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66721
Combinatorial treatments result in sensitizing ERα-negative cells towards E2 and 4-hydroxytamoxifen (4-OHT) treatments.
Published 2016“…MCF-7 cells when treated with E2 (ligand activator) and 4-OHT (antagonist) for 48 h showed a similar responsiveness. Res 15, resveratrol 15 μM; Ptero 5, pterostilbene 5 μM; Combination, 15 μM resveratrol and 5 μM pterostilbene in combination. …”
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66722
Supplemental Figure S1: Prolonged Recovery
Published 2021“…Arterial [H<sup>+</sup>] in both animals followed the same temporal changes, whereby at 72h there was a progressive increase in [H<sup>+</sup>] from 24h values that was followed by a progressive decrease by 5 days (<b>B</b>). …”
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66723
Table_1_Evolving growth hormone deficiency: proof of concept.docx
Published 2024“…</p>Methods<p>We performed a retrospective chart review of children who presented for short stature (height less < 2SD for mean/mid-parental height) and/or growth failure (sustained growth velocity < 0 SD) to pediatric endocrinology at Mount Sinai Kravis Children’s Hospital, New York and who had 2 GSTs. …”
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66724
Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases
Published 2015“…<div><p>By means of introgressing a loss-of-function mutation in the <i>p22phox</i> gene from the Matsumoto Eosinophilia Shinshu (MES) rat to stroke-prone spontaneously hypertensive rats (SHRSP), we constructed the SHRSP-based congenic strain lacking the P22PHOX expression (i.e., lacking NADPH oxidases [NOX] activities) (SHRSP.MES-<i>Cyba</i><sup><i>mes</i></sup>/Izm; hereafter referred to as SP.MES). …”
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66725
The Effect of Aerobic Exercise on Intrahepatocellular and Intramyocellular Lipids in Healthy Subjects
Published 2013“…Visit 2 comprised the assessment of hepatic and peripheral insulin sensitivity by a two-step hyperinsulinaemic euglycaemic clamp. …”
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66726
Table 1_Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021.docx
Published 2025“…Background<p>Esophageal cancer (EC) is a major global health issue characterized by high morbidity and mortality rates, with a notably low five-year survival rate. …”
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66727
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66728
The change in the plasma concentration of active ingredient depends on drug type.
Published 2020“…In this stage, the plasma concentration of an active ingredient is decreased step by step. However, in the case of a prodrug, after absorption and metabolism, the plasma concentration of an active ingredient appears, and the next steps are the same as those of the active drug.…”
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66729
Table_1_Different functional lung-sparing strategies and radiotherapy techniques for patients with esophageal cancer.xlsx
Published 2022“…The 2F-VMAT had higher PTV conformability and homogeneity and decreased FL-D<sub>mean</sub>, V<sub>5</sub>-<sub>20</sub> and Lungs-D<sub>mean</sub>, V<sub>5</sub>-<sub>10</sub> but correspondingly increased spinal cord-D<sub>mean</sub> compared with those of the 5F-IMRT planning (P< 0.05).…”
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66730
DataSheet_1_Different functional lung-sparing strategies and radiotherapy techniques for patients with esophageal cancer.docx
Published 2022“…The 2F-VMAT had higher PTV conformability and homogeneity and decreased FL-D<sub>mean</sub>, V<sub>5</sub>-<sub>20</sub> and Lungs-D<sub>mean</sub>, V<sub>5</sub>-<sub>10</sub> but correspondingly increased spinal cord-D<sub>mean</sub> compared with those of the 5F-IMRT planning (P< 0.05).…”
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66731
Impact of alternative assumptions on life expectancy.
Published 2010“…Depending on the baseline CD4 cell count, life-expectancy was increased by 14.8 to 30.9 months with no late failure (green), and was decreased by 2.8 to 6.6 months with 1.5-fold increase in late failure (orange), and by 5.1 to 11.0 months with a 2-fold increase in late failure (red). …”
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66732
Reduced Dopamine Release in the Striatum of <i>DAT-Ret<sup>lx/lx</sup></i> Mice
Published 2013“…There is a further significant decrease in the homozygous <i>DAT-Ret<sup>lx/lx</sup></i> mice due to the lack of Ret (<i>n</i> = 5 per genotype, <i>p</i> < 0.05, Student <i>t</i>-test). *, <i>p</i> < 0.05; **, <i>p</i> < 0.01 (Student <i>t</i>-test). …”
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66733
table_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX
Published 2018“…The decrease in maternal behavior was significantly correlated with a decrease in cognition. …”
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66734
CXCL12-induced migration via AKT is reduced by LPS treatment.
Published 2015“…<p>A) RPMI 8226 cells were stimulated with 100 ng/mL CXCL12 for 5 minutes in the presence or absence of 10 ng/mL LPS. …”
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66735
EFFECT OF WATER DEFICIT AND ABSCISIC ACID ON PHOTOSYNTHETIC AND ANTIOXIDANT METABOLISM IN SEEDLINGS OF Calophyllum brasiliense (CAMBESS.)
Published 2019“…The decrease in stomatal conductance was accompanied by a decrease in photosynthetic and transpiration rates, but seedlings treated with 10 µM ABA presented a higher photosynthetic rate than the remaining treatments under water deficit. …”
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66736
Do Irrigation Solutions Influence the Bond Interface Between Glass Fiber Posts and Dentin?
Published 2019“…Ninety single-rooted human teeth were submitted to endodontic treatment and divided into five groups, according to irrigation solutions: distilled water, 5.25% NaOCl, 25% polyacrylic acid, 2% chlorhexidine, and 23 ppm Ag NP dispersion. …”
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66737
table_2_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX
Published 2018“…The decrease in maternal behavior was significantly correlated with a decrease in cognition. …”
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66738
Image_3_Effect of mastectomy on gut microbiota and its metabolites in patients with breast cancer.tif
Published 2024“…</p>Conclusion<p>Our study found that breast cancer surgery significantly altered gut microbiota composition and metabolites, with a decrease in beneficial bacteria and an increase in potentially harmful bacteria. …”
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66739
Image_1_Effect of mastectomy on gut microbiota and its metabolites in patients with breast cancer.TIF
Published 2024“…</p>Conclusion<p>Our study found that breast cancer surgery significantly altered gut microbiota composition and metabolites, with a decrease in beneficial bacteria and an increase in potentially harmful bacteria. …”
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66740
Global Transcriptional Responses of the Toxic Cyanobacterium, <i>Microcystis aeruginosa</i>, to Nitrogen Stress, Phosphorus Stress, and Growth on Organic Matter
Published 2013“…There was also a significant decrease in the transcription of the microcystin synthetase gene set under low N and a significant decrease in microcystin content per <i>Microcystis</i> cell demonstrating that N supply influences cellular toxicity. …”