Image_1_Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury.JPEG by Ryan P. Bruhns (13197621)

“…Introduction<p>Traumatic brain injury (TBI) is a leading cause of disability in the US. Angiotensin 1-7 (Ang-1-7), an endogenous peptide, acts at the G protein coupled MAS1 receptors (MASR) to inhibit inflammatory mediators and decrease reactive oxygen species within the CNS. …”

Data_Sheet_1_Systematic assessment of clinical and bacteriological markers for tuberculosis reveals discordance and inaccuracy of symptom-based diagnosis for treatment response mon... by Bariki Mtafya (349098)

“…A decrease in TB-MBLA positivity reflected a fall in bacillary load, 5.7 ± 1.3- at baseline to 0.30 ± 1.0- log₁₀ eCFU/ml at month 6, and closer to cough resolution than other bacteriological measures, accounting for the only one bacteriologically positive case out of seven still coughing at month 6. …”

Distribution of differences of DNA methylation between normal mammary glands and mammary carcinomas. by Masaru Takabatake (3202710)

“…The curve shows a simulated normal distribution (mean = 0, standard deviation = 2.5) with the same spread as the data, but centered on zero to indicate the null hypothesis of no global trend. …”

NPB304 affected P-gp function and increased paclitaxel accumulation in P-gp-overexpressing resistant cells and tumor tissue. by Mei Mei (610571)

“…The data represent the mean ± SD. *p<0.05, **p<0.01. (C) NPB304 treatment promoted bidirectional permeability but decreased the efflux ratio of paclitaxel in a Caco-2 monolayer model. …”

Passive listening and go/No-go tasks feature comparable electrophysiological responses. by Sarah H. McGill (22505225)

“…<p>The differences between the mean peristimulus spectrograms of maximum-intensity auditory stimulus trials (65.7 dB) and no-stimulus trials (63.5 dB white noise only) are shown here for passive listening (left) and go/no-go (right tasks). …”

Clinical and epidemiological profile of patients with hypertensive peak after Ahmed glaucoma valve implant by Flávia da Silva Vilas-Boas (5910116)

“…After 6 months of follow-up the mean IOP decreased (16.4 ± 6.74 mmHg), with 2.23 ± 1.45 medications. …”

Phytol Suppresses Established Arthritis by Malin Hultqvist (75086)

“…Lines represent mean values.</p> <p>(C) Phytol decreases arthritis severity in the chronic phase of arthritis. …”

Tracking progress towards malaria elimination in China: Individual-level estimates of transmission and its spatiotemporal variation using a diffusion network approach - Fig 4 by Isobel Routledge (5315369)

Synthesis, Crystal Structure, EPR and DFT Studies, and Redox Properties of [2]Tetramethyldisilacobaltocenophane by Holger Braunschweig (1370640)

“…As was shown by cyclic voltammetry in THF, <b>1</b> is quasi-reversibly oxidized to the neutral cobaltocenium cation [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁺ (<b>8</b>) at a potential of <i>E</i>°_1/2 = −1.27 V (vs the Fc/Fc⁺ couple) and quasi-reversibly reduced to the corresponding anion [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁻ (<b>9</b>) at <i>E</i>°_1/2 = −2.40 V. …”

Synthesis, Crystal Structure, EPR and DFT Studies, and Redox Properties of [2]Tetramethyldisilacobaltocenophane by Holger Braunschweig (1370640)

“…As was shown by cyclic voltammetry in THF, <b>1</b> is quasi-reversibly oxidized to the neutral cobaltocenium cation [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁺ (<b>8</b>) at a potential of <i>E</i>°_1/2 = −1.27 V (vs the Fc/Fc⁺ couple) and quasi-reversibly reduced to the corresponding anion [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁻ (<b>9</b>) at <i>E</i>°_1/2 = −2.40 V. …”

NMR analyses of the HPV16 E6/E6APpep and HPV16 E6/pep11** interactions. by Katia Zanier (17371)

“…Note that in the case of spectra of E6/pep11** samples some signals have lower intensity in the red spectrum than in the cyan spectrum (see enlarged view of lower panel). This decrease in signal intensity is concomitant with the appearance of a white precipitate of E6 in the NMR tube. …”

The effect of mutation rate variation. by Thomas Mailund (51584)

“…We split the alignment into segments geometrically distributed with mean length 500 bp and 2 kbp, and the mutation rate is then scaled by a random value chosen uniformly in the range 0.75 to 1.25 or 0.5 to 1.5. …”

Induced Wnt signaling post-SE coordinates AMPK and mTOR signaling pathways. by Roaya S. Alqurashi (11243136)

“…(n = 3–5 for each group). Data are represented as mean ± SEM. …”

Fig 3 - by Amanda L. Laverty (9248648)

“…Water temperature ranged from 2.1–9.5°C. Note the decreased range of the Y-axis relative to Fig 3A. …”

siRNA screening system to identify regulators of insulin promoter activity. by Gregory M. Ku (188067)

“…If the siRNA targets a positive regulator, GFP/mCherry MFI decreases. …”

DataSheet_1_Differences in Prostate Cancer Incidence and Mortality in Lower Saxony (Germany) and Groningen Province (Netherlands): Potential Impact of Prostate-Specific Antigen Tes... by Sanny Kappen (10889607)

“…Trends in age-standardized incidence rates (ASIR) and mortality rates (ASMR) for specific age groups were assessed using joinpoint regression.</p>Results<p>The mean annual PCa ASIR between 2003 and 2012 was on average 19.9% higher in Lower Saxony than in Groningen (120.5 vs. 100.5 per 100,000), while the mean annual ASMR was on average 24.3% lower in Lower Saxony than in Groningen (21.5 vs. 28.4 per 100,000). …”

Effects of therapeutic and aerobic exercise programs in temporomandibular disorder-associated headaches by Paula Manuela Mendes MOLEIRINHO-ALVES (12659778)

“…Methodology Thirty-six patients diagnosed with headache attributed to TMD participated in the study and were divided into three groups of 12 patients: a therapeutic exercise program (G1, mean age: 26.3±5.6 years), a therapeutic and aerobic exercise program (G2, mean age: 26.0±4.6 years), and an aerobic exercise program (G3, 25.8±2.94 years). …”

Spatial regulation of platelet spreading. by Ashley Kita (200234)

“…On stripes of protein thinner than 5–6 µm, only a fraction of a platelet's final spread area is on protein. …”

Inhibition of Wnt signaling blocks adenocarcinoma cell proliferation. by Marina Pasca di Magliano (81389)

“…Transfection with an <i>Icat–IRES-eGFP</i> expression vector (<i>Icat</i>, black) or dominant negative Lef – <i>IRES-eGFP</i> (<i>dnLef</i>, gray) strongly inhibits growth of four pancreatic cancer cells lines, measured as the ability to incorporate BrdU. …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”