Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Tun increases mitochondrial fission, inflammatory cell infiltration, and decreased ER-mitochondria interaction in neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…The decreased expressions of GRP75 (0.5±0.2-fold, p = 0.006767, n = 5) and acyl-CoA synthetase long-chain family member 4 (ASCL4; 0.3±0.1-fold, p<0.001, n = 5) indicate a decreased interaction between ER and mitochondria by Tun. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Mean (± standard error) of deermouse visits to the foraging stations and mean (± standard error) number of intra- and interspecific interactions of deermice (DM) among treatments (... by André V. Rubio (4594702)

The proportional decrease in chamber area with depth of nests is similar no matter what the colony size by Walter R. Tschinkel (2765)

No discernible effect of high-dose 5-HT_2AR blockade on error rates in the reward-size task. by Yukiko Hori (299784)

Sost and Sclerostin Expression are Decreased and Wnt Signaling is Increased in DMP1-caPTHR1 Transgenic Mice. by Charles A. O'Brien (271071)

Mean ± SD values for the parameters found when Eq. 8 (S1 Appendix) was used to model the relationship between time duration of movement (<i>t</i>_<i>dur</i>) and the weig... by Kai Roecker (847195)

Dose-response curves showing the decrease in total abundance of bacterial <i>amo</i>A gene over 28 d. by Casey L. Doolette (3092499)

Ovariectomy (OVX) induced decrease in hexokinase expression and activity: prevention by 17β-estradiol. by Fan Ding (302565)

“…<p>A. In female 3×TgAD brains, OVX induced a significant decrease in protein expression of hexokinase 2 (*, P<0.05, bars represent mean value±SEM, n = 5−6), which was partially prevented by E2 treatment. …”

Effect of ursodeoxycholic acid (150 mg/kg, p.o.) and fenofibrate (100 mg/kg, p.o.) on body weight, serum parameters and blood pressure in rats administered fructose. by Amr A. A. Mahmoud (627688)

Infection-induced decrease of early myeloid progenitors is critically dependent on IFN-γ signaling. by Nikolai N. Belyaev (419166)

M2 macrophages decrease alkaline phosphatase activity through Wnt signalling pathways. by Jesús Cosín-Roger (123861)

Ameliorative effect of yokukansan on glutamate-induced decrease in GSH levels in PC12 cells. by Hitomi Kanno (584976)

LiCl, TSA, and MTR decrease polyQ mediated ASH neuronal death. by Cindy Voisine (30589)

Decrease of locomotor activity in <i>Auts2</i> mutant mice during habituation. by Kei Hori (840871)

“…<p>(A) Spontaneous locomotor activity for habituation to the novel environment was measured every 5 min for 60 min. …”