FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia by Xiaofeng Wang (119575)

“…Furthermore, we found that FGFR3 interacted with ATG12–ATG5 conjugate by binding to ATG5. More intriguingly, FGFR3 signaling was found to decrease the protein level of ATG12–ATG5 conjugate. …”

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-5 by Hong Yang (37298)

Transient convection-diffusion of thrombin into and out of a fibrin domain exposed to venous flow. by Jason Chen (15937)

Subjects:

Lung cancer cell lines secrete BMP2 and knockdown of BMP2 decreases BMP signaling and induces cell death. by Elaine Langenfeld (402034)

“…(<b>D</b>) Western blot analysis of H1299 cells in SFM 48 hours after being transfected with control siRNA or siRNA targeting BMP2. BMP2 knockdown causes a decrease in expression of pSmad 1/5 and Id1. …”

Botulinum toxin A (3.5 U/kg) decreases mechanical allodynia induced by IoNC- injury in rats. by Boris Filipović (336089)

Decreased IL-1β levels observed in HPV16 E6-positive cells are independent of autophagy or lysosomal degradation. by Martina Niebler (440620)

Decreased HIF levels associated with hyperoxic cell state. by Julie M. Koeman (108185)

“…<p>(A) Normalized densitometry of HIF-1α protein levels (•),HIF-1β protein levels (▴), and HIF-1 DNA-binding activity (⧫) as presented in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000176#pgen-1000176-g005" target="_blank">Figure 5B</a> of the Jiang et al. article. …”

Inhibition of PI3K activity decreases uptake of Opa_CEA-expressing gonococci via CEACAM1. by Maike Voges (154488)

Dietary zinc repletion decreases Zip10 expression. by Louis A. Lichten (215913)

“…Values are given as means ± SD. Values with a different superscript are significantly different at <i>P</i><0.05 or greater, <i>n</i> = 5. …”

Inhibition of ER stress-induced autophagy aggravates, while activation of ER stress-induced autophagy decreases apoptosis in HCC cells. by Yan Lei (535846)

Decreasing the front-to-rear difference of myosin II activity induced the collapse of leading front and reversed soma translocation of Schwann cells. by Ying Wang (11406)

Decrease of Paneth cells and goblet cells in small intestine upon deletion of TNKSs. by Pan Ye (2902336)

IODVA1 inhibits lamellipodia and circular dorsal ruffle (CDR) formation in MDA-MB-231 cells and decreases Rac activation. by Anjelika Gasilina (8566296)

Decreased BK responsiveness of p38 activation is evident in both PS-1 and PS-2 FAD mutant AD fibroblasts. by Graziella Mendonsa (374346)

METH decreased basal pERK1/2 levels and potentiated ERK1/2 phosphorylation induced by 6-OHDA. by Amina El Ayadi (341955)

“…METH decreased activation of ERK 1/2 in a concentration-dependent manner (0, 0.5, and 1 mM at the 24 hr time point) and enhanced the activation of ERK1/2 after 6-OHDA exposure. …”

Exogenous IL-2 and IL-7 decrease suppression of Teff proliferation and cytokine production, but do not decrease apoptosis. by Yvonne Vercoulen (259275)

Combination treatment of LY294002 and tamoxifen rapidly decreased Akt and GSK-3β phosphorylation in C6 glioma cells. by Cuixian Li (341124)

Combination treatment with LY294002 and tamoxifen remarkably decreased AKT and GSK-3β phosphorylation in C6 glioma cells. by Cuixian Li (341124)

Intratumoral injection of rVP1 attenuates subcutaneous BNL tumor growth by inducing apoptosis and decreasing the level of CCL2. by Tai-An Chen (211390)

Silencing of SphK1, but not SphK2, decreases HPAEC migration by S1P in wound healing ECIS assay. by Evgeny V. Berdyshev (307465)