Transcriptional repression of synapse-related genes and a decrease in spine density by AAV-hGATA1 and AAV-hGATA2 in DG of the rat hippocampus. by Miyeon Choi (648726)

“…(g) Representative images are shown of high-magnification Z-stack projections of apical tuft segments of GFP(+) DG granule cells from AAV-ctl, AAV-hGATA1 and AAV-hGATA2-injected rats. (h) Density of dendritic spines (arrowheads) was significantly decreased in AAV-hGATA1- and AAV-hGATA2-injected rats compared with AAV-ctl-injected rats (a main effect of virus, <i>F</i>_2,13 = 12.9, <i>P</i><0.0001; AAV-hGATA1: <i>F</i>_1,10 = 21.15, <i>P</i> = 0.0009; AAV-hGATA2: <i>F</i>_1,7 = 5.63, <i>P</i> = 0.04). …”

Metformin lotion decreases collagen III levels in the wounded skin of rats after 10 days of wound healing. by Jianying Zhang (256508)

Metformin lotion decreases collagen III levels in the wounded skin of rats after 10 days of wound healing. by Jianying Zhang (256508)

Calcineurin acts as a Ca²⁺ sensor for metamodulation of LP I_h in 5nM DA. by Wulf-Dieter C. Krenz (693267)

“…Experiments were performed as described for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117965#pone.0117965.g005" target="_blank">Fig. 5</a> using the calcineurin inhibitor, FK506. …”

Subgroup analysis of eGFR based on pump type. by Mohamed R. Abdelraouf (21501468)

“…The analysis showed that pulsatile perfusion led to a significant decrease in creatinine level [MD = −0.14, 95% CI (−0.24, −.04), P < 0.004], lactate level [MD = −8.21, 95% CI (−13.16, −3.25), P < 0.001], hospital stay [MD = −1.38, 95% CI (−2.51, −0.25), P = 0.016], ICU stay [MD = −0.47, 95% CI (−0.82, −0.13), P = 0.007], intubation time [MD = −3.73, 95% CI (−5.42, −2.04), P < 0.001], and increase in creatinine clearance [MD = 10.08, 95% CI (3.36, 16.80), P < 0.003]. …”

Transient increase of DN1 and decrease of DN2, DN3 showed in <i>the Foxn1</i>^<i>lacZ</i> thymus. by Shiyun Xiao (75798)

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…In this study, we employed all-atom molecular dynamics simulations to investigate the impact of different membrane compositions on the conformational dynamics of the NKG2A/CD94/HLA-E immune receptor complex, a key negative regulator of natural killer cell cytotoxic activity. …”

Pravastatin increases cyclin D1 expression but prevents passage through S-Phase in NSPCs. by Ross A. Carson (5184512)

Statins alter mRNA expression in differentiating NSPCs through a non-CBP dependent mechanism. by Ross A. Carson (5184512)

Schematic diagrams of (A) fiber developmental stages and activity of six cotton fiber specific genes during fiber development and (B-E) the pCambia binary vectors and cotton fiber... by Junping Chen (182808)

Decreased levels of Fance transcription in homozygous mutant males. by Chun Fu (2553043)

Image2_Repression of enhancer RNA PHLDA1 promotes tumorigenesis and progression of Ewing sarcoma via decreasing infiltrating T‐lymphocytes: A bioinformatic analysis.TIF by Runzhi Huang (7428713)

“…External validation based on multidimensional online databases and scRNA-seq analysis were used to verify our key findings.</p><p>Results: A six-different-dimension regulatory network was constructed based on 17 DEeRNAs, 29 DETFs, 9 DETGs, 5 immune cells, 24 immune gene sets, and 8 hallmarks of cancer. …”

Table2_Repression of enhancer RNA PHLDA1 promotes tumorigenesis and progression of Ewing sarcoma via decreasing infiltrating T‐lymphocytes: A bioinformatic analysis.DOCX by Runzhi Huang (7428713)

“…External validation based on multidimensional online databases and scRNA-seq analysis were used to verify our key findings.</p><p>Results: A six-different-dimension regulatory network was constructed based on 17 DEeRNAs, 29 DETFs, 9 DETGs, 5 immune cells, 24 immune gene sets, and 8 hallmarks of cancer. …”

DataSheet1_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter prot... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

Image4_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter protein... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

Image3_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter protein... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

Image1_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter protein... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

Image6_Assessment of the effect of the SLC5A2 gene on eGFR: a Mendelian randomization study of drug targets for the nephroprotective effect of sodium-glucose cotransporter protein... by Gailing Liu (19503148)

“…This suggests that a 1-SD increase in HbA1c levels, regulated by the SLC5A2 gene, is associated with decreased eGFR. …”

SARS-CoV-2 infected K18-hACE2-Tg-mouse brain. by Motoki Imai (7324697)

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)