Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…The regulatory mechanism of MrgC on UPR^mt was further explored in N2a and 293T cells.</p>Results<p>Mice with bone cancer pain showed improved mRNA and protein levels of UPR^mt-related molecules, increased MMP and ATP, decreased mitochondrial ROS levels in the spinal cord after receiving an intrathecal injection of BAM8-22. …”

Data_Sheet_1_The Abscopal Effects of Cranial Irradiation Induce Testicular Damage in Mice.docx by Ling Guo (9700)

“…<p>To investigate whether the abscopal effects of cranial irradiation (C-irradiation) cause testicular damage in mice, male C57BL/6 mice (9weeks of age) were randomly divided into a sham irradiation group, a shielded group and a C-irradiation group and administered sham/shielded irradiation or C-irradiation at a dose rate of 2.33Gy/min (5Gy/d for 4 d consecutively). …”

Data_Sheet_1_Time-trend analysis of tuberculosis diagnosis in Shenzhen, China between 2011 and 2020.PDF by Chuang-Yue Hong (14648573)

“…Compared with passive case-finding, active case-finding significantly decreased the risk of patient delay by 5.47 (4.85–6.19) times.…”

Data_Sheet_1_Binding of Elementary Bodies by the Opportunistic Fungal Pathogen Candida albicans or Soluble β-Glucan, Laminarin, Inhibits Chlamydia trachomatis Infectivity.pdf by Michael D. Kruppa (339641)

“…However, once bound to C. albicans, EB infectivity decreased at a faster rate than EB in medium alone. …”

Data_Sheet_1_The Abscopal Effects of Cranial Irradiation Induce Testicular Damage in Mice.docx by Ling Guo (9700)

“…<p>To investigate whether the abscopal effects of cranial irradiation (C-irradiation) cause testicular damage in mice, male C57BL/6 mice (9weeks of age) were randomly divided into a sham irradiation group, a shielded group and a C-irradiation group and administered sham/shielded irradiation or C-irradiation at a dose rate of 2.33Gy/min (5Gy/d for 4 d consecutively). …”

table1_CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar.xlsx by Rajeev K. Mehlotra (3211350)

“…<p>Plasmodium vivax is one of the five human malaria parasite species, which has a wide geographical distribution and can cause severe disease and fatal outcomes. …”

Data_Sheet_1_Elongation Factor Thermo Unstable (EF-Tu) Moonlights as an Adhesin on the Surface of Mycoplasma hyopneumoniae by Binding to Fibronectin.CSV by Yanfei Yu (5217422)

“…Recombinant EF-Tu (rEF-Tu) was found to be able to adhere to STEC and anti-rEF-Tu antibody enclosed M. hyopneumoniae decreased adherence to STEC. In addition, surface plasmon resonance (SPR) analysis showed that rEF-Tu could bind to fibronectin with a specific and moderately strong interaction, a dissociation constant (K_D) of 605 nM. …”

Table_1_Olive Leaf Extract Attenuates Inflammatory Activation and DNA Damage in Human Arterial Endothelial Cells.docx by Blaž Burja (6705899)

“…HCAEC were treated with SAA (1,000 nM) and/or OLE (0.5 and 1 mg/ml). The expression of adhesion molecules VCAM-1 and E-selectin, matrix metalloproteinases (MMP2 and MMP9) and microRNA 146a, let-7e, and let-7g (involved in the regulation of inflammation) was determined by qPCR. …”

table2_CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar.xlsx by Rajeev K. Mehlotra (3211350)

“…<p>Plasmodium vivax is one of the five human malaria parasite species, which has a wide geographical distribution and can cause severe disease and fatal outcomes. …”

Table_1_The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020.docx by Valentino Cherubini (9141940)

“…</p>Results<p>Overall, the frequency of DKA increased from 35.7% (95%CI, 33.5-36.9) in 2017-2019 to 39.6% (95%CI, 36.7-42.4) in 2020 (p=0.008), while the frequency of severe DKA increased from 10.4% in 2017-2019 (95%CI, 9.4-11.5) to 14.2% in 2020 (95%CI, 12.3-16.4, p<0.001). …”

Table_1_The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020.docx by Valentino Cherubini (9141940)

“…</p>Results<p>Overall, the frequency of DKA increased from 35.7% (95%CI, 33.5-36.9) in 2017-2019 to 39.6% (95%CI, 36.7-42.4) in 2020 (p=0.008), while the frequency of severe DKA increased from 10.4% in 2017-2019 (95%CI, 9.4-11.5) to 14.2% in 2020 (95%CI, 12.3-16.4, p<0.001). …”

shPHD-2 Suppresses PHD-2 and Upregulates HIF-1α and Downstream Angiogenic Genes In Vitro. by Kevin J. Paik (3180762)

“…<p>Cells for all experiments were cultured under hypoxic conditions of 5% oxygen. (a) Schematics of shPHD-2 and shScr constructs. …”

Table 1_Effects of grassland degradation on soil ecological stoichiometry and soil microbial community on the South of the Greater Khingan Mountains.docx by Yuyu Li (3939137)

“…Grassland degradation significantly decreased soil bacterial and fungal richness. In addition, grassland degradation significantly increased the relative abundance of Firmicutes (from 1.65% to 5.38%) and Myxococcota (from 2.13% to 3.13%). …”

Bicycle Powered Centrifugal Irrigation Pump, Sprint Test Experiment by Abe McKay (4477777)

“…Two pedalers each took 10 trials with the MoneyMaker and 5 trials each with the bicycle pump. We used a Super MoneyMaker, which is an older model than the current MoneyMaker Max treadle pump. …”

Dietary patterns associated with the risk of osteoporosis in postmenopausal women by Tayyem, Reema F.

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Resveratrol inhibits androgen production of human adrenocortical H295R cells by lowering CYP17 and CYP21 expression and activities by Nesa Marti (3851059)

“…Only SIRT3 mRNA expression was found to be altered by resveratrol, but SIRT1, 3 and 5 overexpression did not result in a change in the steroid profile of H295R cells, indicating that resveratrol may not engage sirtuins to modulate steroid production. …”

Data_Sheet_1_The “Obesity Paradox” in Patients With HFpEF With or Without Comorbid Atrial Fibrillation.PDF by Linjuan Guo (11920172)

“…In those with AF, obesity (HR = 0.62, 95% CI: 0.40–0.95) but not overweight (HR = 0.81, 95% CI: 0.54–1.21) was associated with a decreased risk of all-cause death.</p><p>Conclusions: The “obesity paradox” assessed by BMI exists in patients with HFpEF regardless of comorbid AF.…”

Image_4_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.TIFF by Juan Villar-Vesga (4900768)

“…Two distinct forms of Alzheimer disease (AD) are known: a late-onset sporadic form (SAD) and an early-onset familial form (FAD). …”

Table_1_SNORD126 Promotes Hepatitis C Virus Infection by Upregulating Claudin-1 via Activation of PI3K-AKT Signaling Pathway.XLSX by Xijing Qian (9377405)

“…<p>Hepatitis C virus (HCV) infection involves a variety of viral and host factors, some of which promote the infection process. …”

Image_1_MiR-539-3p impairs osteogenesis by suppressing Wnt interaction with LRP-6 co-receptor and subsequent inhibition of Akap-3 signaling pathway.tif by Alok Tripathi (7054172)

“…Target prediction algorithm and experimental confirmation by luciferase 3’ UTR reporter assay identified LRP-6 as a direct target of miR-539-3p. Over expression of miR-539-3p in osteoblasts down regulated Wnt/beta catenin signaling components and deteriorated trabecular microarchitecture leading to decreased bone formation in ovariectomized (Ovx) mice. …”