Supplementary material: Evaluation of emerging NASH therapies: the impact of treatment efficacy profiles on long-term health outcomes by William Herring (18495130)

“…Hypothetical efficacy profiles were defined affecting resolution (100%-increase), fibrosis improvement (100% increase), or fibrosis worsening (50% decrease). <b>Results:</b> For the SoC, 10-year LRC rates increased with baseline fibrosis stage (F1: 3.0%; F2: 9.8%; F3: 27.2%; F4/CC: 64.9%). …”

Typical example of shift in orientation preference and response modulations. by Narcis Ghisovan (94543)

“…<p>A: The first 12 min adaptation displaces the preferred orientation of the cell by 15.5° toward the adapting stimulus. …”

CircRNA sequencing data. by Yonghui Gao (102566)

“…Furthermore, we demonstrated that circRNA-407 can act as a sponge of aal-miR-9a-5p to promote the expression of its target gene <i>Foxl</i> and eventually regulate ovarian development. …”

Primers and oligo used in this study. by Yonghui Gao (102566)

“…Furthermore, we demonstrated that circRNA-407 can act as a sponge of aal-miR-9a-5p to promote the expression of its target gene <i>Foxl</i> and eventually regulate ovarian development. …”

Self-report of psychological symptoms in hypoparathyroidism patients on conventional therapy by Amanda J. Arneiro (5256824)

“…It has been demonstrated that these patients may also present psychiatric symptoms and decrease of quality of life. The aims of this study were to evaluate the presence of psychopathological symptoms in a cohort of patients with hypoparathyroidism and compare to a control group. …”

Self-report of psychological symptoms in hypoparathyroidism patients on conventional therapy by Amanda J. Arneiro (5256824)

“…It has been demonstrated that these patients may also present psychiatric symptoms and decrease of quality of life. The aims of this study were to evaluate the presence of psychopathological symptoms in a cohort of patients with hypoparathyroidism and compare to a control group. …”

Chp function is required for epibolic movements. by Hwee Goon Tay (250690)

“…Rescue of the phenotype was performed by co-injecting Chp MO 1/2 with WT Chp (Zf) mRNA. Co-injection of 25 pg Chp mRNA with 5 ng Chp MO1/2 efficiently reduced the number of yolk plug defects at 8 hpf. …”

Interdependence of Non-Protein Thiols and Metronidazole Toxicity by David Leitsch (33135)

“…Cells were either treated with 50 μM of metronidazole (left) or azomycin (right) for 2 h under anaerobic (0% O₂ and 18% CO₂), microaerophilic (5% O₂ and 8% CO₂), and aerobic (21% O₂ and 0.4% CO₂) conditions. …”

Data Sheet 1_Body position influence on cerebrospinal fluid volume redistribution inside the cranial and spinal CSF compartments.pdf by I. Strbačko (20633240)

“…Introduction<p>It is generally accepted that during body position changes from horizontal to vertical there is a short-lasting shift of a certain CSF volume from the cranium into the hydrostatically lower parts of the spinal space, which leads to transitory CSF pressure decrease to negative values.…”

Merlin loss increases SC NPC growth, glial differentiation and cell survival. by Cynthia Garcia (562261)

“…<p><i>Nf2</i> loss results in a (<b>A</b>) 1.8-fold increase in neurosphere diameter (p<0.0001; two-tailed Mann-Whitney U-test), (<b>B</b>) 3.6-fold increase in cell number at day 8 (p<0.001; 2-way ANOVA), and (<b>C</b>) a 1.7-fold increase in clonogenic expansion relative to WT SC NPCs (p = 0.003; two-tailed; two-tailed Mann-Whitney U-test). …”

Table_1_Prevalence and WGS-based characteristics of MRSA isolates in hospitals in Shanghai, China.XLS by Hongzhi Zhang (425117)

“…<p>Methicillin-resistant Staphylococcus aureus (MRSA) isolates remain a serious threat to global health despite a decrease in MRSA infections since 2005. …”

Postsynaptic Syntaxin 4 negatively regulates the efficiency of neurotransmitter release by Kathryn P. Harris (5899229)

DataSheet_1_An integrative multi-omic analysis defines gut microbiota, mycobiota, and metabolic fingerprints in ulcerative colitis patients.docx by Matteo Scanu (13197234)

“…</p>Results<p>In the UC cohort, we reported the increase of Streptococcus, Bifidobacterium, Enterobacteriaceae, TM7-3, Granulicatella, Peptostreptococcus, Lactobacillus, Veillonella, Enterococcus, Peptoniphilus, Gemellaceae, and phenylethyl alcohol; and we also reported the decrease of Akkermansia; Ruminococcaceae; Ruminococcus; Gemmiger; Methanobrevibacter; Oscillospira; Coprococus; Christensenellaceae; Clavispora; Vishniacozyma; Quambalaria; hexadecane; cyclopentadecane; 5-hepten-2-ol, 6 methyl; 3-carene; caryophyllene; p-Cresol; 2-butenal; indole, 3-methyl-; 6-methyl-3,5-heptadiene-2-one; 5-octadecene; and 5-hepten-2-one, 6 methyl. …”

Relative difference in the peak value of the free energy barrier during R4 transition for all hydrophobic core residues mutated to alanine, compared to the value for WT. by Christine S. Schwaiger (302070)

“…<p>The standard error for the WT is the absolute standard error. A decrease or increase is defined by the cutoff 5 kJ/mol. …”

Kidneys grown in the low-volume glass system show less evidence of stress. by David D. R. Sebinger (364856)

“…<p>In (A) the samples labelled ‘short’ are of medium conditioned from day 0–2 and those labelled ‘long’ are from days 2–4. …”

Gradient-based Regularization Parameter Selection for Problems with Non-smooth Penalty Functions by Jean Feng (90943)

Filtration of Macrophage Migration Inhibitory Factor (MIF) in Patients with End Stage Renal Disease Undergoing Hemodialysis by Peter Luedike (816009)

“…MIF plasma levels were markedly decreased 2 hour after initiation of HD (MIF plasma level pre-HD 84.8±6 ng/ml to intra-HD 61.2±5 ng/ml p<0.001) and were replenished already 20 min after termination of HD to basal levels (intra-HD 61.2±5 ng/ml to post-HD 79.8±5 ng/ml, p<0.001).…”

Learning from failure and the evolution of achievability. by Federico Mancinelli (11084630)

“…For illustration purposes, we divided our subjects into two groups using a median split on I-scores. …”

Deletion at <em>ITPR1</em> Underlies Ataxia in Mice and Spinocerebellar Ataxia 15 in Humans by Joyce van de Leemput (271956)

“…Through linkage and sequence analysis we show here that this disorder is caused by a homozygous in-frame 18-bp deletion in <em>Itpr1</em> (<em>Itpr1^Δ18/Δ18</em>), encoding inositol 1,4,5-triphosphate receptor 1. …”

Data Sheet 1_Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators.pdf by Michael Hecker (51971)

“…Blood samples were collected immediately before and after therapy to isolate plasma or serum as well as immune cells. We then measured (1) concentrations of the immunoglobulin isotypes IgG, IgM and IgA, (2) antibody reactivities against 12 peptides derived from potential autoantigens and Epstein-Barr virus proteins, (3) frequencies of CD19⁺ B cells, CD3⁺ T cells and CD14⁺ monocytes, (4) transcriptome profiles of CD19⁺ B cells and CD4⁺ T cells and (5) mRNA levels of 7 cytotoxicity-related genes in CD4⁺ T cells. …”