Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease by Elena-Raluca Nicoli (2577265)

<i>In silico</i> analysis of 2FN2 phosphorylcholine binding site. by Edith Serrano (791292)

“…<p>The size of PC binding site 2 is reduced from (A) RSVP20 (BSP5b) to (B) murine BSPH1 and from the latter to (C) murine BSPH2. …”

Schematic representation of the TRA/TRD locus use. by Florence Thuderoz (366862)

“…A distal V gene is very rarely rearranged with proximal J genes because of the high recombination frequency between proximal V and J genes, leading to the proximal J genes deletion. 1) the first step governing the TRA/TRD locus utilization is defined by the opening of the most proximal V-J region, 2) According that T cells can undergo 1 to 3 secondary rearrangements, the second step giving the V and J accessible windows, is defined by the opening speeds of V and J regions. …”

Supplementary Material for: Effect of Conventional Medical Therapy or Laparoscopic Sleeve Gastrectomy on Urinary Albumin in Japanese Subjects with Severe Obesity: An Observational... by Watanabe Y. (4129684)

Data_Sheet_1_New Insights Into the Relationship Between Drought and Mental Health Emerging From the Australian Rural Mental Health Study.docx by Tuyen T. Luong (11369262)

“…These effects were maintained after controlling for demographic, social, and environmental factors. We also found that while psychological distress decreases in the later stages of drought, this does not necessarily mean people have good mental health because, for example, factors such as life satisfaction decreased as drought persisted. …”

Data_Sheet_1_New Insights Into the Relationship Between Drought and Mental Health Emerging From the Australian Rural Mental Health Study.docx by Tuyen T. Luong (11369262)

“…These effects were maintained after controlling for demographic, social, and environmental factors. We also found that while psychological distress decreases in the later stages of drought, this does not necessarily mean people have good mental health because, for example, factors such as life satisfaction decreased as drought persisted. …”

Time evolution of parallel (left) and anti-parallel (right) Phe-Nap-ⁱPr arylamide conformations. by Jonathan C. Fuller (141611)

“…<p>a) the number of intermolecular pairs of atoms between <i>h</i>DM2 and the ligand that are within 3.5 Å for parallel conformations; b) the number of intermolecular pairs of atoms between <i>h</i>DM2 and the ligand that are within 3.5 Å for anti-parallel conformations; c) difference in protein-arylamide center of mass distance (Å) from a minimized parallel starting conformation; and d) difference in protein-arylamide center of mass distance (Å) from a minimized anti-parallel starting conformation. …”

Data_Sheet_1_Are there effects of light exposure on daytime sleep for rotating shift nurses after night shift?: an EEG power analysis.docx by Soonhyun Yook (10769833)

“…We also observed that light exposure during daytime sleep could additionally decrease N2 sleep spindle activity and N3 waves in the last sleep cycle.…”

Sustainable mobility at the EU level – in the new transport white paper by Tamas Fleischer (409919)

“…Funded by the European Commission in FP7. Szentendre, Hungary, 5/6 May 2011</p> <p>The main message of the contribution in four points:</p> <p>(1) The environmental targets for 2050 (sixty percent emission decrease, oil dependence decrease) are based on a very progressive vision, clear target.…”

Model for the Differentiation of the HMS. by Caleb Gonzalez (270214)

“…<p>(A) We suggest that differentiation of the HMS results from the convergence of three events: acquisition of a DNA double-strand break (DSB) or double-strand end (DSE, one end of a DSB); induction of the SOS DNA-damage response; and induction of the RpoS general stress-response (modified from Figure 5 in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000208#pgen.1000208-Galhardo1" target="_blank">[2]</a>). …”

Examples demonstrating instances where the minimum number of mt protein-coding (PC) genes is either apparent or ambiguous. by Justin C. Havird (507301)

“…In these cases, the minimum number of genes that statistically recreated the “supergene” topology was chosen (e.g., a single gene, NAD5, for Haplorrhini). This alternative trend was atypical of the data (6.5% and 7.0% of lineages when utilizing amino acid and nucleotide data, respectively). …”

Global divergent responses of soil heterotrophic respiration to nitrogen deposition by Peng Guo (13816147)

“…Δ<i>R</i>_H significantly increased in alkaline soils (pH > 7.5) but decreased in acidic soils (pH < 5.5). Furthermore, Δ<i>R</i>_H significantly increased in soils with high total organic carbon (TOC > 15 g/kg) or low available N contents (NH4+ < 19 mg/kg or NO3− < 15 mg/kg), but decreased in soils with high total N (TN > 11 g/kg). …”

Endogenous BDNF and TrkB levels in retina and SC at various time points after ONC. by Eline Dekeyster (825249)

“…<p>(A) In the retina, the total BDNF levels, analyzed via ELISA, rise upon ONC, reaching a peak at 3 to 5 d, attenuating afterwards. …”

Smooth muscle differentiation and Notch target genes are down regulated in Notch2 and Notch2/Notch3 double mutants. by Qingqing Wang (141110)

“…Notch signaling target gene Heyl shows a robust decrease at E10.5 and E11.5 in the <i>Notch2^−/− (N2^−/−;N3^+/+)</i> and <i>Notch2^−/−;Notch3^−/− (N2^−/−;N3^−/−)</i> yolk sacs, while Hey2 shows a slight decrease and Hes1 expression is unaffected in the mutant genotypes. …”

Effect of RNAi depletion of selected hits on lipid droplet formation and TOR pathway activation. by Vangelis Kondylis (229490)

“…Red and blue columns indicate proteins whose depletion leads to a significant decrease or increase in the number of lipid droplets (marked with double asterisk; p<0.05). …”

Lack of oligodendrocytes after DTA-mediated ablation of <i>C1ql1</i>-expressing OPCs. by Shayan Moghimyfiroozabad (19066182)

“…Scale bars = 100 μm. Quantification shows a massive decrease in OL density in the <i>C1ql1</i>^<i>pos</i> OPC-ablated brains. …”

Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Lifespan was measured in three replicates comprising an average of 103 worms per condition. Data is presented as mean lifespan (columns 1–4), change mean lifespan in comparison to an empty vector RNAi control (column 5), or as the change in the extension of lifespan induced by each long-lived mutant (columns 6–8; for clarity, only decreases >15% are shown). …”

Supplementary Material for: Role of 1α,25-Dihydroxyvitamin D₃ in Adipogenesis of SGBS Cells: New Insights into Human Preadipocyte Proliferation by Felicidade I. (3683905)

“…Treatment with 100 nM 1,25(OH)₂D₃ also decreased MTT absorbance and the lipid concentration. …”

Table_1_Forming Olivine Phenocrysts in Basalt: A 3D Characterization of Growth Rates in Laboratory Experiments.xlsx by Adrien J. Mourey (7870853)

“…Growth rates decrease faintly with time, accompanying transitions between skeletal/hopper and more polyhedral morphologies. …”

Data_Sheet_1_Forming Olivine Phenocrysts in Basalt: A 3D Characterization of Growth Rates in Laboratory Experiments.docx by Adrien J. Mourey (7870853)

“…Growth rates decrease faintly with time, accompanying transitions between skeletal/hopper and more polyhedral morphologies. …”