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Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer
Published 2015“…Two of the five siRNAs tested were found to efficiently inhibit mRNA of both <i>TMPRSS2-ERG</i> variants and to decrease ERG protein expression. …”
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Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study
Published 2016“…We previously demonstrated that early initiation of sustained low-efficiency dialysis (SLED) followed by daily SLED significantly decreases mortality. …”
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324
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A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population
Published 2015“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”
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R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study
Published 2022“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”
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332
R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study
Published 2022“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”
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333
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334
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336
Conditional stabilization of β-catenin decreases frequency of Tbr2-expressing cells.
Published 2010“…This analysis also resulted in a markedly decreased Tbr2+ intermediate progenitor population in cortices (<b>F</b>) when compared to NesCre- control. …”
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337
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338
Activated CD8 T cells in FOXO3−/− mice display decreased apoptosis.
Published 2012“…<p>To address whether the increase in antigen-specific cells observed in FOXO3−/− mice at day 8 was in fact the result of decreased apoptosis, we assessed the relative expression levels of a number of cell survival or cell death markers. …”
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339
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Influence of Acidic pH on Hydrogen and Acetate Production by an Electrosynthetic Microbiome
Published 2014“…Cyclic voltammetry revealed a 250 mV decrease in hydrogen overpotential and a maximum current density of 12.2 mA/cm<sup>2</sup> at −765 mV (0.065 mA/cm<sup>2</sup> sterile control at −800 mV) by the <i>Acetobacterium</i>-dominated community. …”