A low dose of BTZ decreases proteasome activity with no effect on cell viability. by A. L. Furfaro (2587792)

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”

Fully Transparent and Rollable Electronics by Mallory Mativenga (1681909)

“…For handling purposes, carrier glass is used during fabrication, together with a very thin (∼1 nm) solution-processed carbon nanotube (CNT)/graphene oxide (GO) backbone that is first spin-coated on the glass to decrease adhesion of the CPI to the glass; peel strength of the CPI from glass decreases from 0.43 to 0.10 N/cm, which eases the process of detachment performed after device fabrication. …”

S5 Fig - by Xinyue Yang (629144)

Bioavailable Soil Phosphorus Decreases with Increasing Elevation in a Subarctic Tundra Landscape by Andrea G. Vincent (543626)

“…We hypothesized that the concentration of labile P fractions would decrease with increasing elevation (and thus declining temperature), but would be lower in meadow than in heath, given that N to P ratios in meadow foliage are higher. …”

Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism by Qing-Yun Guo (2007082)

“…However, the mechanisms by which GABAergic system dysfunctions induce the pathophysiology of ASD remain unclear. We previously demonstrated that a selective type I 5α-reductase inhibitor SKF105111 (SKF) induced ASD-like behaviors, such as impaired sociability-related performance and repetitive grooming behaviors, in male mice. …”

Data_Sheet_1_Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity.d... by Chantal C. Clark (10684632)

PEGylated pUR4/FUD peptide inhibitor of fibronectin fibrillogenesis decreases fibrosis in murine Unilateral Ureteral Obstruction model of kidney disease by Bianca R. Tomasini-Johansson (5892587)

“…Decreased fibronectin was accompanied by a decrease in collagen and leukocyte infiltration. …”

PTH decreased cell apoptosis in a Flt-3L expanded population. by Flavia Q. Pirih (360515)

CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis by A. Nonino (6072632)

Table_1_v2_A long waiting time from diagnosis to treatment decreases the survival of non-small cell lung cancer patients with stage IA1: A retrospective study.docx by Bin Liu (5899)

“…After adjusting for other confounders, the waiting time was identified as an independent prognostic factor.</p>Conclusions<p>A long waiting time before treatment may decrease the survival of stage IA1 NSCLC patients. …”

Pathways regulating decreased soil respiration with warming in a biocrust-dominated dryland by Pablo García-Palacios (3591629)

Raw data V-trial. by Torsten Schober (20485754)

“…Empirical models for the relationships between the investigated plant traits and PD/DVP were created using linear regression analysis preceded by a lack-of-fit test. An increase in PD led to a linear decrease in inflorescence yield per plant (<i>p</i> = 0.02), whereas a positive linear relationship was found for inflorescence yield (<i>p</i> = 0.0001) and CBD yield (<i>p</i> = 0.0002) per m². …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

CcnA mutation of Loop A decreases the interaction with the 5′ UTR of P2-<i>ctrA</i> mRNA and 5′ UTR of <i>gcrA</i> mRNA. by Wanassa Beroual (5314028)

The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes by Marie Neergaard Harder (232759)

“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”

AEA decreases mPGES-1 mRNA and protein levels. by Claudia A. Vercelli (284964)

Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria by Patricia A. Reis (109310)

SH-SY5Y cells are responsive to acute insulin stimulation and altered insulin signaling impacts choline uptake by CHT. by Katherine J. Fishwick (768451)

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