NBCe1 protein expression regulation by D₁-like (D₁R and D₅R) dopamine receptor agonist in hRPTCs carrying wild-type (WT) <i>SLC4A5</i>. by John J. Gildea (845025)

“…<p>NBCe1 protein expression is decreased following an increase in intracellular sodium (↑Na⁺) (10 μmol monensin/L, 24 h) (N = 4, *P<0.001 vs VEH, one-way ANOVA, Tukey’s test) in WT <i>SLC4A5</i> hRPTC. …”

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

CD5-CK2 Signaling Modulates Erk Activation and Thymocyte Survival by Carlos A. Mier-Aguilar (3605360)

“…Using a gene-targeted mouse in which the CD5-CK2BD is selectively ablated (CD5-ΔCK2BD), we determined that loss of function of CD5-CK2 signaling in a MHC-II selecting TCR transgenic (OT-II) mouse resulted in decrease in double positive (DP) thymocytes, which correlated with enhanced apoptosis. …”

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity-5 by Rodrigo A Fuentealba (77901)

“…</p><p></p>d triangle), 10 μg (open triangle) or 20 μg (open inverted triangle) of an ApoER2 coding plasmid were incubated with 1 nM I-labeled-anti-HA IgG or 5 nM I-labeled-diFeTf for 1 h at 4°C and then shifted to 37°C for the indicated times. …”

Genes regulated by NRF2, XBP1, PPARA or PPARG that are down- or up- regulated in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

Relative mRNA levels of DNA methyltransferases (<i>Dnmt1</i>, <i>Dnmt3a</i>, and <i>Dnmt3b</i>; a) and microRNAs (<i>mir-29b</i>, <i>mir-148a</i>, and <i>mir-152</i>; b) in porcine... by Shuang Liang (211832)

Subjects:

ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. by Richard Junior Zapata Dongo (17912565)

Lack of PD-L1 expression by host tissues increases numbers of activated donor T cells but decreases donor Tregs in spleen. by Mohammad S. Hossain (415643)

Y86 is critical for SERINC3/5 antagonism by SIVcol Nef. by Dorota Kmiec (5646374)

Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

Subjects:

Preserved NSS at 2 and at 24 hours following ischemia and decreased infarct volume in PAR1 KO mice 24 hours following ischemic stroke. by Efrat Shavit-Stein (3186678)

“…(C) Total infarct volume is significantly lower in PAR1 KO mice compared to control (t-test, WT = 6, PAR1 KO = 6). (D) Infarct volume decreases as a function of distance from the ischemic core (slices #5&6). …”

Gefitinib + Capmatinib decrease proliferation of <i>v-ras</i>^<i>Ha</i>-transduced wild type and <i>Tpl2</i>^-/- keratinocytes. by Mary B. Kelley (12290071)

NBCe1 and NBCe2 protein and mRNA expression in hRPTCs carrying wild-type (WT) or homozygous variant (HV) <i>SLC4A5</i>. by John J. Gildea (845025)

“…<b>D) <i>SLC4A4</i> mRNA.</b> <i>SLC4A4</i> mRNA is decreased following an increase in intracellular sodium (monensin, 1 μmol/L, 24 h) (↑Na⁺) only in WT <i>SLC4A5</i> hRPTCs (N = 9, *P<0.05 vs. …”

Interactions between E1A and PKA are required for full HAdV-5 progeny production. by Cason R. King (2633092)

“…<p>A549 cells were treated with control siRNA or siRNA specific for PKA subunits and infected with either WT HAdV-5 or a virus encoding E1A unable to bind PKA (Δ4–25). …”

<i>Ang1</i>-KO mice develop more severe colitis compared to WT mice. by Alexander Hu (14755811)

Increased accumulation of mutant huntingtin aggregates and decreased mobility of autophagosomes in the axon of AP-4 ε KO hippocampal neurons. by Raffaella De Pace (5147120)

Comparison of the Th2 cytokine expression level after treatment with KA/E2 in WT and TLR2 KO mice. by Mi-Kyung Park (56053)

Acetylcholine-induced NO- and EDHF-mediated relaxations decrease with increasing age. by Noureddine Idris Khodja (331400)

ASO treatment suppresses the palbociclib-mediated induction of MEG3 and decrease in cell proliferation in SK-MES-1 cells. by Traci L. Kruer (3342425)

Mfsd2a KO mice have decreased liver TG with normal liver metabolism. by Justin H. Berger (297156)