Downstream element mutations affect MHC class I promoter activity <i>in Vitro</i>. حسب Namhoon Lee (235410)

"…<p><b>A) Mutation of the downstream elements decreases MHC class I promoter activity </b><b><i>in vitro</i></b><b>. …"

Table 1_How happy is healthy enough? Uncovering the happiness threshold for global non-communicable disease prevention.pdf حسب Iulia Cristina Iuga (22465555)

"…A Panel Smooth Transition Regression (PSTR) model examined the effect of national Life-Ladder scores on the 30-to-70-year NCD mortality rate, controlling for alcohol consumption, obesity prevalence, urbanization, PM2.5 exposure, health expenditure, GDP per capita and governance quality. …"

Schematic representation of c-Myc regulating cell proliferation and controlling cell fate in BASCs through both transcriptional and post-transcriptional pathways. حسب Jie Dong (12143)

"…The model (from our work and others) depicts c-Myc regulating downstream gene expression through two distinct mechanisms. 1) Transcriptional level: c-Myc directly regulates mRNA transcription with its partner Max through c-Myc/Max binding sites in the 5′-flanking promoter region of target genes. 88 genes were identified as potential downstream genes through a position weight matrix based method in conjunction with changes in mRNA level. 2) Post-transcriptional level: c-Myc indirectly regulates mRNA and protein expression through miRNAs. …"

Weak magnetic fields disturb cytoskeleton reassembly after nocodazole exposure, and influence actin polymerization. حسب Abasalt Bahrami (21989867)

"…The median alignment level for the nocodazole-disrupted cells under the ambient field (14.5) is 1.6 that of the nocodazole-disrupted cells under the applied magnetic field (8.7), with a p = 0.0278 0.05 indicated with a star. …"

Image_1_Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model scat.JPEG حسب Emily S. Hartman (5339009)

"…Surprisingly, apoptosis is significantly decreased in the scat bone marrow at the proerythroblastic (15.3%; p = 0.004), polychromatophilic (8.5%; p = 0.01), and orthochromatic (4.2%; p = 0.02) stages. …"

Evolution of diabetes in Brazil: prevalence data from the 2013 and 2019 Brazilian National Health Survey حسب Rodrigo Citton Padilha dos Reis (12740955)

"…Drivers of this rise include increase in size (9.9%) and aging (1.8%) of the Brazilian population, and to all other factors, including increased case-detection and incidence, as well as decreased diabetes mortality (24.7%). Main correlates of greater prevalence - adjusted by the Poisson regression with robust variance - were older age (PR = 27.2, 95%CI: 1.2-42.9 for ≥ 65 years vs. 18-24 years), hypertension (PR = 2.6, 95%CI: 2.4-2.8 vs. normotension), and obesity (PR = 2.3, 95%CI: 2.1-2.5 vs. …"

Influence of the Contact Area on the Current Density across Molecular Tunneling Junctions Measured with EGaIn Top-Electrodes حسب Philipp Rothemund (1419079)

"…Measurements of current density, <i>J</i>(<i>V</i>), across SAMs of decanethiolate on silver demonstrate that <i>J</i>(<i>V</i>) increases with <i>A</i>_g when the contact area is small (<i>A</i>_g < 1000 μm²), but reaches a plateau between 1000 and 4000 μm², where <i>J</i>(0.5 V) ≈ 10^{–0.52±0.10} A/cm². …"

Figure S1 - The Association of Cysteine with Obesity, Inflammatory Cytokines and Insulin Resistance in Hispanic Children and Adolescents حسب Amany K. Elshorbagy (137193)

"…Common to all 5 knockouts is decreased plasma cyste(i)ne <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Kendig1" target="_blank">[3]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Lieberman1" target="_blank">[46]</a> or tCys <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Gupta1" target="_blank">[1]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Teng2" target="_blank">[6]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Mani1" target="_blank">[45]</a>. …"

HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy حسب Alexander Lind (5221088)

"…Among subjects with the <i>HLA</i>-<i>DRB5*01</i>:<i>01</i>:<i>01-DRB1*15</i>:<i>01</i>:<i>01-DQA1*01</i>:<i>02-DQB1*06</i>:<i>02</i> haplotype, a second <i>DRB4*01</i>:<i>03</i>:<i>01-DRB1*04</i>:<i>01</i>:<i>01-DQA1*03</i>:<i>02//*03</i>:<i>03</i>:<i>01-DQB1*03</i>:<i>01</i>:<i>01</i> haplotype (<i>p</i> = 2.02E^-2), but not homozygosity for <i>DRB1*15</i>:<i>01</i>:<i>01-DQB1*06</i>:<i>02</i>:<i>01</i> (<i>p</i> = 7.49E^-1) conferred association to NT1. …"

Results from the first culturally tailored, multidisciplinary diabetes education in Lebanese adults with type 2 diabetes: effects on self-care and metabolic outcomes حسب Sukkarieh-Haraty, Ola

"…This pilot-study tested the effect of culturally-tailored education targeting diabetes selfcare on glycemia and cardiovascular risk factors of Lebanese with type 2 diabetes mellitus (T2DM) (n = 27; Age: 61 ± 10 yrs, 59% males, HbA1c: 8.98 ± 1.38%). Results: Diabetes self-care (Diet, Self-Monitoring Blood Glucose and foot care) improved after 6 months, which was reflected in a significant drop in glycemic levels (HbA1c:-0.5%; FPG: − 38 mg/dl), and cholesterol/HDL ratio (4.45 ± 1.39 vs. 4.06 ± 1.29). …"
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Change of signaling molecules, proliferation, apoptosis, invasion ability and MMP-2 expression in 786-0 cells with knockdown EpoR. حسب Pengjie Wu (307334)

"…In 786-0 cells expressing EpoR siRNA, EpoR and p-EpoR decreased by >90%, p-STAT5 decreased by >60%, but p-Erk1/2 increased by >36%, as compared with those in the two controls. …"

Developmental changes in percentage of EEG total power within the delta and theta frequency ranges during vigilance states of the neonatal mouse. حسب Nicholas Rensing (3686332)

"…<p>(<b>A</b>) During wakefulness, percentage of delta (1-4Hz) in EEG decreases until P17 and percent theta (4–8.5Hz) increases starting at P14. p<0.001, compared to ***P21; ### P17; ◆◆◆ P14; p<0.01 compared to ## P17; p<0.05 compared to ^{<b><i>&</i></b>}P12 by one-way repeated measures ANOVA with Tukey; n = 8–9 mice per group. …"

DataSheet_1_2-Deoxy-D-glucose Alleviates Collagen-Induced Arthritis of Rats and Is Accompanied by Metabolic Regulation of the Spleen and Liver.zip حسب Hongxing Wang (3165948)

"…The changes in the gene-metabolite network of bile secretion in the spleen correlated with a decreased plasma L-acetylcarnitine level in CIA rats and an increase following 2-DG treatment. …"

Data_Sheet_1_Spatiotemporal Dynamics of the Carbon Budget and the Response to Grazing in Qinghai Grasslands.docx حسب Xiaotao Huang (9019376)

"…The NEE of Qinghai grasslands fluctuated from 1979 to 2018, with an average value of −5.16 gC/m². After 2,000, GPP increased, and NEE decreased in a fluctuating manner. …"

Doxycycline-induced expression of MTG16 in Raji/MTG16 Tet-On 3G cells. حسب Parveen Kumar (428921)

"…Data are represented as means±SEM for (A) n = 3, (D) n = 3 and (E) n = 3 and were compared by the two-way ANOVA followed by Bonferroni (D) or the Tukey's multiple comparison post-hoc tests (E) (*p<0.05; ***p<0.001). …"

Charge and Exciton Transfer Simulations Using Machine-Learned Hamiltonians حسب Mila Krämer (8991095)

"…Quantum-mechanical simulations of charge and exciton transfer in molecular organic materials are a key method to increase our understanding of organic semiconductors. …"

Charge and Exciton Transfer Simulations Using Machine-Learned Hamiltonians حسب Mila Krämer (8991095)

"…Quantum-mechanical simulations of charge and exciton transfer in molecular organic materials are a key method to increase our understanding of organic semiconductors. …"

Effect of baicalein on the mobility and invasive potency of human gallbladder carcinoma GBC-SD and SGC996 cells. حسب Tian-Yu Liu (686078)

"…<p>Cells were treated with 7.5, 15, 30 and 60μmol/L baicalein for 12 h prior to the migration (A) or invasion (B) assay.…"

Climatological ranges and average annual anomalies for U.S. Pacific coral reef ecosystems. حسب Jamison M. Gove (404321)

"…Islands and atoll names are presented as a three-letter code (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061974#pone-0061974-t001" target="_blank">Table 1</a> for full location names), grouped and color-coded by region (see Fig. 1 for map of locations), and oriented by decreasing latitude from left to right (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061974#pone-0061974-t001" target="_blank">Table 1</a> for specific positions). …"

Data_Sheet_1_On-farm antimicrobial usage in commercial turkey production in the United States, 2013–2021.PDF حسب Randall S. Singer (8097428)

"…The estimated percentage of turkey poults placed that received hatchery antimicrobials decreased from 96.9% in 2013 to 40.5% in 2021. The use of in-feed antimicrobials was practically eliminated, with in-feed tetracycline being the only medically important antimicrobial used in 2021. …"