3,3′-Diindolylmethane Induces G₁ Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells by Lyndsey E. Shorey (171162)

“…Taken together, our results demonstrate a potential for therapeutic application of DIM in T-ALL.…”

DataSheet_1_Transcriptional changes in the gilthead seabream (Sparus aurata) skin in response to ultraviolet B radiation exposure.docx by Ricardo N. Alves (8839895)

“…S. aurata juveniles were exposed for 43 days to two experimental groups: 1) UVB (daily dose, 6 kJ m^-2; representing levels between 5 and 7 m depth); 2) Unirradiated treatment, used as a control. …”

Table_1_The changes and its significance of peripheral blood NK cells in patients with tuberculous meningitis.DOCX by Jie Mi (152887)

“…The proportion of TBM patients (48.7%) with a lower absolute count of NK cells than the normal reference value was significantly higher than that in NC (5.2%) and LTBI groups (4.0%) (p < 0.05), and slightly higher than that in NSTB group (36.0%) (p > 0.05). …”

Image_1_Microwave ablation with hydrodissection used for the treatment of vascular malformations: effectiveness and safety study.jpeg by Lu Wang (45927)

“…</p>Results<p>Among the 39 VMs, the maximum volume is 128.58ml, while the minimum volume is 0.99ml. After a mean follow-up of 13.06 ± 4.83 months, the mean numerical rating scale (NRS) score decreased from 5.13 ± 1.65 to 0.53 ± 0.83 (P<0.0001). …”

Data_Sheet_1_Tle4z1 Facilitate the Male Sexual Differentiation of Chicken Embryos.doc by Chen Chen (6544)

“…Background<p>Sex differentiation is a complex and precisely regulated process by multiple genes in chicken. …”

Tropical fishes can benefit more from novel than familiar species interactions at their cold-range edges by Angus Mitchell (8391018)

“…</p><p dir="ltr">3. All five tropical fish species showed increased anti-predator behaviours and decreased bite rate at their novel temperate range compared to their native tropical and subtropical ranges. …”

DataSheet_1_Immunoregulatory effects of RGMb in gut inflammation.docx by Magdiel Pérez-Cruz (6422627)

“…Anti-RGMb mAb (9D1) treatment decreased IFN-γ and significantly increased IL-5 and IL-10 in the gut of the treated mice compared to the isotype control treated mice.…”

Downregulation of Protein Kinase CK2 Activity Facilitates Tumor Necrosis Factor-α-Mediated Chondrocyte Death through Apoptosis and Autophagy by Sung Won Lee (222509)

“…It should be clarified in the future if autophagy observed is a consequence versus a cause of the degeneration <em>in vivo.…”

Image_1_Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart.jpeg by Yamin Rao (13166352)

“…In our cohort, invasive pEMPD presented increased expression of androgen receptor and decreased MUC5CA expression, and these two changes might bring to the shift of invasive phenotype. …”

DataSheet1_Albuca Bracteata Polysaccharides Attenuate AOM/DSS Induced Colon Tumorigenesis via Regulating Oxidative Stress, Inflammation and Gut Microbiota in Mice.docx by Ziyan Qin (4058464)

“…In this study, we investigate the properties of polysaccharides of A. bracteate, named ABP. The average molecular weight of ABP was 18.3 kDa and ABP consisted of glucose, mannose, galactose, xylose, galacturonic acid, glucuronic acid at a molar ratio of 37.8:8:2.5:1.7:1:1. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…The median OS was not reached (95% CI: 13.27-NR), with a 1-year OS rate of 73.5% (95% CI: 60.4–89.3%). …”

Table_4_Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.xlsx by Wan-Chun Li (450324)

“…Loss of HK2 in HNSCC cells resulted in reduced cell (in vitro) and tumor (in vivo) growth, as well as decreased epithelial-mesenchymal transition–mediated cell movement; in contrast, HK2-deficient HNSCC cells exhibited greater sensitivity to chemotherapeutic drugs cisplatin and 5-fluorouracil but are more resistant to photodynamic therapy, indicating that HK2 expression could selectively define treatment sensitivity in HNSCC cells. …”

Table2_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4 by Yu Tina Zhao (3359159)

“…Western blotting was employed to determine active-caspase 3, annexin V, and HDAC4 expression. As compared to wild type H9c2 group, HDAC4 overexpression remarkably led to a great increase in cell death as evident by the increased lactate dehydrogenase (LDH) leakage, ratio of caspase-3-positive cells as well as the upregulated levels of active-caspase 3 and annexin V shown by western blot analysis. …”

Differential Effects of Short-Term Treatment with Two AT₁ Receptor Blockers on Diameter of Pial Arterioles in SHR by Sébastien Foulquier (138858)

“…In the first study, 4-month-old male SHR were treated with telmisartan (TELMI, 2 mg/kg per day) or candesartan cilexetil (CANDE, 10 mg/kg per day) and compared to vehicle treated SHR and normotensive WKY. In a second study, SHR were treated with CANDE, pioglitazone (a PPAR-gamma agonist, PIO 2.5 mg/kg per day) or CANDE+PIO, compared to TELMI. …”

DataSheet_1_Magnetic Resonance Imaging Correlates of Immune Microenvironment in Glioblastoma.pdf by Alessandro Salvalaggio (8780132)

“…MRI features may represent a novel tool for investigating the microenvironment of GBM.…”

Muscle oxygenation in vastus lateralis and gastrocnemius during incremental running exercise: effect of exercise intensity, VO2max, sex and age by Hugo Kerhervé (618369)

“…The aim of this study was to describe the effect of exercise intensity, maximum oxygen utilisation (V ̇O_2MAX), sex and age on vastus lateralis (VL) and gastrocnemius (Gn) muscle oxygenation measured using near-infrared spectroscopy (NIRS) during incremental running exercise to exhaustion, in a participant group having a large range of V ̇O_2MAX.…”

Data_Sheet_1_Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris.doc by Chaonan Sun (4681345)

“…Passing flatus and constipation were significantly correlated with psoriasis (p < 0.05 in both cases). (2) The abundance of Ruminococcaceae family, Coprococcus_1 genus, and Blautia genus were decreased with psoriasis improvement (p < 0.05, respectively), which had been demonstrated significantly increased in psoriasis. (3) Mice receiving psoriatic microbes transplantation showed delayed recovery of psoriasiform dermatitis and less reduction of interleukin (IL)-17A than those receiving healthy microbiota or blank control (p < 0.05 and p < 0.01, respectively).…”

Data_Sheet_1_An Integrated Omics Approach Uncovers the Novel Effector Ecp20-2 Required for Full Virulence of Cladosporium fulvum on Tomato.docx by Mansoor Karimi-Jashni (12997986)

“…The Ecp20-2 gene encodes a small secreted protein of 149 amino acids with a predicted signal peptide of 17 amino acids. …”

Data_Sheet_1_New insights into the evaluation criteria for high-quality deep marine shale gas reservoirs in the Longmaxi formation: Evidence from organic matter pore development ch... by Boyuan Zhu (12754736)

“…Furthermore, the improved model decreased the relative error in predicting the OM porosity by about 32.5%. …”