Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner by Khondoker Alam (1443499)

“…Pretreatment with bortezomib (50–250 nM, 2–7 h) significantly decreased transport of [³H]CCK-8, a specific OATP1B3 substrate, in HEK293-OATP1B3 and human sandwich-cultured hepatocytes (SCH). …”

PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine. by Shaily Malik (226661)

“…<p>(A) Human neurons were treated with 100 ng/ml Tat and/or 100 nM morphine for 12 hours with or without pre-treatment with 40 ng/ml PDGF-BB. …”

Image_1_Dysbiosis of gut microbiota and decreased propionic acid associated with metabolic abnormality in Cushing’s syndrome.jpeg by Qin Zhang (58638)

“…</p>Methods<p>A total of 23 patients with Cushing’s syndrome (18 female and 5 men, aged 47.24 ± 12.99 years) and 30 age-, sex-and BMI-matched healthy controls (18 female and 12 men, aged 45.03 ± 6.69 years) were consecutively recruited. …”

Chronic Arachidonic Acid Administration Decreases Docosahexaenoic Acid- and Eicosapentaenoic Acid-Derived Metabolites in Kidneys of Aged Rats by Masanori Katakura (816112)

“…Levels of docosahexaenoic acid-derived protectin D1, eicosapentaenoic acid-derived 5-, and 18-hydroxyeicosapentaenoic acids, and resolvin E2 and E3 decreased in the ARA-administered group. …”

V5-SgG2 transfection in the epidermis modifies the termination site of peptidergic FNE. by Jorge Rubén Cabrera (685511)

Image_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Table_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.docx by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Image_3_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Image_2_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Decreasing ShcA expression enhances TGF-β-induced Smad signaling. by Baby Periyanayaki Muthusamy (838234)

“…Note the enhanced basal pSmad3 or pSmad2 levels in cells transfected with ShcA siRNA. ShcA immunoblotting reveals decreased ShcA levels in cells transfected with ShcA siRNA, and GAPDH immunoblotting serves as loading control. …”

Variable importance plot (mean decrease accuracy and mean decrease Gini). by Fernando Martinez-Taboada (8655132)

Retinoic acid decreases ATF-2 phosphorylation and sensitizes melanoma cells to taxol-mediated growth inhibition-2 by Ying Huang (53474)

“…</p><p>Published online 12 Feb 2008</p><p>PMCID:PMC2265711.</p><p></p>…”

Ligand-Controlled Magnetic Interactions in Mn₄ Clusters by Erik Kampert (2330428)

“…Experimentally measured magnetic moments in high magnetic fields show that, upon electron density withdrawal, the main antiferromagnetic exchange constant <i>J</i>₁ decreases from −2.2 K for the [Mn₄(OAc)₄] cluster to −1.9 K for the [Mn₄(H₅C₆COO)₄] cluster and −0.6 K for the [Mn₄(F₃CCOO)₄] cluster, while <i>J</i>₂ decreases from −1.1 K to nearly 0 K and <i>J</i>₃ changes to a small ferromagnetic coupling. …”

Ligand-Controlled Magnetic Interactions in Mn₄ Clusters by Erik Kampert (2330428)

“…Experimentally measured magnetic moments in high magnetic fields show that, upon electron density withdrawal, the main antiferromagnetic exchange constant <i>J</i>₁ decreases from −2.2 K for the [Mn₄(OAc)₄] cluster to −1.9 K for the [Mn₄(H₅C₆COO)₄] cluster and −0.6 K for the [Mn₄(F₃CCOO)₄] cluster, while <i>J</i>₂ decreases from −1.1 K to nearly 0 K and <i>J</i>₃ changes to a small ferromagnetic coupling. …”

High concentrations of UA lead to decrease of TRACP 5b levels. by Zhi-Qi Wu (847506)

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand by David Hauton (341981)

“…Hearts of male offspring subjected to Maternal Hypoxia showed a 20% decrease in cardiac output (<i>P</i><0.05), despite recording a 2-fold increase in glucose oxidation (<i>P</i><0.01) and 2.5-fold increase (<i>P</i><0.01) in palmitate oxidation. …”

Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity by Kaytee L. Pokrzywinski (3605435)

Blocking CD88 decreased ANCA antigen translocation, ANCA-induced respiratory burst and degranulation in C5a-primed neutrophils. by Jian Hao (160736)

“…C and D: blocking CD88 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. …”

CDK5 knockdown increases TP53 and p27^Kip1 protein half-lives, increases nuclear localization of the two proteins, decreases p27^Kip1 p-T187 phosphorylation and induces p21^Cip1 in a TP53-dependent manner. by Shu Zhang (22238)

“…<p>(<b>A</b>) Transfection with CDK5 siRNA increased the half-life of p53 and p27^Kip1 protein. …”

Klf5 activates the transcription of the eIF5a gene through direct binding to its promoter. by Dong Ma (584680)

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