LRG1 modifies the effects of TGFβ on myeloid and hematopoietic progenitor cell growth. by Lawrence J. Druhan (376410)

“…A dose-response reduction in cell proliferation as measured by the decreasing A490-A650 is observed with increasing concentrations of TGFβ that is mitigated by the addition of LRG1. …”

Table 9_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Table_1_Direct and Indirect Climate Change Impacts on Brown Trout in Central Europe: How Thermal Regimes Reinforce Physiological Stress and Support the Emergence of Diseases.pdf by Florian Borgwardt (8895812)

“…In respect of PKD, the amount of river reaches having unlikely outbreaks of PKD decreased from 72.6% under current conditions to 37.7% in the far future RCP8.5 scenario. …”

GNB1 and SCARB2 involvement in lipid metabolism of human subcutaneous adipocytes. by Takuya Kitamoto (11721639)

“…Abbreviations: ADIPOQ, adiponectin, C1Q and collagen domain containing; α, alpha subunit of the G proteins; β, GNB1; C1P, ceramide-1-phosphate; Cer, ceramide; CERK, ceramide kinase; CDH13/T-cadherin, cadherin 13; CEPT, choline/ethanolaminephosphotransferase; ChE, cholesterol ester; Chol, cholesterol; DG, diacylglycerol; DGAT, diacylglycerol O-acyltransferase; ER, endoplasmic reticulum; G3P, glycero-3-phosphate; GPCR, G protein-coupled receptor; γ, gamma subunit of the G proteins; HSPA8/HSC70, heat shock protein family A; IP₃, inositol (1,4,5)-trisphosphate; LAMP1/2, lysosomal associated membrane protein 1/2; LPA, lysophosphatidic acid; NPC1/2, NPC intracellular cholesterol transporter 1/2; PA, phosphatidic acid; PC, phosphatidylcholine; PI, phosphatidylinositol; PLIN2, perilipin 2; PLPP1, phospholipid phosphatase 1; PLC, phospholipase C; PNPLA2/ATGL, patatin like phospholipase domain containing 2; SCARB2, scavenger receptor class B member 2; SGMS/SMS, sphingomyelin synthase; SM, sphingomyelin; SOAT, sterol O-acyltransferase; SPH, sphingosine; SQSTM1/p62, sequestosome 1; TG, triacylglycerol; TMT1A/METTL7A, methyltransferase-like protein 7A.…”

Table_1_The association between thyroid-stimulating hormone and thyroid nodules, goiter and thyroid antibody positivity.docx by Shaohan Li (10942453)

“…Low TSH levels (0.27–1.41 IU/mL) were identified as a risk factor for TN (odds ratio [OR], 1.46; 95% CI: 1.14-1.87) and GR (OR 5.90, 95% CI 2.27-15.3). …”

Image_1_Comparative efficiency of silica gel, biochar, and plant growth promoting bacteria on Cr and Pb availability to Solanum melongena L. in contaminated soil irrigated with was... by Umm e Rabiya (13197495)

“…<p>Crop irrigation with untreated wastewater is a routine practice in developing countries that causes multiple human health consequences. …”

Table 7_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Table 3_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Image 1_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.jpeg by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Data Sheet 1_Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Nelumbo).zip by Jiaxin He (11256475)

“…</p>Results<p>It revealed that the broad petal variation of M512 was caused by a reduction in petal length while maintaining width, whereas the narrow petal phenotype of CSFY resulted from a combination of increased length and decreased width. …”

image_3_Impaired Differentiation of Langerhans Cells in the Murine Oral Epithelium Adjacent to Titanium Dental Implants.jpeg by Oded Heyman (5139533)

“…Further analysis revealed that while the expression of the TGF-β1 canonical receptor activing-like kinase (ALK)5 was upregulated, expression of its non-canonical receptor ALK3 was decreased. …”

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Image2_Expression pattern of the fused in sarcoma gene and its contextual influence on the density-specific response of the growth hormone/insulin-like growth factor 1 axis in zig-... by Lingzhan Xue (11117426)

“…The expression of fus exhibited a remarkable positive correlation with a specific growth rate. …”

Image_1_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

The putatively encoded protein isoform smLRP1 is expressed in human tumour cell lines. by Marlen Kolb (759117)

“…GADPH expression served as control. (<b>A</b>) In the absence of secondary anti-mouse antibody (1:5,000), no smLRP1 protein band (32 kDa) could be detected in A459. …”

Image_3_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Image 2_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.tif by Xiaofeng Li (342614)

“…Background<p>Ovarian cancer remains the deadliest gynecological malignancy with 5-year survival rates below 40% due to frequent recurrence and chemoresistance. …”

Manipulation of Lrrk enhances tau neurotoxicity. by Farah H. Bardai (6107924)

“…<p>(A) Increasing or decreasing <i>Drosophila</i> Lrrk enhances the toxicity of human tau^R406W, which is further enhanced by expressing mutant forms of Lrrk engineered to mimic Parkinson’s disease mutations. …”

Table_2_An etude for post-pandemic practice: The impact of the COVID-19 pandemic on practice methods and instrumental technique.DOCX by Ellen Fallowfield (14287268)

“…Participants were statistically more likely to report “never” watching online tutorials than “often” (p = 0.014), but, of those that did watch such material, 75% agreed that it had a positive impact upon their practice. Most participants created digital content during this period; only 5% produced no such material. …”

Supplementary materials: Cost–effectiveness of sotagliflozin for the treatment of patients with diabetes and recent worsening heart failure by Jaehong Kim (261471)

“…<b>Results:</b> Sotagliflozin use decreased annualized rehospitalization rates by 34.5% (0.228 vs 0.348, difference: -0.120), annualized emergency department visits by 40.0% (0.091 vs 0.153, difference: -0.061) and annualized mortality by 18.0% (0.298 vs 0.363, difference: -0.065) relative to standard of care, resulting in a net gain in QAYs of 0.425 for sotagliflozin versus standard of care. …”