Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

Subjects:

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity-5 by Rodrigo A Fuentealba (77901)

“…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”

PLD1 inhibition decreases the c-Myc-dependent dNTP biosynthetic transcriptional program. by Harry E. Taylor (596259)

VEGFR2/VEGF-A ligand binding decreased ranibizumab and aflibercept mediated CCL2, CCL5, and CX3CL1 mRNA and protein levels in HCAECs. by Clare Arnott (2557705)

Modifying pregnenolone to decrease its lipophilicity results in decreased cellular uptake. by Jeffrey M. McManus (7512926)

PCA2 decreased LPS-induced ROS generation. by Qin-Qin Wang (9211958)

ApoE3 decreases Rho activity and F-actin stress fibers in human VSMCs. by Bernadette Y. Hsu (753458)

Intracellular levels of HSPG core proteins, HS and HPSE are decreased in ER stressed MIN6 cells. by Sarita Dhounchak (10924448)

I348T increases H77 entry dependency on SR-BI, while T385P decreases H77 entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

Claudin V is decreased following infection with Mtb. by Amanda S. Latham (12093638)

“…Exposure to Mtb H37Rv and HN878 decreased claudin V expression compared to uninfected controls in the frontal cortex (E), cerebral nuclei (J), brain stem (O), thalamus (T), and hippocampus (Y). …”

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The receptors were activated by EC₅₀ concentrations of glutamate with saturating concentration (100 μM) of glycine at holding potential of -40 mV. The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

<i>btuE</i> expression results in decreased intracellular ROS. by Felipe A. Arenas (23050)

ATRA decreases mRNA expression of HO-1, GCLM and x-CT and lowers GSH level in BTZ-treated cells. by A. L. Furfaro (2587792)

<i>Furin</i> mutant hearts show a decreased in the number of phospo-Smad positive cells at the AV junction. by Laurent Dupays (2940330)

The effect of ML264 (Klf5 inhibitor) on aneurysm formation induced by Ang II infusion in the early and late stages. by Dong Ma (584680)

Subjects:

ATRA decreases the binding of Nrf2 to ARE sequences in the promoter regions of HO-1, GCLM and x-CT in BTZ-treated cells. by A. L. Furfaro (2587792)

PGE₂ signals through <i>Ptger2</i> to decrease <i>Sost</i> expression. by Damian C. Genetos (325684)

Decreased responsivity to mechanical stimuli during DRN 5-HT neurons photostimulation. by Guillaume P. Dugué (620333)

Substrate translocation via Mep2^H194E induces a pH decrease. by Ana Sofia Brito (8463537)

Flies decrease the level of aggression as the availability of food resource increases. by Rod S. Lim (622045)

“…Aggression initially increases from 0 mm² to 707 mm² and decreases as the size of food increases further. …”