A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population by Victoria L. Herrera (383897)

“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”

The AMPK inhibitor CC exacerbates palmitate-induced decreases in viability. by Dustin M. Lee (8207457)

Rapamycin treatment significantly decreases induction of lytic KSHV proteins. by Lisa A. Nichols (357612)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA_A-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”

Flies decrease the level of aggression as the availability of food resource increases. by Rod S. Lim (622045)

TQ decreases CXCR4 expression on MM cells and CXCL12-induced CXCR4/CD45 association. by Gamal Badr (113166)

Influence of the Lactotripeptides Isoleucine–Proline–Proline and Valine–Proline–Proline on Systolic Blood Pressure in Japanese Subjects: A Systematic Review and Meta-Analysis of Ra... by Aurelie Chanson-Rolle (758940)

“…The analysis showed that consumption of IPP/VPP induced a significant reduction in SBP as compared with placebo in Japanese subjects, with an estimated effect of -5.63 mm Hg (95% CI, -6.87 to -4.39, P<0.0001) and no evidence of publication bias. …”

HDAC5 inhibitors reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

Preincubation with papaverine leads to decreases in phosphorylation of the mypt1 in HSV. by Kyle M. Hocking (402156)

The saturated fatty acid palmitate decreases viability and induces apoptosis in HUVECs. by Dustin M. Lee (8207457)

Fig 5 - by Matthew C. Kochem (18476069)

Subjects:

NDRG2 is decreased during LX-2 activation. by Jiandong Yang (196004)

CCN3 protein decreases β-cell proliferation. by Renée Paradis (326111)

Intracameral injections of ATX inhibitor decreases IOP in rabbits. by Padma Iyer (141117)

“…Drug treated eyes showed a significant decrease in IOP from the baseline (by 6–7 mm Hg) at 24 and 48 hrs based on paired t-test. …”

Metformin inhibits glutaminase activity in a dose dependent manner: from 17.5% at 10 mM up to 68% at 100 mM (A) (* p<0.05). by M. Mar Díaz-Herrero (646639)

oAβ enhances lysosomal acidification in NG and HG mixed glia cultures. by Yung-Cheng Huang (3443450)

Subjects:

A New Rotane Family:  Synthesis, Structure, Conformation, and Dynamics of [3.4]-, [4.4]-, [5.4]-, and [6.4]Rotane¹ by Lutz Fitjer (2466634)

“…The structures of <b>6</b>, <b>7</b>, and <b>8</b> were determined by high-precision low-temperature X-ray analyses and by force field calculations using the search routine HUNTER in connection with MM3(92). The following special features were observed:  From <b>5</b> to <b>8</b>, the bond angles of the central ring increase while the bond angles at the spiro center of the spiroannelated cyclobutane rings decrease. …”

HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”

Preincubation with papaverine leads to decreases in phosphorylation of the myosin light chain in HSV. by Kyle M. Hocking (402156)

Salt stress responsiveness of a wild cotton species (<i>Gossypium klotzschianum</i>) based on transcriptomic analysis - Fig 5 by Yangyang Wei (436909)