Tranilast decreases RANKL-induced ROS level. by Tien Van Phan (583324)

Fig 5 - by Zhi Zhang (55283)

Data_Sheet_1_Determining 5HT7R’s Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine.pdf by Lu Liu (171341)

“…<p>Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT₇ receptor (5-HT₇R) has been reported to play an excitatory role in neuronal systems and regulate hyperalgesic pain and neurogenic inflammation. 5-HT₇R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated kinase₁_/₂ (ERK₁_/₂)-mediated signaling pathways, which mediate sensitization of nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). …”

Knockdown of OAMB or 5-HT_1A in IPCs resulted in opposite phenotypes in a capillary feeding assay (CAFE). by Jiangnan Luo (218899)

“…<p><b>A</b> Diminishing 5-HT_1A in IPCs (<i>Dilp2</i>-Gal4><i>5-HT_1A</i>-RNAi) significantly decreases food intake only during day 2. …”

Table_5_Tramadol’s Inhibitory Effects on Sexual Behavior: Pharmacological Studies in Serotonin Transporter Knockout Rats.PDF by Diana C. Esquivel-Franco (5455082)

“…To investigate whether other mechanisms contribute to the inhibitory effects, WAY100,635, a 5-HT_1A receptor antagonist and naloxone, a μ-opioid receptor antagonist, were tested on sexual behavior together with tramadol. …”

Binding sensogram (a) showing decrease in frequency of crystal immobilised with 1.5 M short aptamer exposed to different concentrations of heparanase. by Suzanne C. Simmons (319222)

“…<p>Higher concentrations of heparanase exhibited a greater decrease in frequency. Binding and regeneration sensogram (b) for addition of 800 nM heparanase to a quartz crystal immobilised with 1.5 M short aptamer. …”

Sildenafil decreases intestinal transit time in a DSS-recovery model of IBS. by Sarah K. Sharman (3966476)

NSAIDs decrease the viability of ovarian cancer cells in a dose-dependent manner. by Blanca L. Valle (406582)

A low dose of BTZ decreases proteasome activity with no effect on cell viability. by A. L. Furfaro (2587792)

hMp84 stimulates the formation of Reactive Oxygen Species (ROS) and induces oxidative alterations of phospholipids in HT-144 melanoma cells. by Daniele Moretti (379766)

Adenylate cyclase activation does not cause translocation of PKC Apl II in response to 5HT in Sf9 cells. by Carole A. Farah (336422)

“…<p><b>A)</b> Sf9 cells were cotransfected with mRFP-PKC Apl II along with either eGFP-5HT_4Apl (n = 17), eGFP-5HT_7Apl (n = 15) or eGFP-5HT_2Apl (n = 9). …”

PTH decreased cell apoptosis in a Flt-3L expanded population. by Flavia Q. Pirih (360515)

Treatment with the antioxidant <i>N</i>-Acetyl-L-Cysteine (NAC) or with the p53 inhibitor, Pifithrin-α (PFT), prevents ROS formation in hMp84-overexpressing A375 cells. by Daniele Moretti (379766)

Treatment with the antioxidant <i>N</i>-Acetyl-L-Cysteine (NAC) or with the p53 inhibitor, Pifithrin-α (PFT), prevents cell death in hMp84-overexpressing A375 cells. by Daniele Moretti (379766)

CcnA mutation of Loop A decreases the interaction with the 5′ UTR of P2-<i>ctrA</i> mRNA and 5′ UTR of <i>gcrA</i> mRNA. by Wanassa Beroual (5314028)

AEA decreases mPGES-1 mRNA and protein levels. by Claudia A. Vercelli (284964)

Production of O₂^ꜙ, NO and cyclic GMP by 5-HT. by Marie Billaud (261506)

“…<p>A, O₂^░ production was measured by EPR spectrometry in the absence or in the presence of 5-HT 100 µM (black column and white column respectively). …”

Rate-limiting enzymes tyrosine hydroxylase (catecholamines) and tryptophan hydroxylase (5-HT) post-stress. by C. Brad Wilson (468614)

“…<p>Tyrosine hydroxylase elevation in the PFC (A) and hippocampus (B) substantiated the findings of elevated levels of NE and DA, while down-regulated tryptophan hydroxylase in the PFC (C) and hippocampus (D) confirmed decreased levels of 5-HT. …”

5-HT-induced cardiomyocyte injury required the presence GC or NE <i>in vitro</i>. by Wang Xinxing (523139)

“…<b>A.</b> The cell viability of cardiomyocytes treated with 10⁻⁸ M 5-HT and 10⁻⁶ M GC decreased significantly compared with the control. …”

5-HT₇Dro knock-down results are consistent with pharmacological studies. by Jaime Becnel (218896)

“…C) The activity of male flies carrying either the 5-HT₇Dro-GAL4 element (GAL4, white bar), the UAS-sym-p5-HT₇RNAi element (UAS-RNAi, black bar), or both (F1, gray bar) was measured using the DAMS system for five days. …”