Rat tickling: A systematic review of applications, outcomes, and moderators by Megan R. LaFollette (3911140)

“…The most common method used for tickling was cycling through 15 seconds of tickling and 15 seconds of rest for 2 minutes for 3 to 5 days. Experiments with a control for tickling (N = 22) showed that tickling increases positive vocalization, approach behavior, decreases anxiety measures, improves handling, and in some cases decreases stress hormones. …”

Data supplement from Injury-mediated decrease in locomotor performance increases predation risk in schooling fish. by J. Krause (2155690)

Statistical code from Injury-mediated decrease in locomotor performance increases predation risk in schooling fish. by J. Krause (2155690)

Fig 5 - by Lingling Shen (1552231)

AMPK activators reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

“…<p>(A) Representative western blot images (upper) and summarized data (lower) showing the effects of AICAR (n = 5 for each group) (A), ASP (n = 4 for each group) (B), and MET (n = 7 for each group) (C) on DEX-induced decreases of GR and pAMPK in cultured astrocytes. …”

Exposure to glucocorticoids decreases the levels of pAMPK and GR in cultured rat prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

FK866 treatment causes a time dependent decrease in cellular NAD⁺/NADH and NADP⁺/NADPH content. by Gerda Venter (559404)

Decreased expression of SMAD1/5/8 and VEFG in the Botox injected side MCC and subchondral bone. by Eliane H. Dutra (3207312)

Fig 5 - by Alireza Latifi (14593561)

Impairment of IL-2 responses correlate with lower CD25 expression and decreased IL-7 responses. by Florence Bugault (278171)

Meta data to Fig 2. by Xiaowen Jiang (8291814)

“…Thus, we provide a mechanism for how retinoic acid via <i>rcan2</i> can regulate K⁺-channel activity to scale a vertebrate appendage via intercellular Ca²⁺ signaling.…”

Meta data to S2 Fig. by Xiaowen Jiang (8291814)

“…Thus, we provide a mechanism for how retinoic acid via <i>rcan2</i> can regulate K⁺-channel activity to scale a vertebrate appendage via intercellular Ca²⁺ signaling.…”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists by Dilip K. Tosh (1668115)

“…In an effort to increase OR and decrease AR affinity by structure activity analysis of this series, antagonist activity at κ-(K)­OR appeared in 5′-esters (ethyl <b>24</b> and propyl <b>30</b>), which retained TSPO interaction (μM). 7-Deaza modification of C2-(arylethynyl)-5′-esters but not 4′-truncation enhanced KOR affinity (MRS7299 <b>28</b> and <b>29</b>, <i>K</i>_i ≈ 40 nM), revealed μ-OR and DOR binding, and reduced AR affinity. …”

Silencing of Rac1 and IQGAP1 decreases HPAEC migration in an <i>in vitro</i> scratch assay. by Evgeny V. Berdyshev (307465)

Fluoxetine decreases TOPFlash firefly luciferase reporter activity. by Kentaro Miyamoto (123271)

Intracellular levels of HSPG core proteins, HS and HPSE are decreased in ER stressed MIN6 cells. by Sarita Dhounchak (10924448)

Screening Sheet: A sheet that contains the full screening process that we used to include or exclude any study. by Mohamed R. Abdelraouf (21501468)