Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

“…The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”

CDA-2 decreases pulmonary inflammation. by Xuan Wang (55634)

Decrease of bnAb activity during cell-cell transmission is variable and strain-dependent. by Lucia Reh (546554)

Serum estradiol concentrations in study (n = 9) and control (n = 5) bitches during the luteal phase, from days 8 to 27 after the estimated LH peak. by Kamil Kacprzak (713647)

Palmitate decreases adiponectin expression and secretion. by Shakun Karki (194655)

Serum progesterone concentrations in study (n = 9) and control (n = 5) bitches during the luteal phase, from days 8 to 27 after the estimated LH peak. by Kamil Kacprzak (713647)

EMBS-treated cells undergo apoptosis correlated with decreased cell viability, metabolic activity and mitochondrial membrane potential. by Michelle Helen Visagie (3927308)

Jasplakinolide decreased late EPC proliferation. by Xiaoyun Zhang (115529)

Use of a multiplex HTG assay to identify confirmed hit siRNA pools that decrease expression of key gluconeogenic genes in addition to G6PC. by Ruojing Yang (323580)

Isoflurane decreased miR-214. by Hailiang Yan (284342)

“…(<b>E</b>) miR-214 decreased Bax expression in a dose-dependent manner. …”

Osr1 heterozygous mice experienced decreased bile acid synthesis in the liver. by Ernest C. Lynch (12769954)

“…<p>(A). Osr1 male mice had a decreased trend of hepatic bile acid compared to WT mice. …”

Neuroapoptosis decreases following CO exposure. by Ying Cheng (288456)

LMP1 decreases mitochondrial respiration. by Michael Hulse (5932112)

Real-time PCR confirmation of randomly selected genes whose expression levels were either increased (red) or decreased (green) by a specific endoxifen concentration. by John R. Hawse (227611)

“…Darkly shaded bars depict relative fold changes from E₂ (10 nM), TAM (300 nM), 4HT (7 nM) and NDT (700 nM) treated cells (combo/dashed line) as detected by microarray analysis while lightly shaded bars depict fold change as detected by RT-PCR analysis. …”

Step Width, Step Length, and Step Time. by Mengnan Wu (769253)

Activation of GluR5 increased neuronal excitability in interneruons but decreased excitability in pyramidal neurons. by Long-Jun Wu (47043)

“…Resting membrane potential for this neuron was −66.6 mV and the holding current was 66.9 pA. (H) Pooled data showed that ATPA (3 µM) increased firing rate of interneurons (n = 6) while decreased that of pyramidal neurons (n = 5). …”

The saturated fatty acid palmitate decreases viability and induces apoptosis in HUVECs. by Dustin M. Lee (8207457)

A decreased yield of RNP1, RNP2 and RNP5 formation in the presence of protein aGAR1 is counteracted by RNA-S by Bruno Charpentier (9519)

A Bcl-2-BH4 double-glycine variant (I14G/V15G) has a decreased by Giovanni Monaco (452223)

Absence of PML decreases the co-localization of DAXX and ATRX but not HIRA and UBN1 with latent/quiescent HSV-1 genomes. by Camille Cohen (2440810)