PPP2R5C HepKD in <i>db/db</i> mouse liver improves insulin sensitivity, decreases hyperglycemia, but worsens the dyslipidemia. by Yong-Sheng Cheng (803758)

“…<p><b>(A)</b> Hyperglycemia in <i>db/db</i> mice is decreased upon hypatocyte-specific PPP2R5C knockdown with adeno-associated virus. …”

AUC statistics as calculated from simulated time series. Each statistical metric was calculated within sliding windows, throughout the pre-critical interval. We considered five-, fifteen-, and thirty-day sliding windows. Given that the temperature of the system increased to 12°C on day sixty, we also considered three pre-critical intervals: Days 1 to 60, Days 20 to 60, and Days 30 to 60. To evaluate trends in these metrics, we calculated Kendall’s rank correlation coefficient during the pre-critical interval, and compared control (constant temperature, non-epidemic) and warming (warming treatment, epidemic emergence) coefficients across simulations and experimental populations by calculating the area under the curve (AUC) statistic. Values less than 0.5 suggest that a decrease in the statistical metric indicates emergence, while values greater than 0.5 suggest that an increase in the statistical metric indicates emergence, with more extreme values indicating stronger tre by Madeline Jarvis-Cross (22394247)

“…Values less than 0.5 suggest that a decrease in the statistical metric indicates emergence, while values greater than 0.5 suggest that an increase in the statistical metric indicates emergence, with more extreme values indicating stronger tre</p>…”

Reduction of Acc1 protein level decreases glucose-deprived stress granule formation. by Meaghen Rollins (3776008)

Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx by Rachel A. Cederberg (12827564)

“…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …”

Stimulation of Caco-2 cells with IFN-γ decreases claudin-4 expression. by Manigandan Lejeune (458492)

V2 vasopressin receptor abundance. by Sophie Constantin Lütken (689916)

Subjects:

Liquid–Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media by Qingwen Bai (5221280)

“…Our study provides a further step toward a deeper understanding of the kinetics of MLOs in crowded living cells.…”

Liquid–Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media by Qingwen Bai (5221280)

“…Our study provides a further step toward a deeper understanding of the kinetics of MLOs in crowded living cells.…”

Liquid–Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media by Qingwen Bai (5221280)

“…Our study provides a further step toward a deeper understanding of the kinetics of MLOs in crowded living cells.…”

JHMV N1347A has decreased replication in the olfactory bulbs of mice. by Catherine M. Kerr (21492574)

Change in log10 concentration (CFU/mL) from pre-UV disinfection (N0), immediately after UV disinfection (Nt), and after 24 hour repair incubations for dark (diamond, solid lines) a... by Daniel Ma (12698752)

C1INH significantly decreased renal C5a cleavage and limited C3b deposition in kidneys subjected to IRI. by Juan S. Danobeitia (4386205)

Dual-targeting approaches show agonistic effects in cell survival decrease due to either apoptotic cell death enhancement or cooperative PI3K-Akt-mTOR pathway downregulation. by Elke Tatjana Aristizabal Prada (833927)

rVλ6Wil fibrils cause oxidative stress in cardiomyocytes without a decrease in cellular ATP. by Helen P. McWilliams-Koeppen (116503)

“…<p>(A) After a 2 h incubation with rVλ6Wil fibrils or monomer, cellular ATP levels, as detected by luminescence (black bars), were not significantly reduced relative to the PBS-treated control. …”

Declining trend in the initial SARS-CoV-2 VL in hospitalized patients coinciding with a decrease in mortality rates. by Said El Zein (11442413)

Depletion of EphA3 or EphA4 recovers the decreased ERK and Akt activation and lytic gene expression in RNF5 KO PEL cells. by Xiaojuan Li (351842)

Time series of macrofaunal crustacean abundance at stations in DBO regions 2–5 over the 2010–2019 period. by Sue E. Moore (2932644)

5-HT supplementation induces mitochondrial damage. by Li Gao (131516)

Botulinum toxin A (3.5 U/kg) decreases mechanical allodynia induced by IoNC- injury in rats. by Boris Filipović (336089)

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-5 by Hong Yang (37298)