Image_3_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.jpeg by Xilong Kang (2548195)

“…The overexpression of miR-5112 decreased inflammatory cytokine production, accompanied by a reduction of IKKγ in flagellin-stimulated BMDCs. …”

Image_4_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.TIF by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”

Image_2_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.TIF by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”

Table_2_The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts.DOC by Hui Gao (169623)

“…Whole-transcriptome analyses identified a total of 235 transcripts that were differentially expressed in all six time points, most of which were inflammation-related genes. …”

DataSheet6_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Proteomic Insight into Functional Changes of Proteorhodopsin-Containing Bacterial Species <i>Psychroflexus torquis</i> under Different Illumination and Salinity Levels by Shi Feng (1662253)

Fecal Microbial Composition of Ulcerative Colitis and Crohn’s Disease Patients in Remission and Subsequent Exacerbation by Edgar S. Wills (532537)

“…Thiopurine use was found to be a significant cause of clustering as shown by Principal Coordinate Analysis and was associated with decreases in bacterial richness (Choa1 501.2 vs. 847.6 in non-users; p<0.001) and diversity (Shannon index: 5.13 vs. 6.78, respectively; p<0.01).…”

Data Sheet 1_Reduced pulmonary arterial compliance predicts poor short-term outcome in children with pulmonary arterial hypertension independent of pulmonary vascular resistance.pd... by Eva Gouwy (21408626)

“…Background and study aim<p>Pulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease with pulmonary vascular remodelling leading to an increased pulmonary vascular resistance (PVRi) and decreased pulmonary arterial compliance (PACi). …”

DataSheet4_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

complete data FOTS6639.xlsx by Andreas Nord (4533943)

“…This was likely driven by triggering of cerebral thermosensors in response to cooling of the poorly insulated head, the skin of which was 5.4oC colder at -30oC than at 0oC. Thermal conductance in winter was higher in yearling birds, probably because they were time/resource constrained from acquiring a high-quality plumage and sufficient fat reserves due to concomitant body growth. …”

Image_4_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.JPEG by Margaret Caroline Stapleton (17437713)

“…<p>Late-onset Alzheimer’s disease (LOAD) is a major health concern for senior citizens, characterized by memory loss, confusion, and impaired cognitive abilities. …”

Table_1_Acquisition of complement fixing antibodies targeting Plasmodium falciparum merozoites in infants and their mothers in Uganda.docx by Susanne E. Mortazavi (12863876)

“…</p>Results<p>We measured complement-fixing antibodies in newborns and their mothers in a malaria endemic area over 5 years follow-up and found that infants’ complement-fixing antibody levels were highest at birth, decreased until six months, then increased progressively until they were similar to birth at five years. …”

PowerPoint Slides for: Clinical Trial of Vadadustat in Patients with Anemia Secondary to Stage 3 or 4 Chronic Kidney Disease by Martin E.R. (3859435)

“…<b><i>Methods:</i></b> A phase 2a, multicenter, randomized, double-blind, placebo-controlled, dose-ranging trial (NCT01381094) was undertaken in adults with anemia secondary to CKD stage 3 or 4. …”

DataSheet1_Comparative Toxicity Assessment of Kratom Decoction, Mitragynine and Speciociliatine Versus Morphine on Zebrafish (Danio rerio) Embryos.docx by Thenmoly Damodaran (11304312)

“…</p><p>Results: Kratom decoction at a concentration range of ≥500 μg/ml caused 100% mortality of zebrafish embryos and decreased the hatching rate in a concentration-dependent manner. …”

Table_2_Gut microbiome variation in pulmonary TB patients with diabetes or HIV comorbidities.docx by Portia Abena Morgan (11883253)

“…</p>Results<p>Compared to the healthy controls, the gut microbiome of all the TB cohorts was characterized by a significant decreased alpha diversity and significant compositional changes. …”

Table_1_Genome-wide association study of coleoptile length with Shanxi wheat.XLSX by Naicui Wei (12000617)

“…In total, nine stable genetic loci were identified via 3VmrMLM under the three conditions, explaining 2.94–7.79% of phenotypic variation. Five loci on chromosome 2B, 3A, 3B, and 5B have not been reported previously. …”

Table_3_Structure and Function of Oral Microbial Community in Periodontitis Based on Integrated Data.xlsx by Zhengwen Cai (10986837)

“…Objective<p>Microorganisms play a key role in the initiation and progression of periodontal disease. …”

Data_Sheet_1_Gut Microbiota Modulates Intestinal Pathological Injury in Schistosoma japonicum-Infected Mice.docx by Beibei Zhang (509356)

“…Depletion of the gut microbiota by antibiotics, or transfer of the gut microbiota from normal to infected mice decreased the levels of IL-4, IL-5, and IL-13 and promoted the production of cytokines and mRNA levels of IL-10 and TGF-β in infected mice. …”

Supplementary Material for: The impact of parental myopia and high myopia on the hyperopia reserve of preschool children by Pu J. (3235923)

“…Parents were asked to complete a questionnaire about refractive status (no myopia, mild myopia <-3D, moderate myopia ≥-3D and ≤-6, and high myopia >-6D). …”

DataSheet_2_Gut microbiome variation in pulmonary TB patients with diabetes or HIV comorbidities.pdf by Portia Abena Morgan (11883253)

“…</p>Results<p>Compared to the healthy controls, the gut microbiome of all the TB cohorts was characterized by a significant decreased alpha diversity and significant compositional changes. …”