (mean age 67.7 y, 35.5% men), statin therapy increased total life expectancy by 0.3 y (SD 0.2) and CVD-free life expectancy by 0.7 y (SD 0.4). …”

A systematic review and meta-analysis of preclinical trials testing anti-toxin therapies for <i>B</i>. <i>anthracis </i>infection: A need for more robust study designs and results by Wanying Xu (3765427)

“…Across all agents and species, agents decreased RR [0.64(0.52,0.79); I² = 5.3%, p = 0.39].…”

The distribution of Ephemeroptera, Plecoptera and Trichoptera in a Norwegian alpine catchment in relation to environmental gradients by Nina Kristine S. Helland (21584459)