The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …”

MMR mutants show decreased mating-type silencing. by Qian Liu (135614)

“…MMR deletion strains (<i>pms1Δ</i>, <i>mlh1Δ</i>, and <i>msh2Δ</i>) displayed white with sectors colonies as compared to WT, indicating a loss of gene silencing at the telomere <i>ADE2</i> reporter. …”

MigC interacts with and decreases the activity of MurD. by Jeanette M. Critchlow (21553796)

Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. by Ana Camila Oliveira Souza (8180958)

“…<p><b>A)</b> Analysis of fungal burden by qPCR at day +4 post inoculation. …”

For most sites, observed abundance decreases with size class. by Sarah L. Becker (6631253)

Preserved NSS at 2 and at 24 hours following ischemia and decreased infarct volume in PAR1 KO mice 24 hours following ischemic stroke. by Efrat Shavit-Stein (3186678)

“…(C) Total infarct volume is significantly lower in PAR1 KO mice compared to control (t-test, WT = 6, PAR1 KO = 6). (D) Infarct volume decreases as a function of distance from the ischemic core (slices #5&6). …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Acinetobactin biosynthetic mutants exhibit decreased maximal growth and growth rates, as well as an increased lag time relative to WT <i>A</i>. <i>baumannii</i> ATCC 179789 when gr... by Jessica R. Sheldon (4785675)

Overview of the PEX5 immunofluorescence staining. by Claudia Colasante (101665)

Extended Ensemble Molecular Dynamics Study of Ammonia–Cellulose I Complex Crystal Models: Free-Energy Landscape and Atomistic Pictures of Ammonia Diffusion in the Crystalline Phase... by Toshifumi Yui (1768846)

Subjects:

Extended Ensemble Molecular Dynamics Study of Ammonia–Cellulose I Complex Crystal Models: Free-Energy Landscape and Atomistic Pictures of Ammonia Diffusion in the Crystalline Phase... by Toshifumi Yui (1768846)

Subjects:

Extended Ensemble Molecular Dynamics Study of Ammonia–Cellulose I Complex Crystal Models: Free-Energy Landscape and Atomistic Pictures of Ammonia Diffusion in the Crystalline Phase... by Toshifumi Yui (1768846)

Subjects:

Differences in abundance in liver of <i>Fmo5</i>^<i>-/-</i> and WT mice of products of microbial and host-conjugation reactions. by Ian R. Phillips (5074121)

Predicted upstream regulators and hepatic expression of their genes in <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

Graphical summary of relationships predicted by IPA to be down-regulated in liver of <i>Fmo5</i>^-/- mice compared with WT mice. by Ian R. Phillips (5074121)

CcnA mutation of Loop A decreases the interaction with the 5′ UTR of P2-<i>ctrA</i> mRNA and 5′ UTR of <i>gcrA</i> mRNA. by Wanassa Beroual (5314028)

Sustainable Production of Polyamide 6 Fibers: Direct Melt Spinning and Efficient Reuse of Residual Oligomers during Polymerization by Shengming Zhang (14662719)

Subjects:

Fig 5 - by Zhi Zhang (55283)

SLAMF6 knock down or knock out leads to a decrease in TCR activation. by Matthew A. Dragovich (6843362)