Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress by Hammad, Ayat Samir

“…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. …”
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Image_3_Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids.tif by Qian Zhuang (621842)

“…GPs increased the hepatic expression of genes encoding the cytochrome P450 (Cyp) enzymes Cyp7a1, Cyp7b1, and Cyp8b1, while decreasing the hepatic expression of genes encoding the adenosine triphosphate-binding cassette (Abc) transporters Abcg5 and Abcg8. …”

DataSheet1_Integrative Analysis of Long- and Short-Read Transcriptomes Identify the Regulation of Terpenoids Biosynthesis Under Shading Cultivation in Oenanthe javanica.docx by Kai Feng (502124)

“…<p>Water dropwort (Oenanthe javanica) is a popular vegetable with high nutritional value and distinctive flavor. …”

Distinct small non-coding RNA landscape in the axons and released extracellular vesicles of developing primary cortical neurons and the axoplasm of adult nerves by Raquel Mesquita-Ribeiro (6818948)

“…Notably, although 5ʹ-tRHs compose the great majority of tRNA-derived fragments observed <i>in</i> <i>vitro</i>, a shift to 3ʹ-tRNAs is observed in mature axons <i>in</i> <i>vivo</i>.…”

Image_1_Optimization of tomato (Solanum lycopersicum L.) juice fermentation process and analysis of its metabolites during fermentation.pdf by Lei Zhao (144153)

“…Carbohydrates were fully retained at the end of fermentation.The content of galactitol increased from the initial 5.389 to 6.607 while the content of cytarabine decreased by 29% and uridine by 44%. …”

Table 1_Belimumab-driven reductions in retinal microvascular density assessed by optical coherence tomography angiography: insights from systemic lupus erythematosus patients.docx by Maierhaba Maitiyaer (18947791)

“…Linear regression showed a significant negative association between Belimumab treatment and parafoveal DCP-VD. …”

DataSheet_1_Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism.docx by Hao Cheng (103394)

“…<p>Ulcerative colitis (UC) is a chronic and recurrent inflammatory disorder in the gastrointestinal tract. …”

Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg by Mailén Rojo (10802556)

“…Introduction<p>Polycystic Ovary Syndrome (PCOS) affects 5-20% of reproductive-aged women. Insulin resistance (IR) is common in PCOS with consequent elevated risks of metabolic disorders and cardiovascular mortality. …”

Inflammation Enhances IL-2 Driven Differentiation of Cytolytic CD4 T Cells by Aspen M. Workman (525540)

“…IL-2 signaling was also necessary <i>in vivo</i> for inducing the Th1 phenotype and IFN-γ expression in CD4 T cells during influenza A (IAV) infection. In addition, GrB expression, as measured by mean fluorescent intensity, was decreased in CD25 deficient cells; however, the frequency of CD4 cells expressing GrB was unchanged. …”

Supplementary Material for: High expression of tetraspanin CD63 predicts poor prognosis in esophageal squamous cell carcinoma by Matsumoto Y. (2866151)

“…CD63 knockdown in ESCC cell lines resulted in a phenotype of decreased proliferative potential. …”

Psychosocial interventions for post-traumatic stress disorder in refugees and asylum seekers resettled in high-income countries: Systematic review and meta-analysis by Michela Nosè (2163970)

“…Narrative exposure therapy, a manualized short-term variant of cognitive behavioural therapy with a trauma focus, was the best-supported intervention (5 RCTs, 187 participants, SMD -0·78, 95% CI -1·18 to -0·38, <i>I</i>^<i>2</i> 37%; 95% CI 0 to 77). …”

The bursting of the Purkinje soma model is gated by the BK and SK conductances. by Michael D. Forrest (292801)

“…<i>Panel F scaling is encoded in its own scale bar (30 mV, 0.5 s); the scaling of all other panels is encoded in the scale at the bottom of the figure (30 mV, 20 ms)</i>.…”

DataSheet1_Population structure, genetic diversity and prolificacy in pishan red sheep under an extreme desert environment.PDF by Cheng-long Zhang (14833335)

“…The result showed that r² of PRS was 0.233 ± 0.280 in the range of 0–10 Kb and decreased with increasing distances. SMC++ tested that the Ne of PRS remained at 236.99 in recent generations. 184 genes were screened out under iHS 1% threshold, and 1148 genes were screened out with F_ST under the 5% threshold, and 29 genes were obtained from the intersection of the two gene sets. …”

Table_1_The Characteristics and Expression Profile of Peptidoglycan Recognition Protein 2 in the Accessory Nidamental Gland of the Bigfin Reef Squid During Bacterial Colonization.p... by Hau-Wen Li (841219)

“…Our recent study on bigfin reef squid (Sepioteuthis lessoniana) already showed that the ANG bacterial community shifts gradually and exhibits decreased diversity throughout maturation. This study further describes a potential role of an innate immunity-involved molecule, peptidoglycan recognition proteins (PGRPs), in the ANG of bigfin reef squid during bacterial transmission and colonization. …”

DataSheet_1_RNF135 Promoter Methylation Is Associated With Immune Infiltration and Prognosis in Hepatocellular Carcinoma.docx by Xiao Wang (19312)

“…RNF135 functions as a tumor suppressor and is involved in tumor immune microenvironment in HCC.…”

Data_Sheet_1_Identification, Characterization, and Expression Profile Analysis of the mTERF Gene Family and Its Role in the Response to Abiotic Stress in Barley (Hordeum vulgare L.... by Tingting Li (10553)

“…In this study, we identified 60 mTERFs in the barley genome (HvmTERFs) through a comprehensive search against the most updated barley reference genome, Morex V2. …”

Differential expression of VIM forms under time-dependent osmotic stress conditions. by Bettina S. Buchmaier (432890)

“…<p>Western blot analysis of cytoskeletal proteins during osmotic stress adaptation. A: TALH-STD cells were stressed with 30 mM glucose medium and tested for protein expression changes after 0, 24, 48, 72, and 96 h with antibodies against the indicated protein. …”

Switching of Electron and Ion Conductions by Reversible H₂O Sorption in n‑Type Organic Semiconductors by Haruka Abe (3174081)

“…The reversible H₂O adsorption into the crystals enhanced the electron mobility from 0.04 to 0.28 cm² V^–1 s^–1, whereas the K⁺ ionic conductivity decreased from 3.4 × 10^–5 to 4.7 × 10^–7 S cm^–1. …”

DataSheet1_Amplifying Flood Risk Across the Lower Yellow River Basin, China, Under Shared Socioeconomic Pathways.docx by Jinbo Song (4688455)

“…Under SSP126, SSP245, and SSP585 scenarios, the areas with increasing flood hazards during 2015–2045 accounted for 65.2, 69.0, and 64.5% of the entire YRB. In the spatial pattern, flood hazards decreased from southeastern to northwestern parts of the YRB. …”

Effects of the antifungal drugs myriocin, amphotericin B, and fluconazole on <i>Galleria mellonella</i> survival 24 and 48 h post-treatment. by Nadja Rodrigues de Melo (485602)

“…Effect of MYR at higher concentration (0.5 µg/ml) decreased the survival rate when compared with CA group (*p<0.001, n = 20). …”