DataSheet_1_Immunoregulatory effects of RGMb in gut inflammation.docx by Magdiel Pérez-Cruz (6422627)

“…Anti-RGMb mAb (9D1) treatment decreased IFN-γ and significantly increased IL-5 and IL-10 in the gut of the treated mice compared to the isotype control treated mice.…”

Downregulation of Protein Kinase CK2 Activity Facilitates Tumor Necrosis Factor-α-Mediated Chondrocyte Death through Apoptosis and Autophagy by Sung Won Lee (222509)

“…It should be clarified in the future if autophagy observed is a consequence versus a cause of the degeneration <em>in vivo.…”

Image_1_Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart.jpeg by Yamin Rao (13166352)

“…In our cohort, invasive pEMPD presented increased expression of androgen receptor and decreased MUC5CA expression, and these two changes might bring to the shift of invasive phenotype. …”

DataSheet1_Albuca Bracteata Polysaccharides Attenuate AOM/DSS Induced Colon Tumorigenesis via Regulating Oxidative Stress, Inflammation and Gut Microbiota in Mice.docx by Ziyan Qin (4058464)

“…In this study, we investigate the properties of polysaccharides of A. bracteate, named ABP. The average molecular weight of ABP was 18.3 kDa and ABP consisted of glucose, mannose, galactose, xylose, galacturonic acid, glucuronic acid at a molar ratio of 37.8:8:2.5:1.7:1:1. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…The median OS was not reached (95% CI: 13.27-NR), with a 1-year OS rate of 73.5% (95% CI: 60.4–89.3%). …”

Table_4_Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.xlsx by Wan-Chun Li (450324)

“…Loss of HK2 in HNSCC cells resulted in reduced cell (in vitro) and tumor (in vivo) growth, as well as decreased epithelial-mesenchymal transition–mediated cell movement; in contrast, HK2-deficient HNSCC cells exhibited greater sensitivity to chemotherapeutic drugs cisplatin and 5-fluorouracil but are more resistant to photodynamic therapy, indicating that HK2 expression could selectively define treatment sensitivity in HNSCC cells. …”

Table2_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4 by Yu Tina Zhao (3359159)

“…Western blotting was employed to determine active-caspase 3, annexin V, and HDAC4 expression. As compared to wild type H9c2 group, HDAC4 overexpression remarkably led to a great increase in cell death as evident by the increased lactate dehydrogenase (LDH) leakage, ratio of caspase-3-positive cells as well as the upregulated levels of active-caspase 3 and annexin V shown by western blot analysis. …”

Differential Effects of Short-Term Treatment with Two AT₁ Receptor Blockers on Diameter of Pial Arterioles in SHR by Sébastien Foulquier (138858)

“…In the first study, 4-month-old male SHR were treated with telmisartan (TELMI, 2 mg/kg per day) or candesartan cilexetil (CANDE, 10 mg/kg per day) and compared to vehicle treated SHR and normotensive WKY. In a second study, SHR were treated with CANDE, pioglitazone (a PPAR-gamma agonist, PIO 2.5 mg/kg per day) or CANDE+PIO, compared to TELMI. …”

DataSheet_1_Magnetic Resonance Imaging Correlates of Immune Microenvironment in Glioblastoma.pdf by Alessandro Salvalaggio (8780132)

“…MRI features may represent a novel tool for investigating the microenvironment of GBM.…”

Muscle oxygenation in vastus lateralis and gastrocnemius during incremental running exercise: effect of exercise intensity, VO2max, sex and age by Hugo Kerhervé (618369)

“…The aim of this study was to describe the effect of exercise intensity, maximum oxygen utilisation (V ̇O_2MAX), sex and age on vastus lateralis (VL) and gastrocnemius (Gn) muscle oxygenation measured using near-infrared spectroscopy (NIRS) during incremental running exercise to exhaustion, in a participant group having a large range of V ̇O_2MAX.…”

Data_Sheet_1_Involvement of Gut Microbiota in the Development of Psoriasis Vulgaris.doc by Chaonan Sun (4681345)

“…Passing flatus and constipation were significantly correlated with psoriasis (p < 0.05 in both cases). (2) The abundance of Ruminococcaceae family, Coprococcus_1 genus, and Blautia genus were decreased with psoriasis improvement (p < 0.05, respectively), which had been demonstrated significantly increased in psoriasis. (3) Mice receiving psoriatic microbes transplantation showed delayed recovery of psoriasiform dermatitis and less reduction of interleukin (IL)-17A than those receiving healthy microbiota or blank control (p < 0.05 and p < 0.01, respectively).…”

Data_Sheet_1_An Integrated Omics Approach Uncovers the Novel Effector Ecp20-2 Required for Full Virulence of Cladosporium fulvum on Tomato.docx by Mansoor Karimi-Jashni (12997986)

“…The Ecp20-2 gene encodes a small secreted protein of 149 amino acids with a predicted signal peptide of 17 amino acids. …”

Data_Sheet_1_New insights into the evaluation criteria for high-quality deep marine shale gas reservoirs in the Longmaxi formation: Evidence from organic matter pore development ch... by Boyuan Zhu (12754736)

“…Furthermore, the improved model decreased the relative error in predicting the OM porosity by about 32.5%. …”

Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment. by Kashir, Junaid

“…Male recruitment criteria required a minimum sperm count of 5 × 10 spermatozoa/mL, while all female patients included in this study yielded at least five oocytes for treatment. …”
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DataSheet_1_Single-cell RNA transcriptomics reveals differences in the immune status of alcoholic and hepatitis B virus-related liver cirrhosis.docx by Pengpeng Zhang (583380)

“…This study explored the differences in the immune status of alcoholic and HBV-related liver cirrhosis.</p>Methods<p>A total of 15 human liver samples from the Third Xiangya Hospital of Central South University, including five healthy controls (HC group), five alcoholic cirrhosis patients (ALC group), and five HBV-related cirrhosis patients (HBV group) were used. …”

An overview of study characteristics. by Akhmedkhan Dubayev (17879559)

“…</p><p>Results</p><p>Twenty-five studies were included (5 randomized controlled trials, 20 non-randomized controlled trials). …”

Numerical model. by Hai Rong (18422937)

“…When the lateral stress coefficient and joint angle are the same, an increase in initial in-situ stress results in a reduction in the area of the blasting damage zone. (2) Under the same initial in-situ stress conditions, the area of the blasting damage zone initially increases and then decreases with an increasing joint angle. …”

Factors influencing LVC in healthy adults (Werden Abrams et al., 2023) by Sophia Werden Abrams (16972306)

“…</p><p dir="ltr"><b>Method:</b> A retrospective analysis of 195 healthy adults (85 men, 110 women; age range: 21–89 years) who participated in a videofluoroscopic swallowing study was completed. …”

Summary of NOS bias assessments. by Akhmedkhan Dubayev (17879559)

“…</p><p>Results</p><p>Twenty-five studies were included (5 randomized controlled trials, 20 non-randomized controlled trials). …”