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421
Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
Published 2019“…The formulation of silymarin-HSA nanoplex showed a spherical shape with an average diameter between 50 nm and 150 nm, hydrodynamic radius of 188.3 nm, zeta potential of −26.6 mV, and a drug loading of 97.3%. …”
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422
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis
Published 2019“…Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. …”
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423
DSA-based energy efficient cellular networks: Integration with the smart grid
Published 2016“…We formulate the trade-off situation of the operators as a reward function. The objective is to maximize the reward while decreasing the energy consumption. …”
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424
Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey.
Published 2020“…The association between egg consumption and diabetes is inconclusive. We aimed to examine the association between long-term egg consumption and its trajectory with diabetes in Chinese adults. …”
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425
Nanoclay compatibilization of phase separated polysulfone/polyimide films for oxygen barrier
Published 2017“…Herein, we quantify the effect of a nanoclay, Cloisite 30B on the phase separated blend film morphology compatibilization of PSF/PI and associated changes in its mechanical properties and film surface energy. …”
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426
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427
Dynamic Imaging of Hydrate Specific Area Evolution during Xenon Hydrate Formation
Published 2020“…During hydrate formation and dissociation, full 3D images are acquired at a time resolution of 45 seconds and a spatial resolution of 5.38 ?…”
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428
Integrating Building Information Management (BIM) in Civil Infrastructure Coordination: Application at LUSAIL Plaza
Published 2020“…An exploratory approach on a complex mega-project case study (El-Sadek & McCabe, 2017), where the project team was coached on exploring the BIM model to identify any clash and discuss with the technical team to come up with adequate solutions, which was done by holding twice a week regular meetings. …”
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429
Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter...
Published 2022“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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430
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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431
Therapeutic outcomes and biodistribution of gold nanoparticles in collagen-induced arthritis animal model
Published 2022“…CIA rats were then divided into five groups: CIA model (positive control), AuNPs treated- (sphere shape with size: 5, 25, and 75 nm), and methotrexate (MTX)-treated-rats. …”
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432
Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices
Published 2012“…Main outcome measures: Qatar community pharmacists' smoking cessation practices, their attitudes toward tobacco use, smoking cessation and smoking cessation counseling and their perceived barriers for smoking cessation counseling. Results: Over 5 months, we collected 127 surveys (40 % response rate). …”
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433
Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells
Published 2014“…Cardiovascular diseases (CVDs) are still the number one cause of morbidity and mortality both in Qatar and worldwide. A major risk factor of CVDs is atherosclerosis, the hardening of blood vessels caused by decreased diameter and formation of plaque. …”
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434
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435
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries
Published 2022“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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436
Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
Published 2016“…The pH range for the Clinoleic formulations (7.1–7.5) was slightly higher than that of the Intralipid formulations (6.5–6.9). …”
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437
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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438
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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439
Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate
Published 2020“…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …”
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440
Age-Related Differences of the Athlete`s Heart
Published 2013“…Left ventricle muscle mass (LVMM) is higher in older endurance athletes than in age-matched non-athletes (5) but the difference between athletic and non-athletic subjects decrease continuously or disappears during the ageing. …”
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