Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease by Christine M. LaPash Daniels (796881)

“…Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. …”

<i>SIRT6</i> Minor Allele Genotype Is Associated with >5-Year Decrease in Lifespan in an Aged Cohort by Mindi J. TenNapel (679433)

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. by Dong Ma (584680)

Subjects:

Arginine supplementation decreases the inhibitory effect exerted by 5-flucytosine in <i>C</i>. <i>glabrata</i>. by Catarina Costa (322963)

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf by Marta Díaz (337207)

“…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10¹¹vs 5.6x10¹¹ particles/mL, respectively; p=0.01] and 7 [6.3x10¹¹vs 6.8x10¹¹ particles/mL, respectively; p=0.006]. …”

Data_Sheet_2_Applying the Toyota production system to decrease the time required to transport patients undergoing surgery from the general ward to the operating room and reviewing... by Chien-Chung Lin (244489)

“…The time spent on elevator transport decreased by 44.4%. We developed a process for future use based on information-assisted patient and staff identification. …”

Image_5_Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue.jpeg by Vinit Upasani (4169677)

Scatter measures the quality of retinotopy and values decrease in development. by Spencer L. Smith (366143)

WT data of set A398E/V and set M1425V/I pooled for better comparison. by Yousra El Ghaleb (22075892)

Subjects:

<b>Adipose TGR5 deletion promotes hepatic steatosis through decreasing adiponectin secretion in mice</b> by Jiahui Li (646449)

Stx2 and SubAB decrease HGEC viability. by María M. Amaral (439445)

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …”

Nesfatin-1 decreased excitability of GI-neurons in DVC. by Jing Dong (102657)

Acetylation of histone H3 decreases nucleosome stability. by Alexander Gansen (404272)

Calyculin A-induced decrease of tyrosine-monophosphorylated ERK2 at high cell density. by Noriyuki Kawabata (3391739)

Depletion of SNEV decreases the splicing efficiency of nuclear extracts by Johannes Grillari (13055)

“…Lane 1 shows the unspliced adenoviral pre-mRNA. A decrease of the second catalytical step of the reaction was observed in the SNEV depleted extracts when compared to depleted controls, where irrelevant antibodies were used for depletion (lanes 3 and 4) or where untreated NE was used for splicing (lane 2). …”

Decreased number of cilia in partially formed KV lumen. by Jeong-gyun Kim (4330168)

ANG II treatment leads to decreased contractile function. by Renita E. Horton (847891)

“…(E) Representative stress traces generated from x-projections of films (F) ANG II treatment leads to a decrease in contractile stress generation. Control n = 85 tissues, 5 nM n = 15 tissues, 100 nM n = 69 tissues, 3 harvests. …”

Image5_Immunization of Broiler Chickens With a Killed Chitosan Nanoparticle Salmonella Vaccine Decreases Salmonella Enterica Serovar Enteritidis Load.pdf by Keila Acevedo-Villanueva (10531191)

“…Chitosan nanoparticle (CNP) vaccines can be used to deliver Salmonella antigens orally. We investigated the efficacy of a killed Salmonella CNP vaccine on broilers. …”