Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner by Khondoker Alam (1443499)

“…Pretreatment with bortezomib (50–250 nM, 2–7 h) significantly decreased transport of [³H]CCK-8, a specific OATP1B3 substrate, in HEK293-OATP1B3 and human sandwich-cultured hepatocytes (SCH). …”

PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine. by Shaily Malik (226661)

“…<p>(A) Human neurons were treated with 100 ng/ml Tat and/or 100 nM morphine for 12 hours with or without pre-treatment with 40 ng/ml PDGF-BB. …”

n-3 PUFA depletion leads to decreased hepatic fatty acid oxidation and increased TG secretion and synthesis. by Barbara D. Pachikian (155501)

Position of the residues on the surface of (H1N1) A/PR/8/34 influenza hemagglutinin trimer decreasing the binding of PN-SIA28. by Nicola Clementi (174058)

Data_Sheet_1_The Contribution of Decreased Muscle Size to Muscle Weakness in Children With Spastic Cerebral Palsy.docx by Britta Hanssen (4898155)

“…Selective motor control (SMC) was assessed on a 5-point scale for the children with SCP. First, the anthropometrics, strength, and muscle size parameters were compared between the cohorts. …”

V5-SgG2 transfection in the epidermis modifies the termination site of peptidergic FNE. by Jorge Rubén Cabrera (685511)

Adjusted odds ratios and 95% confidence intervals for the association of pancreatic cancer with a 1 kg/m2 decrease in body mass index (BMI) between cases and controls (blue circles) and a 1 mmol/mol increase in glycated haemoglobin (HbA1c) (green squares) from 5 years before pancreatic cancer diagnosis. by Agnieszka Lemanska (13911532)

Mcl-1 protein expression is decreased by internal dsRNA and its modulation regulates beta cell apoptosis. by Maikel L. Colli (179059)

Frequency of IL-17 and/or IL-22 expressing mucosal CD4+T cells decreases by progression of Fiebig stage. by Alexandra Schuetz (327671)

“…<p>To quantify the expression of Il-17 and IL-22 in CD4+T cells, mucosal and peripheral mononuclear cells were stimulated for 5 hours with 40 ng/mL PMA and 1 µM Ionomycin. Gating strategy of sigmoid colon Th17 and Th22 CD4+T cells is shown for a FI subject (<b>a</b>) and representative flow cytometry plots including unstimulated controls (unstim) gated on CD4+T cells showing expression of IL-17 and/or IL-22 in FI (<b>b</b>), FIII (<b>c</b>) and FV (<b>d</b>) in the sigmoid colon. …”

Decreasing ShcA expression enhances TGF-β-induced Smad signaling. by Baby Periyanayaki Muthusamy (838234)

“…Note the enhanced basal pSmad3 or pSmad2 levels in cells transfected with ShcA siRNA. ShcA immunoblotting reveals decreased ShcA levels in cells transfected with ShcA siRNA, and GAPDH immunoblotting serves as loading control. …”

Variable importance plot (mean decrease accuracy and mean decrease Gini). by Fernando Martinez-Taboada (8655132)

Administration of anti-CD25 antibody decreases the early and late organ fungal burdens of resistant and susceptible mice. by Maíra Felonato (296591)

High concentrations of UA lead to decrease of TRACP 5b levels. by Zhi-Qi Wu (847506)

Frequencies of MAIT cells are decreased in patients with CHCV, HIV and AHCV/HIV co-infections compared to healthy individuals. by Michelle Spaan (3152985)

Serum IgA samples by COVID-19 disease severity (mild, moderate, severe) binding to the various SARS-CoV-2 protein antigens compared to no disease (NC). by Marie Le Berre (6299012)

Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis by Iveta Yotova (451965)

“…Genes found to have DM included examples encoding transporters (<i>SLC22A23</i>), signaling components (<i>BDNF</i>, <i>DAPK1</i>, <i>ROR1</i>, and <i>WNT5A</i>) and transcription factors (<i>GATA</i> family, <i>HAND2</i>, <i>HOXA</i> cluster, <i>NR5A1</i>, <i>OSR2</i>, <i>TBX3</i>). …”

Lethal SARS-CoV-2 infection induced autoantibody to ANXA2 production and dysregulated ANXA2 system in AC70 hACE2 Tg mice. by Aleksandra K. Drelich (18874696)

“…<p>(<b>A</b>) Gamma irradiated EDTA-plasma samples collected from Mock mice and at 4 d.p.i. with 10⁵ TCID₅₀ of SARS-CoV-2 were analyzed by ELISA assay. …”

Blocking CD88 decreased ANCA antigen translocation, ANCA-induced respiratory burst and degranulation in C5a-primed neutrophils. by Jian Hao (160736)

“…C and D: blocking CD88 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. …”

Four representative proteins, PDIA1, ACADM, RUVBL1, PRDX2 identified using 2-DE profiling were either increased or decreased in a concentration responsive manner. by Yue Ge (350900)

Inorganic salts and intracellular polyphosphate inclusions play a role in the thermotolerance of the immunobiotic <i>Lactobacillus rhamnosus</i> CRL 1505 by María A. Correa Deza (4097602)

“…The strain displayed a high intrinsic thermotolerance (55°C, 20 min); however, after 5 min at 60°C in phosphate buffer a two log units decrease in cell viability was observed. …”